flunixin-2552 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the flunixin-2552 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ADAM11 ADAM metallopeptidase domain 11
ADCY2 adenylate cyclase 2 (brain)
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
AMPD3 adenosine monophosphate deaminase 3
C11ORF16 chromosome 11 open reading frame 16
C1ORF115 chromosome 1 open reading frame 115
CALD1 caldesmon 1
CARD10 caspase recruitment domain family, member 10
CD68 CD68 molecule
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDK17 cyclin-dependent kinase 17
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CFHR4 complement factor H-related 4
COL14A1 collagen, type XIV, alpha 1
COL8A1 collagen, type VIII, alpha 1
CSHL1 chorionic somatomammotropin hormone-like 1
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DAPK2 death-associated protein kinase 2
DDR1 discoidin domain receptor tyrosine kinase 1
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
DLK2 delta-like 2 homolog (Drosophila)
EDNRA endothelin receptor type A
EFNA5 ephrin-A5
EPHB2 EPH receptor B2
ESR1 estrogen receptor 1
FABP3 fatty acid binding protein 3, muscle and heart
FABP7 fatty acid binding protein 7, brain
FAM106A family with sequence similarity 106, member A
FAM155A family with sequence similarity 155, member A
FBXL2 F-box and leucine-rich repeat protein 2
FGF20 fibroblast growth factor 20
FGF8 fibroblast growth factor 8 (androgen-induced)
FLJ11292
FOXO1 forkhead box O1
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GAP43 growth associated protein 43
GATA3 GATA binding protein 3
GH1 growth hormone 1
GP2 glycoprotein 2 (zymogen granule membrane)
GRIA3 glutamate receptor, ionotropic, AMPA 3
GUCA2A guanylate cyclase activator 2A (guanylin)
GZMK granzyme K (granzyme 3; tryptase II)
HOXA7 homeobox A7
HSPB6 heat shock protein, alpha-crystallin-related, B6
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
IGH immunoglobulin heavy locus
IL12B interleukin 12B
IL1RN interleukin 1 receptor antagonist
IQCA1 IQ motif containing with AAA domain 1
ITPK1 inositol-tetrakisphosphate 1-kinase
KALRN kalirin, RhoGEF kinase
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KIAA0087 KIAA0087
KRT14 keratin 14, type I
KRT81 keratin 81, type II
KSR1 kinase suppressor of ras 1
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LILRA5 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5
LPAR3 lysophosphatidic acid receptor 3
LRP1 low density lipoprotein receptor-related protein 1
LRRC15 leucine rich repeat containing 15
MARCKS myristoylated alanine-rich protein kinase C substrate
MCF2 MCF.2 cell line derived transforming sequence
MUC8 mucin 8
NCR1 natural cytotoxicity triggering receptor 1
NLRP1 NLR family, pyrin domain containing 1
NUP88 nucleoporin 88kDa
NXF2 nuclear RNA export factor 2
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PKP1 plakophilin 1
POU5F1P3 POU class 5 homeobox 1 pseudogene 3
PRB1 proline-rich protein BstNI subfamily 1
PRMT8 protein arginine methyltransferase 8
RAB17 RAB17, member RAS oncogene family
RAB27B RAB27B, member RAS oncogene family
RAD51B RAD51 paralog B
RBBP9 retinoblastoma binding protein 9
RPS4Y1 ribosomal protein S4, Y-linked 1
RS1 retinoschisin 1
SCN2B sodium channel, voltage gated, type II beta subunit
SEZ6L seizure related 6 homolog (mouse)-like
SIX3 SIX homeobox 3
SLC26A1 solute carrier family 26 (anion exchanger), member 1
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SMR3B submaxillary gland androgen regulated protein 3B
SPRR2B small proline-rich protein 2B
TCAF1 TRPM8 channel-associated factor 1
TEF thyrotrophic embryonic factor
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
THPO thrombopoietin
THRA thyroid hormone receptor, alpha
TRD T cell receptor delta locus
TRIM62 tripartite motif containing 62
VIP vasoactive intestinal peptide
WDR1 WD repeat domain 1

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ABHD3 abhydrolase domain containing 3
ADAM23 ADAM metallopeptidase domain 23
AGO3 argonaute RISC catalytic component 3
ARHGAP10 Rho GTPase activating protein 10
ARHGAP12 Rho GTPase activating protein 12
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARMC6 armadillo repeat containing 6
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ASTE1 asteroid homolog 1 (Drosophila)
ATAD3A ATPase family, AAA domain containing 3A
AUH AU RNA binding protein/enoyl-CoA hydratase
C2CD2 C2 calcium-dependent domain containing 2
CA5BP1 carbonic anhydrase VB pseudogene 1
CBX4 chromobox homolog 4
CCDC47 coiled-coil domain containing 47
CCNB1 cyclin B1
CDC37L1 cell division cycle 37-like 1
CENPE centromere protein E, 312kDa
CEP70 centrosomal protein 70kDa
CHMP7 charged multivesicular body protein 7
CLDN15 claudin 15
COLGALT2 collagen beta(1-O)galactosyltransferase 2
CTPS2 CTP synthase 2
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DGAT1 diacylglycerol O-acyltransferase 1
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17
DOLK dolichol kinase
DUSP2 dual specificity phosphatase 2
ECI2 enoyl-CoA delta isomerase 2
FAM127A family with sequence similarity 127, member A
FAM188A family with sequence similarity 188, member A
FBXL6 F-box and leucine-rich repeat protein 6
FBXO3 F-box protein 3
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GCC1 GRIP and coiled-coil domain containing 1
GDE1 glycerophosphodiester phosphodiesterase 1
GPHN gephyrin
GPS2 G protein pathway suppressor 2
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene)
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa
GTF2I general transcription factor IIi
HIST1H1C histone cluster 1, H1c
HRAS Harvey rat sarcoma viral oncogene homolog
IFT46 intraflagellar transport 46
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
KIF23 kinesin family member 23
KIN Kin17 DNA and RNA binding protein
LIMD2 LIM domain containing 2
LIN7A lin-7 homolog A (C. elegans)
LMAN1 lectin, mannose-binding, 1
MAPKAP1 mitogen-activated protein kinase associated protein 1
MECR mitochondrial trans-2-enoyl-CoA reductase
METTL2B methyltransferase like 2B
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MNS1 meiosis-specific nuclear structural 1
MOGS mannosyl-oligosaccharide glucosidase
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MTPAP mitochondrial poly(A) polymerase
MXD3 MAX dimerization protein 3
NCS1 neuronal calcium sensor 1
NDC1 NDC1 transmembrane nucleoporin
NFS1 NFS1 cysteine desulfurase
NIP7 NIP7, nucleolar pre-rRNA processing protein
OTUD3 OTU deubiquitinase 3
OXSM 3-oxoacyl-ACP synthase, mitochondrial
PARG poly (ADP-ribose) glycohydrolase
PRDM13 PR domain containing 13
PROSER1 proline and serine rich 1
PRPF39 pre-mRNA processing factor 39
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
RABEP1 rabaptin, RAB GTPase binding effector protein 1
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RWDD3 RWD domain containing 3
SCRIB scribbled planar cell polarity protein
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
SERINC5 serine incorporator 5
SETD6 SET domain containing 6
SETD8 SET domain containing (lysine methyltransferase) 8
STK25 serine/threonine kinase 25
TBCCD1 TBCC domain containing 1
TEX2 testis expressed 2
TMEM134 transmembrane protein 134
TRMT12 tRNA methyltransferase 12 homolog (S. cerevisiae)
URGCP upregulator of cell proliferation
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
USPL1 ubiquitin specific peptidase like 1
VPS8 vacuolar protein sorting 8 homolog (S. cerevisiae)
WT1-AS WT1 antisense RNA
XAB2 XPA binding protein 2
YIPF5 Yip1 domain family, member 5
ZDHHC14 zinc finger, DHHC-type containing 14
ZDHHC24 zinc finger, DHHC-type containing 24
ZNF141 zinc finger protein 141
ZNF16 zinc finger protein 16
ZNF227 zinc finger protein 227
ZNF32 zinc finger protein 32