fluocinonide-3414 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the fluocinonide-3414 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A2M alpha-2-macroglobulin
ADAP1 ArfGAP with dual PH domains 1
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
APLP2 amyloid beta (A4) precursor-like protein 2
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
ARID5A AT rich interactive domain 5A (MRF1-like)
ARL4C ADP-ribosylation factor-like 4C
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BBS9 Bardet-Biedl syndrome 9
BLZF1 basic leucine zipper nuclear factor 1
BTBD7 BTB (POZ) domain containing 7
C11ORF30 chromosome 11 open reading frame 30
C14ORF79 chromosome 14 open reading frame 79
C22ORF46 chromosome 22 open reading frame 46
CACFD1 calcium channel flower domain containing 1
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CASP1 caspase 1, apoptosis-related cysteine peptidase
CCDC132 coiled-coil domain containing 132
CCDC134 coiled-coil domain containing 134
CCDC85C coiled-coil domain containing 85C
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CSF1 colony stimulating factor 1 (macrophage)
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
DIO2 deiodinase, iodothyronine, type II
DLC1 DLC1 Rho GTPase activating protein
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DOC2A double C2-like domains, alpha
DUSP2 dual specificity phosphatase 2
EML1 echinoderm microtubule associated protein like 1
EVA1B eva-1 homolog B (C. elegans)
FAM120C family with sequence similarity 120C
FKBP8 FK506 binding protein 8, 38kDa
FOXN2 forkhead box N2
GNRHR gonadotropin-releasing hormone receptor
GREB1 growth regulation by estrogen in breast cancer 1
GSTA4 glutathione S-transferase alpha 4
HLA-C major histocompatibility complex, class I, C
HR hair growth associated
HSPG2 heparan sulfate proteoglycan 2
ICAM1 intercellular adhesion molecule 1
IRS2 insulin receptor substrate 2
ITPK1 inositol-tetrakisphosphate 1-kinase
JAKMIP2 janus kinase and microtubule interacting protein 2
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3
KIAA1462 KIAA1462
LAMC2 laminin, gamma 2
LMAN1 lectin, mannose-binding, 1
LPCAT4 lysophosphatidylcholine acyltransferase 4
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MINK1 misshapen-like kinase 1
MYOF myoferlin
NKX3-2 NK3 homeobox 2
NLRX1 NLR family member X1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OTUD7B OTU deubiquitinase 7B
PACS1 phosphofurin acidic cluster sorting protein 1
PARD3 par-3 family cell polarity regulator
PDE9A phosphodiesterase 9A
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
POLL polymerase (DNA directed), lambda
POLR2J4 polymerase (RNA) II (DNA directed) polypeptide J4, pseudogene
POPDC3 popeye domain containing 3
POU2F2 POU class 2 homeobox 2
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PSG6 pregnancy specific beta-1-glycoprotein 6
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
RAB6A RAB6A, member RAS oncogene family
RASAL2 RAS protein activator like 2
REM1 RAS (RAD and GEM)-like GTP-binding 1
RGS14 regulator of G-protein signaling 14
RNF43 ring finger protein 43
RUNDC3B RUN domain containing 3B
RYR2 ryanodine receptor 2 (cardiac)
SCAMP1 secretory carrier membrane protein 1
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
STK11 serine/threonine kinase 11
STK17A serine/threonine kinase 17a
SUGP2 SURP and G patch domain containing 2
TADA2A transcriptional adaptor 2A
TAZ tafazzin
TBX19 T-box 19
TGM2 transglutaminase 2
TLE4 transducin-like enhancer of split 4
TOP3B topoisomerase (DNA) III beta
TPK1 thiamin pyrophosphokinase 1
TREX1 three prime repair exonuclease 1
UNC119 unc-119 homolog (C. elegans)
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF419 zinc finger protein 419
ZNF552 zinc finger protein 552
ZNF771 zinc finger protein 771
ZNF816 zinc finger protein 816
ZSCAN18 zinc finger and SCAN domain containing 18

decreased expression

Symbol Name
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ANAPC2 anaphase promoting complex subunit 2
ANXA1 annexin A1
ARMC6 armadillo repeat containing 6
ARRB1 arrestin, beta 1
ATAD2B ATPase family, AAA domain containing 2B
ATAD5 ATPase family, AAA domain containing 5
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
BCORL1 BCL6 corepressor-like 1
BTBD2 BTB (POZ) domain containing 2
CALCOCO1 calcium binding and coiled-coil domain 1
CASP3 caspase 3, apoptosis-related cysteine peptidase
CDK3 cyclin-dependent kinase 3
CHMP7 charged multivesicular body protein 7
CUEDC1 CUE domain containing 1
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DSN1 DSN1, MIS12 kinetochore complex component
DVL1 dishevelled segment polarity protein 1
EAF2 ELL associated factor 2
EPN3 epsin 3
EPPK1 epiplakin 1
ERCC6L excision repair cross-complementation group 6-like
FAM192A family with sequence similarity 192, member A
GBP2 guanylate binding protein 2, interferon-inducible
GDAP1 ganglioside induced differentiation associated protein 1
GINS4 GINS complex subunit 4 (Sld5 homolog)
GLCE glucuronic acid epimerase
GLS2 glutaminase 2 (liver, mitochondrial)
GMIP GEM interacting protein
GNA12 guanine nucleotide binding protein (G protein) alpha 12
GTPBP6 GTP binding protein 6 (putative)
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase
HIRA histone cell cycle regulator
HIST1H2BC histone cluster 1, H2bc
IGSF1 immunoglobulin superfamily, member 1
JUNB jun B proto-oncogene
KIAA0355 KIAA0355
KPTN kaptin (actin binding protein)
KREMEN2 kringle containing transmembrane protein 2
KRT13 keratin 13, type I
LOC730101 uncharacterized LOC730101
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
MAGEH1 melanoma antigen family H1
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MGC12488
MON1B MON1 secretory trafficking family member B
MRPL52 mitochondrial ribosomal protein L52
MYO1D myosin ID
NDRG4 NDRG family member 4
NFE2L3 nuclear factor, erythroid 2-like 3
NR1H2 nuclear receptor subfamily 1, group H, member 2
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PCDHB3 protocadherin beta 3
PELP1 proline, glutamate and leucine rich protein 1
PIGA phosphatidylinositol glycan anchor biosynthesis, class A
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PNKP polynucleotide kinase 3'-phosphatase
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
PSKH1 protein serine kinase H1
PTDSS2 phosphatidylserine synthase 2
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RBL1 retinoblastoma-like 1
RNF123 ring finger protein 123
RNF31 ring finger protein 31
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SMAD7 SMAD family member 7
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SRD5A3 steroid 5 alpha-reductase 3
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STARD13 StAR-related lipid transfer (START) domain containing 13
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
TAGLN transgelin
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM104 transmembrane protein 104
TPST2 tyrosylprotein sulfotransferase 2
TRAIP TRAF interacting protein
TRAPPC13 trafficking protein particle complex 13
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TTC17 tetratricopeptide repeat domain 17
TTC30A tetratricopeptide repeat domain 30A
VEGFC vascular endothelial growth factor C
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
WDR19 WD repeat domain 19
WDR76 WD repeat domain 76
ZBTB3 zinc finger and BTB domain containing 3
ZCCHC2 zinc finger, CCHC domain containing 2
ZNF134 zinc finger protein 134
ZNF189 zinc finger protein 189
ZNF480 zinc finger protein 480
ZNF652 zinc finger protein 652
ZNF675 zinc finger protein 675
ZSCAN26 zinc finger and SCAN domain containing 26