| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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194 genes differentially expressed following the fluoxetine-2453 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTN2 | actinin, alpha 2 |
| ADCY9 | adenylate cyclase 9 |
| AIF1 | allograft inflammatory factor 1 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 |
| AREG | amphiregulin |
| ATF7 | activating transcription factor 7 |
| AURKA | aurora kinase A |
| BACH1 | BTB and CNC homology 1, basic leucine zipper transcription factor 1 |
| BCAS3 | breast carcinoma amplified sequence 3 |
| BCL6 | B-cell CLL/lymphoma 6 |
| BCR | breakpoint cluster region |
| BRF1 | BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit |
| C11ORF16 | chromosome 11 open reading frame 16 |
| C16ORF45 | chromosome 16 open reading frame 45 |
| C1ORF68 | chromosome 1 open reading frame 68 |
| CACNB3 | calcium channel, voltage-dependent, beta 3 subunit |
| CACNG4 | calcium channel, voltage-dependent, gamma subunit 4 |
| CBR3 | carbonyl reductase 3 |
| CCDC85C | coiled-coil domain containing 85C |
| CCSER2 | coiled-coil serine-rich protein 2 |
| CHN2 | chimerin 2 |
| CLOCK | clock circadian regulator |
| COL9A3 | collagen, type IX, alpha 3 |
| CROT | carnitine O-octanoyltransferase |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| DLC1 | DLC1 Rho GTPase activating protein |
| DSC3 | desmocollin 3 |
| DTNB | dystrobrevin, beta |
| EDRF1 | erythroid differentiation regulatory factor 1 |
| EIF1 | eukaryotic translation initiation factor 1 |
| EML2 | echinoderm microtubule associated protein like 2 |
| EPOR | erythropoietin receptor |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 |
| FCAR | Fc fragment of IgA receptor |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GJC2 | gap junction protein, gamma 2, 47kDa |
| GMPR | guanosine monophosphate reductase |
| GPR161 | G protein-coupled receptor 161 |
| GSDMB | gasdermin B |
| GSK3A | glycogen synthase kinase 3 alpha |
| GTSE1 | G-2 and S-phase expressed 1 |
| HOXD11 | homeobox D11 |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| INO80B | INO80 complex subunit B |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| JUND | jun D proto-oncogene |
| KIF5A | kinesin family member 5A |
| LENEP | lens epithelial protein |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LTBP2 | latent transforming growth factor beta binding protein 2 |
| MAP3K6 | mitogen-activated protein kinase kinase kinase 6 |
| MAP4 | microtubule-associated protein 4 |
| MAPK14 | mitogen-activated protein kinase 14 |
| METTL7A | methyltransferase like 7A |
| MFSD7 | major facilitator superfamily domain containing 7 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) |
| NDRG2 | NDRG family member 2 |
| NPC1 | Niemann-Pick disease, type C1 |
| OLFM1 | olfactomedin 1 |
| OR10J1 | olfactory receptor, family 10, subfamily J, member 1 |
| OTUB1 | OTU deubiquitinase, ubiquitin aldehyde binding 1 |
| PCDHB1 | protocadherin beta 1 |
| PDE4C | phosphodiesterase 4C, cAMP-specific |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 |
| PHACTR4 | phosphatase and actin regulator 4 |
| PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase, type II, beta |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLCD1 | phospholipase C, delta 1 |
| PLK3 | polo-like kinase 3 |
| PRY | PTPN13-like, Y-linked |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 |
| RPL10L | ribosomal protein L10-like |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| RXRB | retinoid X receptor, beta |
| SEC24A | SEC24 family member A |
| SGCD | sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) |
| SIGLEC8 | sialic acid binding Ig-like lectin 8 |
| SIGLEC9 | sialic acid binding Ig-like lectin 9 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 |
| SLCO2B1 | solute carrier organic anion transporter family, member 2B1 |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SVEP1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 |
| SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) |
| TAT | tyrosine aminotransferase |
| TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| TNFSF14 | tumor necrosis factor (ligand) superfamily, member 14 |
| TPM1 | tropomyosin 1 (alpha) |
| TRIM25 | tripartite motif containing 25 |
| WDR55 | WD repeat domain 55 |
| ZC3H13 | zinc finger CCCH-type containing 13 |
| ZNF665 | zinc finger protein 665 |
| ZNF93 | zinc finger protein 93 |
| Symbol | Name |
|---|---|
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 |
| ADTRP | androgen-dependent TFPI-regulating protein |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 |
| ATHL1 | ATH1, acid trehalase-like 1 (yeast) |
| ATP7B | ATPase, Cu++ transporting, beta polypeptide |
| BAK1 | BCL2-antagonist/killer 1 |
| BCAR3 | breast cancer anti-estrogen resistance 3 |
| BEST1 | bestrophin 1 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C9ORF91 | chromosome 9 open reading frame 91 |
| CCDC71 | coiled-coil domain containing 71 |
| CD79A | CD79a molecule, immunoglobulin-associated alpha |
| CENPB | centromere protein B, 80kDa |
| CENPT | centromere protein T |
| CES3 | carboxylesterase 3 |
| CHST7 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 |
| CIDEC | cell death-inducing DFFA-like effector c |
| COQ6 | coenzyme Q6 monooxygenase |
| CRELD1 | cysteine-rich with EGF-like domains 1 |
| CRY2 | cryptochrome circadian clock 2 |
| CTC1 | CTS telomere maintenance complex component 1 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DGKG | diacylglycerol kinase, gamma 90kDa |
| DHDDS | dehydrodolichyl diphosphate synthase |
| DOK3 | docking protein 3 |
| DPEP2 | dipeptidase 2 |
| EMID1 | EMI domain containing 1 |
| EPHA4 | EPH receptor A4 |
| F13A1 | coagulation factor XIII, A1 polypeptide |
| FAM102A | family with sequence similarity 102, member A |
| FBP1 | fructose-1,6-bisphosphatase 1 |
| FGF23 | fibroblast growth factor 23 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GALE | UDP-galactose-4-epimerase |
| GATA6 | GATA binding protein 6 |
| GJA8 | gap junction protein, alpha 8, 50kDa |
| GRIP2 | glutamate receptor interacting protein 2 |
| HIST1H2BN | histone cluster 1, H2bn |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| HOXC8 | homeobox C8 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IL2 | interleukin 2 |
| IMPDH1 | IMP (inosine 5'-monophosphate) dehydrogenase 1 |
| KLHL21 | kelch-like family member 21 |
| KLHL36 | kelch-like family member 36 |
| LNPEP | leucyl/cystinyl aminopeptidase |
| LY6D | lymphocyte antigen 6 complex, locus D |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MANSC1 | MANSC domain containing 1 |
| MEFV | Mediterranean fever |
| MTHFSD | methenyltetrahydrofolate synthetase domain containing |
| NOTCH4 | notch 4 |
| NXPH4 | neurexophilin 4 |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| OXCT2 | 3-oxoacid CoA transferase 2 |
| P2RY11 | purinergic receptor P2Y, G-protein coupled, 11 |
| PARP3 | poly (ADP-ribose) polymerase family, member 3 |
| PER3 | period circadian clock 3 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 |
| POLH | polymerase (DNA directed), eta |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PRF1 | perforin 1 (pore forming protein) |
| PRSS53 | protease, serine, 53 |
| RAB33A | RAB33A, member RAS oncogene family |
| RAB3A | RAB3A, member RAS oncogene family |
| RHOBTB1 | Rho-related BTB domain containing 1 |
| RIN1 | Ras and Rab interactor 1 |
| RNF121 | ring finger protein 121 |
| SFT2D2 | SFT2 domain containing 2 |
| SH2D4A | SH2 domain containing 4A |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 |
| SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
| SNAI1 | snail family zinc finger 1 |
| SPATA20 | spermatogenesis associated 20 |
| SPATA2L | spermatogenesis associated 2-like |
| SSBP3 | single stranded DNA binding protein 3 |
| STX1A | syntaxin 1A (brain) |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 |
| TOM1 | target of myb1 (chicken) |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| TUBA4B | tubulin, alpha 4b |
| VASH1 | vasohibin 1 |
| VEGFC | vascular endothelial growth factor C |
| WNT16 | wingless-type MMTV integration site family, member 16 |
| XAB2 | XPA binding protein 2 |
| YY2 | YY2 transcription factor |
| ZNF276 | zinc finger protein 276 |
| ZNF34 | zinc finger protein 34 |
| ZNF747 | zinc finger protein 747 |
| ZNF76 | zinc finger protein 76 |
