| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the fluoxetine-5356 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACSL4 | acyl-CoA synthetase long-chain family member 4 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
| AHI1 | Abelson helper integration site 1 |
| APOC1 | apolipoprotein C-I |
| APOL2 | apolipoprotein L, 2 |
| ARC | activity-regulated cytoskeleton-associated protein |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 |
| ARL2BP | ADP-ribosylation factor-like 2 binding protein |
| ATF3 | activating transcription factor 3 |
| BAIAP2 | BAI1-associated protein 2 |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| CACNB3 | calcium channel, voltage-dependent, beta 3 subunit |
| CACTIN | cactin, spliceosome C complex subunit |
| CCNG2 | cyclin G2 |
| CDC42EP2 | CDC42 effector protein (Rho GTPase binding) 2 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A |
| CES3 | carboxylesterase 3 |
| CHKB | choline kinase beta |
| CHPF2 | chondroitin polymerizing factor 2 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DUSP1 | dual specificity phosphatase 1 |
| DUSP10 | dual specificity phosphatase 10 |
| DUSP4 | dual specificity phosphatase 4 |
| EGR1 | early growth response 1 |
| EGR3 | early growth response 3 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 |
| FAM189A2 | family with sequence similarity 189, member A2 |
| FAM46C | family with sequence similarity 46, member C |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
| FOSL1 | FOS-like antigen 1 |
| FOSL2 | FOS-like antigen 2 |
| FRMD4B | FERM domain containing 4B |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GDPD5 | glycerophosphodiester phosphodiesterase domain containing 5 |
| HEG1 | heart development protein with EGF-like domains 1 |
| HIST1H2BJ | histone cluster 1, H2bj |
| HRK | harakiri, BCL2 interacting protein |
| HSD17B7 | hydroxysteroid (17-beta) dehydrogenase 7 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
| INHBA | inhibin, beta A |
| INSIG1 | insulin induced gene 1 |
| INSR | insulin receptor |
| JUN | jun proto-oncogene |
| JUND | jun D proto-oncogene |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KDM5A | lysine (K)-specific demethylase 5A |
| KLF2 | Kruppel-like factor 2 |
| KLF3 | Kruppel-like factor 3 (basic) |
| KLF6 | Kruppel-like factor 6 |
| LAMA3 | laminin, alpha 3 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
| LPIN1 | lipin 1 |
| LRRC61 | leucine rich repeat containing 61 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MMP25 | matrix metallopeptidase 25 |
| MT1F | metallothionein 1F |
| MVD | mevalonate (diphospho) decarboxylase |
| MYCL | v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 |
| NF2 | neurofibromin 2 (merlin) |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| PAX5 | paired box 5 |
| PCNX | pecanex homolog (Drosophila) |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PPP6R2 | protein phosphatase 6, regulatory subunit 2 |
| PRR4 | proline rich 4 (lacrimal) |
| RAB11FIP3 | RAB11 family interacting protein 3 (class II) |
| RAB8B | RAB8B, member RAS oncogene family |
| RBL2 | retinoblastoma-like 2 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SH3BP2 | SH3-domain binding protein 2 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SOCS1 | suppressor of cytokine signaling 1 |
| SPTLC2 | serine palmitoyltransferase, long chain base subunit 2 |
| SREBF2 | sterol regulatory element binding transcription factor 2 |
| TET3 | tet methylcytosine dioxygenase 3 |
| TLE4 | transducin-like enhancer of split 4 |
| TMEM104 | transmembrane protein 104 |
| TMEM80 | transmembrane protein 80 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TRIM2 | tripartite motif containing 2 |
| TSKU | tsukushi, small leucine rich proteoglycan |
| USB1 | U6 snRNA biogenesis 1 |
| ZBTB17 | zinc finger and BTB domain containing 17 |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZNF16 | zinc finger protein 16 |
| ZNF750 | zinc finger protein 750 |
| Symbol | Name |
|---|---|
| ABCC6 | ATP-binding cassette, sub-family C (CFTR/MRP), member 6 |
| ACAD8 | acyl-CoA dehydrogenase family, member 8 |
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| ADRA2C | adrenoceptor alpha 2C |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ARNTL2 | aryl hydrocarbon receptor nuclear translocator-like 2 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C17ORF70 | chromosome 17 open reading frame 70 |
| C1ORF56 | chromosome 1 open reading frame 56 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CA11 | carbonic anhydrase XI |
| CAPN15 | calpain 15 |
| CCP110 | centriolar coiled coil protein 110kDa |
| CISH | cytokine inducible SH2-containing protein |
| CWC25 | CWC25 spliceosome-associated protein homolog (S. cerevisiae) |
| DENND4A | DENN/MADD domain containing 4A |
| DLEU2 | deleted in lymphocytic leukemia 2 (non-protein coding) |
| EFNA3 | ephrin-A3 |
| ELP4 | elongator acetyltransferase complex subunit 4 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 |
| FAM222B | family with sequence similarity 222, member B |
| FASTKD5 | FAST kinase domains 5 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FKTN | fukutin |
| GDAP1 | ganglioside induced differentiation associated protein 1 |
| GLI3 | GLI family zinc finger 3 |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| HAUS6 | HAUS augmin-like complex, subunit 6 |
| HIST1H1D | histone cluster 1, H1d |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IFI6 | interferon, alpha-inducible protein 6 |
| INPP5A | inositol polyphosphate-5-phosphatase, 40kDa |
| KDM5C | lysine (K)-specific demethylase 5C |
| KIAA1551 | KIAA1551 |
| KIFC1 | kinesin family member C1 |
| KRBOX4 | KRAB box domain containing 4 |
| KRCC1 | lysine-rich coiled-coil 1 |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LMNB1 | lamin B1 |
| LNPEP | leucyl/cystinyl aminopeptidase |
| LOC730101 | uncharacterized LOC730101 |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 |
| LRRC8E | leucine rich repeat containing 8 family, member E |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| MEFV | Mediterranean fever |
| MPI | mannose phosphate isomerase |
| MPP6 | membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6) |
| MVP | major vault protein |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NUBPL | nucleotide binding protein-like |
| ORC2 | origin recognition complex, subunit 2 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PARPBP | PARP1 binding protein |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PLXNA3 | plexin A3 |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PTDSS2 | phosphatidylserine synthase 2 |
| PTK6 | protein tyrosine kinase 6 |
| RABL6 | RAB, member RAS oncogene family-like 6 |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RBM42 | RNA binding motif protein 42 |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RNF121 | ring finger protein 121 |
| RNF2 | ring finger protein 2 |
| RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| SEH1L | SEH1-like (S. cerevisiae) |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SLC16A6 | solute carrier family 16, member 6 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC46A3 | solute carrier family 46, member 3 |
| SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
| SOBP | sine oculis binding protein homolog (Drosophila) |
| SUGP1 | SURP and G patch domain containing 1 |
| SYCP2 | synaptonemal complex protein 2 |
| THNSL1 | threonine synthase-like 1 (S. cerevisiae) |
| TMEM38B | transmembrane protein 38B |
| TNNT1 | troponin T type 1 (skeletal, slow) |
| TPRA1 | transmembrane protein, adipocyte asscociated 1 |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| TUBA3C | tubulin, alpha 3c |
| VAV1 | vav 1 guanine nucleotide exchange factor |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) |
| WDR76 | WD repeat domain 76 |
| XK | X-linked Kx blood group |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| ZNF227 | zinc finger protein 227 |
| ZNF273 | zinc finger protein 273 |
| ZNF365 | zinc finger protein 365 |
| ZNF573 | zinc finger protein 573 |
| ZNF586 | zinc finger protein 586 |
| ZNF692 | zinc finger protein 692 |
| ZNF701 | zinc finger protein 701 |
| ZNF83 | zinc finger protein 83 |
