flunixin-3713 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the flunixin-3713 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADCY2 adenylate cyclase 2 (brain)
AGFG1 ArfGAP with FG repeats 1
AGFG2 ArfGAP with FG repeats 2
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ARTN artemin
ATG10 autophagy related 10
B9D1 B9 protein domain 1
BEGAIN brain-enriched guanylate kinase-associated
BMP7 bone morphogenetic protein 7
CALD1 caldesmon 1
CAMK1D calcium/calmodulin-dependent protein kinase ID
CES1 carboxylesterase 1
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
CLCN4 chloride channel, voltage-sensitive 4
CLEC3B C-type lectin domain family 3, member B
COBLL1 cordon-bleu WH2 repeat protein-like 1
COMT catechol-O-methyltransferase
COPZ2 coatomer protein complex, subunit zeta 2
CREB3L1 cAMP responsive element binding protein 3-like 1
DIAPH2 diaphanous-related formin 2
DSCC1 DNA replication and sister chromatid cohesion 1
EGR1 early growth response 1
EVX1 even-skipped homeobox 1
FGF18 fibroblast growth factor 18
FTCD formimidoyltransferase cyclodeaminase
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HEXA hexosaminidase A (alpha polypeptide)
HPX hemopexin
ICA1 islet cell autoantigen 1, 69kDa
KCNIP1 Kv channel interacting protein 1
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
KLK13 kallikrein-related peptidase 13
LAMA2 laminin, alpha 2
LPA lipoprotein, Lp(a)
MED25 mediator complex subunit 25
MLN motilin
MNMIP1 manchette microtubule inner protein 1
MON2 MON2 homolog (S. cerevisiae)
MT1G metallothionein 1G
MUC8 mucin 8
MYO9B myosin IXB
NCOR2 nuclear receptor corepressor 2
NDNF neuron-derived neurotrophic factor
NUP188 nucleoporin 188kDa
OSBP2 oxysterol binding protein 2
PAX2 paired box 2
PBRM1 polybromo 1
PCDHB3 protocadherin beta 3
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PHOX2B paired-like homeobox 2b
POM121L2 POM121 transmembrane nucleoporin-like 2
PTCRA pre T-cell antigen receptor alpha
PTGIS prostaglandin I2 (prostacyclin) synthase
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C)
RASL11B RAS-like, family 11, member B
REC8 REC8 meiotic recombination protein
REM1 RAS (RAD and GEM)-like GTP-binding 1
REPS1 RALBP1 associated Eps domain containing 1
RGS4 regulator of G-protein signaling 4
RPA4 replication protein A4, 30kDa
RPH3A rabphilin 3A
RUNX1 runt-related transcription factor 1
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SDS serine dehydratase
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SELPLG selectin P ligand
SENP5 SUMO1/sentrin specific peptidase 5
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SIGLEC8 sialic acid binding Ig-like lectin 8
SIRPA signal-regulatory protein alpha
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SORBS2 sorbin and SH3 domain containing 2
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SPRR3 small proline-rich protein 3
SRCAP Snf2-related CREBBP activator protein
SSTR5 somatostatin receptor 5
SV2B synaptic vesicle glycoprotein 2B
SYCE1L synaptonemal complex central element protein 1-like
SYT2 synaptotagmin II
T T, brachyury homolog (mouse)
TBX1 T-box 1
TMEM176A transmembrane protein 176A
TNN tenascin N
TRAF4 TNF receptor-associated factor 4
TRIM25 tripartite motif containing 25
UBR4 ubiquitin protein ligase E3 component n-recognin 4
VAC14 Vac14 homolog (S. cerevisiae)
WDR78 WD repeat domain 78
XDH xanthine dehydrogenase
ZMYND8 zinc finger, MYND-type containing 8
ZNF155 zinc finger protein 155
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADAP2 ArfGAP with dual PH domains 2
ADCY6 adenylate cyclase 6
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
ALPP alkaline phosphatase, placental
ANKH ANKH inorganic pyrophosphate transport regulator
ARSB arylsulfatase B
AURKC aurora kinase C
BDKRB1 bradykinin receptor B1
C3 complement component 3
C5ORF42 chromosome 5 open reading frame 42
CCDC7 coiled-coil domain containing 7
CCDC71 coiled-coil domain containing 71
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CLCA1 chloride channel accessory 1
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CNPY4 canopy FGF signaling regulator 4
CTC1 CTS telomere maintenance complex component 1
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1
DENND2D DENN/MADD domain containing 2D
DGKE diacylglycerol kinase, epsilon 64kDa
DMBT1 deleted in malignant brain tumors 1
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EDC3 enhancer of mRNA decapping 3
EPN3 epsin 3
ERN2 endoplasmic reticulum to nucleus signaling 2
EXD3 exonuclease 3'-5' domain containing 3
EXO5 exonuclease 5
FBXL15 F-box and leucine-rich repeat protein 15
FBXL7 F-box and leucine-rich repeat protein 7
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
GAREM GRB2 associated, regulator of MAPK1
GSTCD glutathione S-transferase, C-terminal domain containing
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIST1H2AJ histone cluster 1, H2aj
HOXA7 homeobox A7
IL15RA interleukin 15 receptor, alpha
KDM4D lysine (K)-specific demethylase 4D
KIAA1549L KIAA1549-like
KRT86 keratin 86, type II
LINC00341 long intergenic non-protein coding RNA 341
LYPD3 LY6/PLAUR domain containing 3
MARK1 MAP/microtubule affinity-regulating kinase 1
MBNL3 muscleblind-like splicing regulator 3
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MCMBP minichromosome maintenance complex binding protein
MED31 mediator complex subunit 31
MLYCD malonyl-CoA decarboxylase
MMP9 matrix metallopeptidase 9
MRPL44 mitochondrial ribosomal protein L44
MX1 MX dynamin-like GTPase 1
NPY1R neuropeptide Y receptor Y1
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
PACS1 phosphofurin acidic cluster sorting protein 1
PAIP2B poly(A) binding protein interacting protein 2B
PER3 period circadian clock 3
PODNL1 podocan-like 1
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRR15L proline rich 15-like
RGS19 regulator of G-protein signaling 19
S100A3 S100 calcium binding protein A3
SCAI suppressor of cancer cell invasion
SCEL sciellin
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SETD1A SET domain containing 1A
SH3BGR SH3 domain binding glutamate-rich protein
SLC12A8 solute carrier family 12, member 8
SLC16A6 solute carrier family 16, member 6
SLC22A14 solute carrier family 22, member 14
SLC4A1AP solute carrier family 4 (anion exchanger), member 1, adaptor protein
SLN sarcolipin
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
STAG3L4 stromal antigen 3-like 4 (pseudogene)
SUGCT succinyl-CoA:glutarate-CoA transferase
SYT17 synaptotagmin XVII
TAGLN transgelin
TICAM1 toll-like receptor adaptor molecule 1
TMEM180 transmembrane protein 180
TMEM74B transmembrane protein 74B
TRAC T cell receptor alpha constant
TUBB2B tubulin, beta 2B class IIb
UNC93B1 unc-93 homolog B1 (C. elegans)
USP6NL USP6 N-terminal like
VGF VGF nerve growth factor inducible
VLDLR very low density lipoprotein receptor
WDR4 WD repeat domain 4
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZNF205 zinc finger protein 205
ZNF214 zinc finger protein 214
ZNF222 zinc finger protein 222
ZNF442 zinc finger protein 442
ZNF749 zinc finger protein 749
ZNF76 zinc finger protein 76
ZNF778 zinc finger protein 778
ZNF862 zinc finger protein 862