flunixin-3411 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the flunixin-3411 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ACTA1 actin, alpha 1, skeletal muscle
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
APOLD1 apolipoprotein L domain containing 1
APOM apolipoprotein M
ATF6 activating transcription factor 6
CCNO cyclin O
CRLF2 cytokine receptor-like factor 2
CSF1 colony stimulating factor 1 (macrophage)
CXCR2 chemokine (C-X-C motif) receptor 2
CYHR1 cysteine/histidine-rich 1
DAPK3 death-associated protein kinase 3
DIEXF digestive organ expansion factor homolog (zebrafish)
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EDA ectodysplasin A
EML1 echinoderm microtubule associated protein like 1
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
ERCC2 excision repair cross-complementation group 2
FAM198B family with sequence similarity 198, member B
FASTKD2 FAST kinase domains 2
FKBP5 FK506 binding protein 5
FMOD fibromodulin
FSCN3 fascin actin-bundling protein 3, testicular
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GM2A GM2 ganglioside activator
GPR143 G protein-coupled receptor 143
GSN gelsolin
HAUS5 HAUS augmin-like complex, subunit 5
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HN1L hematological and neurological expressed 1-like
HR hair growth associated
HS6ST1 heparan sulfate 6-O-sulfotransferase 1
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
IDI2-AS1 IDI2 antisense RNA 1
IFNA17 interferon, alpha 17
IFT140 intraflagellar transport 140
IL11 interleukin 11
IL2RG interleukin 2 receptor, gamma
INPP1 inositol polyphosphate-1-phosphatase
IQCE IQ motif containing E
IRF5 interferon regulatory factor 5
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KCNK10 potassium channel, two pore domain subfamily K, member 10
KRT6B keratin 6B, type II
LAMP3 lysosomal-associated membrane protein 3
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LIME1 Lck interacting transmembrane adaptor 1
LRRC14 leucine rich repeat containing 14
MAP1A microtubule-associated protein 1A
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MARK4 MAP/microtubule affinity-regulating kinase 4
MFAP2 microfibrillar-associated protein 2
MFGE8 milk fat globule-EGF factor 8 protein
MYH14 myosin, heavy chain 14, non-muscle
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NEBL nebulette
NNMT nicotinamide N-methyltransferase
NR6A1 nuclear receptor subfamily 6, group A, member 1
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PHLDB1 pleckstrin homology-like domain, family B, member 1
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLEKHO2 pleckstrin homology domain containing, family O member 2
POPDC3 popeye domain containing 3
PTP4A3 protein tyrosine phosphatase type IVA, member 3
PTPN21 protein tyrosine phosphatase, non-receptor type 21
RAB6A RAB6A, member RAS oncogene family
RAB6B RAB6B, member RAS oncogene family
RAD52 RAD52 homolog (S. cerevisiae)
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic)
RCAN1 regulator of calcineurin 1
REPS1 RALBP1 associated Eps domain containing 1
RGS12 regulator of G-protein signaling 12
RNF170 ring finger protein 170
RPL10L ribosomal protein L10-like
RPL7 ribosomal protein L7
SLC25A40 solute carrier family 25, member 40
SLC35E2 solute carrier family 35, member E2
SMIM14 small integral membrane protein 14
SORBS3 sorbin and SH3 domain containing 3
SRPX sushi-repeat containing protein, X-linked
SVIL supervillin
SYCP2 synaptonemal complex protein 2
TAOK2 TAO kinase 2
TBX19 T-box 19
TDRKH tudor and KH domain containing
TMEM53 transmembrane protein 53
TMPRSS3 transmembrane protease, serine 3
TRIM3 tripartite motif containing 3
TRPC1 transient receptor potential cation channel, subfamily C, member 1
TTC38 tetratricopeptide repeat domain 38
ULBP2 UL16 binding protein 2
WDR1 WD repeat domain 1
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
ZBTB44 zinc finger and BTB domain containing 44
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF10 zinc finger protein 10
ZNF428 zinc finger protein 428

decreased expression

Symbol Name
ADRA2C adrenoceptor alpha 2C
ANKFY1 ankyrin repeat and FYVE domain containing 1
ATAD5 ATPase family, AAA domain containing 5
ATF7IP2 activating transcription factor 7 interacting protein 2
ATG2A autophagy related 2A
AXIN1 axin 1
BTF3P12 basic transcription factor 3 pseudogene 12
C2ORF44 chromosome 2 open reading frame 44
CCNT1 cyclin T1
CDK3 cyclin-dependent kinase 3
CEP131 centrosomal protein 131kDa
CHKB choline kinase beta
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CIC capicua transcriptional repressor
CORO1A coronin, actin binding protein, 1A
CPPED1 calcineurin-like phosphoesterase domain containing 1
CRY1 cryptochrome circadian clock 1
CSTA cystatin A (stefin A)
DET1 de-etiolated homolog 1 (Arabidopsis)
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
ELOVL4 ELOVL fatty acid elongase 4
EPPK1 epiplakin 1
EXOC3 exocyst complex component 3
FAM192A family with sequence similarity 192, member A
FAM222B family with sequence similarity 222, member B
FBXL2 F-box and leucine-rich repeat protein 2
FBXW12 F-box and WD repeat domain containing 12
FHOD1 formin homology 2 domain containing 1
FKBP14 FK506 binding protein 14, 22 kDa
GINS4 GINS complex subunit 4 (Sld5 homolog)
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GPR87 G protein-coupled receptor 87
GPRASP1 G protein-coupled receptor associated sorting protein 1
GRAMD4 GRAM domain containing 4
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
GUSBP3 glucuronidase, beta pseudogene 3
HAUS6 HAUS augmin-like complex, subunit 6
HIRA histone cell cycle regulator
IFT22 intraflagellar transport 22
IL17RA interleukin 17 receptor A
IMPACT impact RWD domain protein
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
KIAA0430 KIAA0430
KIAA0895 KIAA0895
KIF3A kinesin family member 3A
KLHL36 kelch-like family member 36
KREMEN2 kringle containing transmembrane protein 2
KRI1 KRI1 homolog (S. cerevisiae)
LARS leucyl-tRNA synthetase
LMNB2 lamin B2
LOC730101 uncharacterized LOC730101
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LRP5L low density lipoprotein receptor-related protein 5-like
LYPD1 LY6/PLAUR domain containing 1
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MBOAT7 membrane bound O-acyltransferase domain containing 7
MED9 mediator complex subunit 9
MPP5 membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
NBEAL2 neurobeachin-like 2
NDRG1 N-myc downstream regulated 1
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
PBLD phenazine biosynthesis-like protein domain containing
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLD3 phospholipase D family, member 3
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
POR P450 (cytochrome) oxidoreductase
PPP1R13L protein phosphatase 1, regulatory subunit 13 like
PRPH peripherin
PTDSS2 phosphatidylserine synthase 2
RBM38 RNA binding motif protein 38
RFWD3 ring finger and WD repeat domain 3
RNF126P1 ring finger protein 126 pseudogene 1
RPS17P5 ribosomal protein S17 pseudogene 5
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1
SLC4A1AP solute carrier family 4 (anion exchanger), member 1, adaptor protein
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa
SOWAHC sosondowah ankyrin repeat domain family member C
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma)
SUN2 Sad1 and UNC84 domain containing 2
SYT17 synaptotagmin XVII
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae)
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TTC30A tetratricopeptide repeat domain 30A
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WDR76 WD repeat domain 76
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZBTB3 zinc finger and BTB domain containing 3
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF623 zinc finger protein 623
ZNF652 zinc finger protein 652
ZNF778 zinc finger protein 778
ZNF91 zinc finger protein 91