flunisolide-6023 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

191 genes differentially expressed following the flunisolide-6023 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM22 ADAM metallopeptidase domain 22
ADRA1A adrenoceptor alpha 1A
AHSP alpha hemoglobin stabilizing protein
AKAP1 A kinase (PRKA) anchor protein 1
ALOX5 arachidonate 5-lipoxygenase
AMPH amphiphysin
ATN1 atrophin 1
BMP8B bone morphogenetic protein 8b
BTF3P11 basic transcription factor 3 pseudogene 11
C1ORF116 chromosome 1 open reading frame 116
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CD177 CD177 molecule
CD300A CD300a molecule
CD48 CD48 molecule
CFAP45 cilia and flagella associated protein 45
CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
CNIH3 cornichon family AMPA receptor auxiliary protein 3
COL3A1 collagen, type III, alpha 1
COL5A2 collagen, type V, alpha 2
CTNS cystinosin, lysosomal cystine transporter
DCN decorin
DISC1 disrupted in schizophrenia 1
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
ECE1 endothelin converting enzyme 1
EFNB3 ephrin-B3
EMP1 epithelial membrane protein 1
EZR ezrin
F12 coagulation factor XII (Hageman factor)
FGF4 fibroblast growth factor 4
FGFR1OP FGFR1 oncogene partner
FN1 fibronectin 1
FZD10 frizzled class receptor 10
GABRQ gamma-aminobutyric acid (GABA) A receptor, theta
GALNT8 polypeptide N-acetylgalactosaminyltransferase 8
GARNL3 GTPase activating Rap/RanGAP domain-like 3
GP6 glycoprotein VI (platelet)
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIST1H3I histone cluster 1, H3i
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
HSF1 heat shock transcription factor 1
ICOSLG inducible T-cell co-stimulator ligand
IGFBP3 insulin-like growth factor binding protein 3
KCNE1 potassium channel, voltage gated subfamily E regulatory beta subunit 1
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KEL Kell blood group, metallo-endopeptidase
KLF13 Kruppel-like factor 13
KMT2A lysine (K)-specific methyltransferase 2A
KRT15 keratin 15, type I
LGALS9 lectin, galactoside-binding, soluble, 9
LMTK1 lemur tail kinase 1
LOC441601 septin 7 pseudogene
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MORC1 MORC family CW-type zinc finger 1
NR2E3 nuclear receptor subfamily 2, group E, member 3
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PDGFA platelet-derived growth factor alpha polypeptide
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PURA purine-rich element binding protein A
PVR poliovirus receptor
RAP1GAP RAP1 GTPase activating protein
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RBM12B RNA binding motif protein 12B
REM1 RAS (RAD and GEM)-like GTP-binding 1
SATB2 SATB homeobox 2
SERHL2 serine hydrolase-like 2
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SLC43A3 solute carrier family 43, member 3
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SOX2 SRY (sex determining region Y)-box 2
SP100 SP100 nuclear antigen
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SPRR2B small proline-rich protein 2B
STC1 stanniocalcin 1
STX2 syntaxin 2
TAGLN3 transgelin 3
TBC1D8 TBC1 domain family, member 8 (with GRAM domain)
TBCD tubulin folding cofactor D
TBXA2R thromboxane A2 receptor
TCF3 transcription factor 3
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TNIK TRAF2 and NCK interacting kinase
TNNI3 troponin I type 3 (cardiac)
UBA7 ubiquitin-like modifier activating enzyme 7
UBR4 ubiquitin protein ligase E3 component n-recognin 4
VCAN versican
VWA5A von Willebrand factor A domain containing 5A
ZFP2 ZFP2 zinc finger protein
ZNF280A zinc finger protein 280A
ZNF415 zinc finger protein 415
ZNF446 zinc finger protein 446

decreased expression

Symbol Name
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACTL8 actin-like 8
AHNAK2 AHNAK nucleoprotein 2
ATG10 autophagy related 10
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BAHCC1 BAH domain and coiled-coil containing 1
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
C22ORF46 chromosome 22 open reading frame 46
C2ORF54 chromosome 2 open reading frame 54
C8ORF44 chromosome 8 open reading frame 44
CAPN15 calpain 15
CCDC132 coiled-coil domain containing 132
CCDC69 coiled-coil domain containing 69
CD83 CD83 molecule
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CISH cytokine inducible SH2-containing protein
CLDN15 claudin 15
CLDN17 claudin 17
CRELD1 cysteine-rich with EGF-like domains 1
CRYGC crystallin, gamma C
CTSF cathepsin F
CUZD1 CUB and zona pellucida-like domains 1
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DGAT1 diacylglycerol O-acyltransferase 1
DNM3 dynamin 3
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
EFNA3 ephrin-A3
ERCC6 excision repair cross-complementation group 6
FAM188A family with sequence similarity 188, member A
FMOD fibromodulin
FOXI1 forkhead box I1
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GLCE glucuronic acid epimerase
GPATCH2L G patch domain containing 2-like
GPC3 glypican 3
HIST1H1E histone cluster 1, H1e
HIST1H2AJ histone cluster 1, H2aj
HIST1H4D histone cluster 1, H4d
HPN hepsin
HYI hydroxypyruvate isomerase (putative)
IFI35 interferon-induced protein 35
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IL4R interleukin 4 receptor
IRF6 interferon regulatory factor 6
KLF2 Kruppel-like factor 2
LHX1 LIM homeobox 1
LIME1 Lck interacting transmembrane adaptor 1
LINC00597 long intergenic non-protein coding RNA 597
LONRF3 LON peptidase N-terminal domain and ring finger 3
LRRC20 leucine rich repeat containing 20
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MMP3 matrix metallopeptidase 3
MORN1 MORN repeat containing 1
NDOR1 NADPH dependent diflavin oxidoreductase 1
NNAT neuronatin
NOL10 nucleolar protein 10
NPR3 natriuretic peptide receptor 3
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PDE5A phosphodiesterase 5A, cGMP-specific
POLL polymerase (DNA directed), lambda
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
RAB36 RAB36, member RAS oncogene family
RAD54L2 RAD54-like 2 (S. cerevisiae)
RCAN3 RCAN family member 3
RHBDD3 rhomboid domain containing 3
ROM1 retinal outer segment membrane protein 1
RPGR retinitis pigmentosa GTPase regulator
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SLN sarcolipin
SPAG7 sperm associated antigen 7
STARD13 StAR-related lipid transfer (START) domain containing 13
STIM1 stromal interaction molecule 1
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
THBS3 thrombospondin 3
TMCC2 transmembrane and coiled-coil domain family 2
TMPRSS4 transmembrane protease, serine 4
TOR4A torsin family 4, member A
TRIM5 tripartite motif containing 5
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TUBG2 tubulin, gamma 2
UBTD1 ubiquitin domain containing 1
UNC119 unc-119 homolog (C. elegans)
USB1 U6 snRNA biogenesis 1
USP19 ubiquitin specific peptidase 19
USP20 ubiquitin specific peptidase 20
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
VPS9D1 VPS9 domain containing 1
WDR33 WD repeat domain 33
WDR7 WD repeat domain 7
ZNF37BP zinc finger protein 37B, pseudogene
ZNF428 zinc finger protein 428
ZNF442 zinc finger protein 442
ZNF821 zinc finger protein 821