fluocinonide-3757 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the fluocinonide-3757 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACE2 angiotensin I converting enzyme 2
ACTN2 actinin, alpha 2
ADAM22 ADAM metallopeptidase domain 22
ADCK2 aarF domain containing kinase 2
ANGPTL4 angiopoietin-like 4
ARID5A AT rich interactive domain 5A (MRF1-like)
ARL4D ADP-ribosylation factor-like 4D
ARPIN actin-related protein 2/3 complex inhibitor
ATN1 atrophin 1
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2
C1ORF95 chromosome 1 open reading frame 95
C5ORF45 chromosome 5 open reading frame 45
CABP1 calcium binding protein 1
CACNA1F calcium channel, voltage-dependent, L type, alpha 1F subunit
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CASP2 caspase 2, apoptosis-related cysteine peptidase
CCL22 chemokine (C-C motif) ligand 22
CHI3L2 chitinase 3-like 2
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal)
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
COLEC10 collectin sub-family member 10 (C-type lectin)
CT62 cancer/testis antigen 62
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP3A7 cytochrome P450, family 3, subfamily A, polypeptide 7
DNAH17 dynein, axonemal, heavy chain 17
DUSP1 dual specificity phosphatase 1
EMX1 empty spiracles homeobox 1
ERC1 ELKS/RAB6-interacting/CAST family member 1
FAAH fatty acid amide hydrolase
FAM49A family with sequence similarity 49, member A
FBXO31 F-box protein 31
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FLJ10038 uncharacterized protein FLJ10038
FMNL1 formin-like 1
FRMD4B FERM domain containing 4B
GADD45GIP1 growth arrest and DNA-damage-inducible, gamma interacting protein 1
GGT1 gamma-glutamyltransferase 1
GHRHR growth hormone releasing hormone receptor
GYG2 glycogenin 2
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HDAC11 histone deacetylase 11
HPX hemopexin
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
IGF1 insulin-like growth factor 1 (somatomedin C)
IRF4 interferon regulatory factor 4
JADE2 jade family PHD finger 2
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
KIF13A kinesin family member 13A
KLF13 Kruppel-like factor 13
KLK1 kallikrein 1
KLK10 kallikrein-related peptidase 10
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
LAMA2 laminin, alpha 2
LIMCH1 LIM and calponin homology domains 1
LPA lipoprotein, Lp(a)
MAGEA5 melanoma antigen family A5
MATK megakaryocyte-associated tyrosine kinase
MEFV Mediterranean fever
MIER2 mesoderm induction early response 1, family member 2
MMP17 matrix metallopeptidase 17 (membrane-inserted)
MMP7 matrix metallopeptidase 7
MSX2 msh homeobox 2
MUC3B mucin 3B, cell surface associated
MYO9B myosin IXB
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NNMT nicotinamide N-methyltransferase
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OXCT2 3-oxoacid CoA transferase 2
PAWR PRKC, apoptosis, WT1, regulator
PDLIM5 PDZ and LIM domain 5
PER1 period circadian clock 1
PKD1 polycystic kidney disease 1 (autosomal dominant)
PLP1 proteolipid protein 1
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
RASA3 RAS p21 protein activator 3
S100A5 S100 calcium binding protein A5
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLCO1C1 solute carrier organic anion transporter family, member 1C1
TACC1 transforming, acidic coiled-coil containing protein 1
TBC1D2 TBC1 domain family, member 2
TBC1D22B TBC1 domain family, member 22B
TBC1D29 TBC1 domain family, member 29
TCF15 transcription factor 15 (basic helix-loop-helix)
TCF7 transcription factor 7 (T-cell specific, HMG-box)
TESC tescalcin
TGM4 transglutaminase 4
TM4SF4 transmembrane 4 L six family member 4
TMPRSS5 transmembrane protease, serine 5
TNS4 tensin 4
TPSAB1 tryptase alpha/beta 1
TSKS testis-specific serine kinase substrate
TTC22 tetratricopeptide repeat domain 22
TUBB1 tubulin, beta 1 class VI
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked
ZNF506 zinc finger protein 506

decreased expression

Symbol Name
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ANKRD10 ankyrin repeat domain 10
AP4M1 adaptor-related protein complex 4, mu 1 subunit
ARMC4 armadillo repeat containing 4
ATG10 autophagy related 10
BCL2A1 BCL2-related protein A1
C19ORF40 chromosome 19 open reading frame 40
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CAPN5 calpain 5
CCDC186 coiled-coil domain containing 186
CCP110 centriolar coiled coil protein 110kDa
CD70 CD70 molecule
CD79B CD79b molecule, immunoglobulin-associated beta
CD82 CD82 molecule
CHM choroideremia (Rab escort protein 1)
CLEC2B C-type lectin domain family 2, member B
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CRELD1 cysteine-rich with EGF-like domains 1
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DNAH7 dynein, axonemal, heavy chain 7
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1
DOCK1 dedicator of cytokinesis 1
DPF3 D4, zinc and double PHD fingers, family 3
DTX2 deltex 2, E3 ubiquitin ligase
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EGLN3 egl-9 family hypoxia-inducible factor 3
EXOC5 exocyst complex component 5
FKRP fukutin related protein
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GMPR guanosine monophosphate reductase
H1F0 H1 histone family, member 0
HDAC9 histone deacetylase 9
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIRA histone cell cycle regulator
HIST1H2AB histone cluster 1, H2ab
HSPA2 heat shock 70kDa protein 2
IL11RA interleukin 11 receptor, alpha
KDM8 lysine (K)-specific demethylase 8
LOC100127972 uncharacterized LOC100127972
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LRRC37A4P leucine rich repeat containing 37, member A4, pseudogene
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LYPD1 LY6/PLAUR domain containing 1
MAP3K7CL MAP3K7 C-terminal like
MCOLN3 mucolipin 3
MMP3 matrix metallopeptidase 3
MON1B MON1 secretory trafficking family member B
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MXD3 MAX dimerization protein 3
NPM3 nucleophosmin/nucleoplasmin 3
NTSR1 neurotensin receptor 1 (high affinity)
OLFML2A olfactomedin-like 2A
OSMR oncostatin M receptor
PAQR5 progestin and adipoQ receptor family member V
PEX26 peroxisomal biogenesis factor 26
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PPP6R3 protein phosphatase 6, regulatory subunit 3
PTPRS protein tyrosine phosphatase, receptor type, S
PXMP4 peroxisomal membrane protein 4, 24kDa
R3HCC1L R3H domain and coiled-coil containing 1-like
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RARS arginyl-tRNA synthetase
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RPL10L ribosomal protein L10-like
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
RUNX1-IT1 RUNX1 intronic transcript 1
SAMD9 sterile alpha motif domain containing 9
SCG2 secretogranin II
SCNN1B sodium channel, non voltage gated 1 beta subunit
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
SETD1A SET domain containing 1A
SGK2 serum/glucocorticoid regulated kinase 2
SIRAL2 SIR2 antiphage like 2
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SPIDR scaffolding protein involved in DNA repair
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
SRD5A3 steroid 5 alpha-reductase 3
STK16 serine/threonine kinase 16
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TIGD6 tigger transposable element derived 6
TM7SF2 transmembrane 7 superfamily member 2
TMEM156 transmembrane protein 156
TMEM57 transmembrane protein 57
TRAPPC13 trafficking protein particle complex 13
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TSPAN2 tetraspanin 2
VEZT vezatin, adherens junctions transmembrane protein
WFDC2 WAP four-disulfide core domain 2
WT1-AS WT1 antisense RNA
YEATS4 YEATS domain containing 4
ZBTB6 zinc finger and BTB domain containing 6
ZNF222 zinc finger protein 222
ZNF286A zinc finger protein 286A
ZNF480 zinc finger protein 480