fluocinonide-3933 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the fluocinonide-3933 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AGO4 argonaute RISC catalytic component 4
AHNAK AHNAK nucleoprotein
ANG angiogenin, ribonuclease, RNase A family, 5
APLP1 amyloid beta (A4) precursor-like protein 1
ASCL1 achaete-scute family bHLH transcription factor 1
ATP11A ATPase, class VI, type 11A
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BCL2L10 BCL2-like 10 (apoptosis facilitator)
C6 complement component 6
CA7 carbonic anhydrase VII
CA9 carbonic anhydrase IX
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CCDC70 coiled-coil domain containing 70
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CD6 CD6 molecule
CD70 CD70 molecule
CLIP2 CAP-GLY domain containing linker protein 2
CLSTN3 calsyntenin 3
COL6A1 collagen, type VI, alpha 1
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein)
DCN decorin
EFCAB11 EF-hand calcium binding domain 11
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
EPYC epiphycan
EXPH5 exophilin 5
FBLN1 fibulin 1
FGA fibrinogen alpha chain
FGF2 fibroblast growth factor 2 (basic)
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXO4 forkhead box O4
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
GHRH growth hormone releasing hormone
GP2 glycoprotein 2 (zymogen granule membrane)
GPR15 G protein-coupled receptor 15
GYPB glycophorin B (MNS blood group)
HIST1H3A histone cluster 1, H3a
HIST1H3I histone cluster 1, H3i
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HOXD11 homeobox D11
HTN1 histatin 1
HYAL3 hyaluronoglucosaminidase 3
IGFALS insulin-like growth factor binding protein, acid labile subunit
IGLJ3 immunoglobulin lambda joining 3
ITGA7 integrin, alpha 7
KHK ketohexokinase (fructokinase)
KIAA1549L KIAA1549-like
KRT15 keratin 15, type I
KRT8 keratin 8, type II
L1TD1 LINE-1 type transposase domain containing 1
LIME1 Lck interacting transmembrane adaptor 1
LMX1B LIM homeobox transcription factor 1, beta
LRRC37BP1 leucine rich repeat containing 37B pseudogene 1
MAGEA3 melanoma antigen family A3
MEGF6 multiple EGF-like-domains 6
MKRN3 makorin ring finger protein 3
NEB nebulin
NOX1 NADPH oxidase 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NR6A1 nuclear receptor subfamily 6, group A, member 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PDLIM3 PDZ and LIM domain 3
PER1 period circadian clock 1
PICK1 protein interacting with PRKCA 1
PLAT plasminogen activator, tissue
PLCE1 phospholipase C, epsilon 1
PRDM14 PR domain containing 14
PRELP proline/arginine-rich end leucine-rich repeat protein
PVT1 Pvt1 oncogene (non-protein coding)
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RBMS2 RNA binding motif, single stranded interacting protein 2
RERE arginine-glutamic acid dipeptide (RE) repeats
RFX2 regulatory factor X, 2 (influences HLA class II expression)
RUNX1 runt-related transcription factor 1
SCAND2P SCAN domain containing 2 pseudogene
SCG2 secretogranin II
SCN10A sodium channel, voltage gated, type X alpha subunit
SCUBE3 signal peptide, CUB domain, EGF-like 3
SERHL2 serine hydrolase-like 2
SIGLEC8 sialic acid binding Ig-like lectin 8
SIT1 signaling threshold regulating transmembrane adaptor 1
SIX3 SIX homeobox 3
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC48A1 solute carrier family 48 (heme transporter), member 1
SMG6 SMG6 nonsense mediated mRNA decay factor
SORBS2 sorbin and SH3 domain containing 2
SPEF1 sperm flagellar 1
SPON2 spondin 2, extracellular matrix protein
SPTBN5 spectrin, beta, non-erythrocytic 5
SSX1 synovial sarcoma, X breakpoint 1
SSX3 synovial sarcoma, X breakpoint 3
TDRD12 tudor domain containing 12
TNXB tenascin XB
TREM2 triggering receptor expressed on myeloid cells 2
UBA6 ubiquitin-like modifier activating enzyme 6
UBE2I ubiquitin-conjugating enzyme E2I
WNT16 wingless-type MMTV integration site family, member 16
WNT2B wingless-type MMTV integration site family, member 2B
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
ACBD4 acyl-CoA binding domain containing 4
ACPP acid phosphatase, prostate
ADAP2 ArfGAP with dual PH domains 2
ADCY7 adenylate cyclase 7
ADM adrenomedullin
AHSP alpha hemoglobin stabilizing protein
APOM apolipoprotein M
ARC activity-regulated cytoskeleton-associated protein
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BCO1 beta-carotene oxygenase 1
BHLHE41 basic helix-loop-helix family, member e41
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
C11ORF30 chromosome 11 open reading frame 30
C17ORF53 chromosome 17 open reading frame 53
C17ORF80 chromosome 17 open reading frame 80
C1ORF105 chromosome 1 open reading frame 105
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CAMK1 calcium/calmodulin-dependent protein kinase I
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC121 coiled-coil domain containing 121
CD82 CD82 molecule
CDK18 cyclin-dependent kinase 18
CDKL3 cyclin-dependent kinase-like 3
CLCN6 chloride channel, voltage-sensitive 6
CLEC4E C-type lectin domain family 4, member E
CNR2 cannabinoid receptor 2 (macrophage)
COBL cordon-bleu WH2 repeat protein
CORT cortistatin
CPA4 carboxypeptidase A4
CPEB3 cytoplasmic polyadenylation element binding protein 3
DGKE diacylglycerol kinase, epsilon 64kDa
DNAL4 dynein, axonemal, light chain 4
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DRD1 dopamine receptor D1
DTX2 deltex 2, E3 ubiquitin ligase
EXOC6B exocyst complex component 6B
F2R coagulation factor II (thrombin) receptor
FAM110B family with sequence similarity 110, member B
FLCN folliculin
FLJ11710 uncharacterized protein FLJ11710
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GEM GTP binding protein overexpressed in skeletal muscle
GPR143 G protein-coupled receptor 143
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GUSBP3 glucuronidase, beta pseudogene 3
HDAC11 histone deacetylase 11
HIRA histone cell cycle regulator
HLA-DMA major histocompatibility complex, class II, DM alpha
HMOX1 heme oxygenase 1
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HOXC13 homeobox C13
HSF2BP heat shock transcription factor 2 binding protein
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IGSF1 immunoglobulin superfamily, member 1
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IPO8 importin 8
IQSEC2 IQ motif and Sec7 domain 2
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KLF2 Kruppel-like factor 2
KLRG1 killer cell lectin-like receptor subfamily G, member 1
LMTK2 lemur tyrosine kinase 2
LZTS3 leucine zipper, putative tumor suppressor family member 3
MANBA mannosidase, beta A, lysosomal
MCC mutated in colorectal cancers
MDM4 MDM4, p53 regulator
MTCP1 mature T-cell proliferation 1
NOTCH4 notch 4
OASL 2'-5'-oligoadenylate synthetase-like
OSGIN1 oxidative stress induced growth inhibitor 1
PDE12 phosphodiesterase 12
PHEX phosphate regulating endopeptidase homolog, X-linked
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLA2G3 phospholipase A2, group III
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLCD1 phospholipase C, delta 1
PLEKHO2 pleckstrin homology domain containing, family O member 2
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAB40C RAB40C, member RAS oncogene family
RASAL1 RAS protein activator like 1 (GAP1 like)
RFXAP regulatory factor X-associated protein
RPA4 replication protein A4, 30kDa
RPH3A rabphilin 3A
SLC16A4 solute carrier family 16, member 4
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SLMO1 slowmo homolog 1 (Drosophila)
SSTR4 somatostatin receptor 4
TMEM254 transmembrane protein 254
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
UNC119 unc-119 homolog (C. elegans)
USB1 U6 snRNA biogenesis 1
ZBTB44 zinc finger and BTB domain containing 44
ZBTB6 zinc finger and BTB domain containing 6
ZNF532 zinc finger protein 532
ZNF552 zinc finger protein 552
ZNF747 zinc finger protein 747