fluoxetine-3314 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the fluoxetine-3314 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACACB acetyl-CoA carboxylase beta
ALMS1 Alstrom syndrome protein 1
AMPD1 adenosine monophosphate deaminase 1
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARTN artemin
ATM ATM serine/threonine kinase
ATP9A ATPase, class II, type 9A
ATXN2L ataxin 2-like
ATXN7L3B ataxin 7-like 3B
BBS9 Bardet-Biedl syndrome 9
BCL2L10 BCL2-like 10 (apoptosis facilitator)
C1ORF61 chromosome 1 open reading frame 61
CASP2 caspase 2, apoptosis-related cysteine peptidase
CDC14B cell division cycle 14B
CLCN6 chloride channel, voltage-sensitive 6
CLCN7 chloride channel, voltage-sensitive 7
CSF1 colony stimulating factor 1 (macrophage)
CYLD cylindromatosis (turban tumor syndrome)
DCTN1 dynactin 1
DDIT4 DNA-damage-inducible transcript 4
DOC2B double C2-like domains, beta
DSC2 desmocollin 2
DUSP4 dual specificity phosphatase 4
FAM212B family with sequence similarity 212, member B
FLRT2 fibronectin leucine rich transmembrane protein 2
FOXG1 forkhead box G1
FRMD4A FERM domain containing 4A
FSCN1 fascin actin-bundling protein 1
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GAMT guanidinoacetate N-methyltransferase
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HMOX1 heme oxygenase 1
IL6ST interleukin 6 signal transducer
INSIG1 insulin induced gene 1
KCNIP1 Kv channel interacting protein 1
KDM5A lysine (K)-specific demethylase 5A
KLHL22 kelch-like family member 22
KLHL24 kelch-like family member 24
KRT85 keratin 85, type II
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LPCAT4 lysophosphatidylcholine acyltransferase 4
LRP2 low density lipoprotein receptor-related protein 2
LRRC1 leucine rich repeat containing 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MED18 mediator complex subunit 18
MR1 major histocompatibility complex, class I-related
MUC5B mucin 5B, oligomeric mucus/gel-forming
MVK mevalonate kinase
MYT1 myelin transcription factor 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEURL1 neuralized E3 ubiquitin protein ligase 1
NPR3 natriuretic peptide receptor 3
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NUDT7 nudix (nucleoside diphosphate linked moiety X)-type motif 7
OVOL2 ovo-like zinc finger 2
PACS1 phosphofurin acidic cluster sorting protein 1
PARP3 poly (ADP-ribose) polymerase family, member 3
PCDH7 protocadherin 7
PCNXL2 pecanex-like 2 (Drosophila)
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDLIM7 PDZ and LIM domain 7 (enigma)
PGAP3 post-GPI attachment to proteins 3
RAD54L2 RAD54-like 2 (S. cerevisiae)
RBM5 RNA binding motif protein 5
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
RPS11 ribosomal protein S11
RXRB retinoid X receptor, beta
SEZ6L seizure related 6 homolog (mouse)-like
SGK2 serum/glucocorticoid regulated kinase 2
SH2D3A SH2 domain containing 3A
SH3BP2 SH3-domain binding protein 2
SNTG1 syntrophin, gamma 1
SOX10 SRY (sex determining region Y)-box 10
SPN sialophorin
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SREBF2 sterol regulatory element binding transcription factor 2
SRI sorcin
SSPN sarcospan
ST5 suppression of tumorigenicity 5
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TECPR2 tectonin beta-propeller repeat containing 2
TRIM14 tripartite motif containing 14
TUBA4B tubulin, alpha 4b
TYRP1 tyrosinase-related protein 1
UBE2I ubiquitin-conjugating enzyme E2I
USP2 ubiquitin specific peptidase 2
USP36 ubiquitin specific peptidase 36
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
WSB1 WD repeat and SOCS box containing 1
ZNF304 zinc finger protein 304
ZNF76 zinc finger protein 76
ZSCAN12 zinc finger and SCAN domain containing 12
ZSWIM1 zinc finger, SWIM-type containing 1

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ACTG2 actin, gamma 2, smooth muscle, enteric
ACTL8 actin-like 8
ALPK1 alpha-kinase 1
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARMC4 armadillo repeat containing 4
C17ORF70 chromosome 17 open reading frame 70
C6ORF47 chromosome 6 open reading frame 47
CALML5 calmodulin-like 5
CAMK4 calcium/calmodulin-dependent protein kinase IV
CASZ1 castor zinc finger 1
CHRM3 cholinergic receptor, muscarinic 3
CLGN calmegin
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
COPZ2 coatomer protein complex, subunit zeta 2
CTRL chymotrypsin-like
DAGLA diacylglycerol lipase, alpha
EIF4ENIF1 eukaryotic translation initiation factor 4E nuclear import factor 1
ELMO3 engulfment and cell motility 3
EPHA2 EPH receptor A2
EXD3 exonuclease 3'-5' domain containing 3
FADS2 fatty acid desaturase 2
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FKBP10 FK506 binding protein 10, 65 kDa
FKBP1B FK506 binding protein 1B, 12.6 kDa
FOXN2 forkhead box N2
GADD45G growth arrest and DNA-damage-inducible, gamma
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GMPR guanosine monophosphate reductase
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GRB7 growth factor receptor-bound protein 7
H1F0 H1 histone family, member 0
IFI6 interferon, alpha-inducible protein 6
IFT54 intraflagellar transport 54
ITPKB inositol-trisphosphate 3-kinase B
JMJD4 jumonji domain containing 4
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KIAA0754 KIAA0754
LAMP3 lysosomal-associated membrane protein 3
LARP6 La ribonucleoprotein domain family, member 6
LOC730101 uncharacterized LOC730101
LRRC61 leucine rich repeat containing 61
MAP6D1 MAP6 domain containing 1
MAST3 microtubule associated serine/threonine kinase 3
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
NPM3 nucleophosmin/nucleoplasmin 3
NPTX1 neuronal pentraxin I
OCLM oculomedin
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PCDHGB5 protocadherin gamma subfamily B, 5
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PGBD5 piggyBac transposable element derived 5
PGPEP1 pyroglutamyl-peptidase I
PHEX phosphate regulating endopeptidase homolog, X-linked
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLD3 phospholipase D family, member 3
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PTPRU protein tyrosine phosphatase, receptor type, U
RAB30 RAB30, member RAS oncogene family
RAB3A RAB3A, member RAS oncogene family
RNF121 ring finger protein 121
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RPL10L ribosomal protein L10-like
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
RUSC2 RUN and SH3 domain containing 2
SAMHD1 SAM domain and HD domain 1
SCN1B sodium channel, voltage gated, type I beta subunit
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SETD1A SET domain containing 1A
SETD8 SET domain containing (lysine methyltransferase) 8
SIDT1 SID1 transmembrane family, member 1
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SLN sarcolipin
SLPI secretory leukocyte peptidase inhibitor
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SNAI2 snail family zinc finger 2
SPAG7 sperm associated antigen 7
SPON2 spondin 2, extracellular matrix protein
STAB2 stabilin 2
STRA6 stimulated by retinoic acid 6
TCTN2 tectonic family member 2
TLN1 talin 1
TMEM104 transmembrane protein 104
TMEM120B transmembrane protein 120B
TMEM254 transmembrane protein 254
VGF VGF nerve growth factor inducible
WDR62 WD repeat domain 62
ZBED1 zinc finger, BED-type containing 1
ZBTB44 zinc finger and BTB domain containing 44
ZNF516 zinc finger protein 516
ZNF696 zinc finger protein 696