| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the fluoxetine-6757 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACOXL | acyl-CoA oxidase-like |
| ADRA2C | adrenoceptor alpha 2C |
| ALOX5 | arachidonate 5-lipoxygenase |
| ASCL1 | achaete-scute family bHLH transcription factor 1 |
| B3GAT1 | beta-1,3-glucuronyltransferase 1 |
| BAAT | bile acid CoA:amino acid N-acyltransferase |
| BCL2 | B-cell CLL/lymphoma 2 |
| BDKRB1 | bradykinin receptor B1 |
| BLK | BLK proto-oncogene, Src family tyrosine kinase |
| BMP7 | bone morphogenetic protein 7 |
| BTN3A1 | butyrophilin, subfamily 3, member A1 |
| C1ORF54 | chromosome 1 open reading frame 54 |
| C8ORF4 | chromosome 8 open reading frame 4 |
| CCL22 | chemokine (C-C motif) ligand 22 |
| CHRNA4 | cholinergic receptor, nicotinic, alpha 4 (neuronal) |
| CNKSR2 | connector enhancer of kinase suppressor of Ras 2 |
| DCTN1 | dynactin 1 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 |
| DPT | dermatopontin |
| DPY19L1P1 | DPY19L1 pseudogene 1 |
| DRD1 | dopamine receptor D1 |
| DRP2 | dystrophin related protein 2 |
| DYRK1B | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B |
| ECM1 | extracellular matrix protein 1 |
| EFS | embryonal Fyn-associated substrate |
| EGR4 | early growth response 4 |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 |
| ESR1 | estrogen receptor 1 |
| FLJ11292 | |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GAL3ST1 | galactose-3-O-sulfotransferase 1 |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) |
| GNRH1 | gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) |
| GRIK3 | glutamate receptor, ionotropic, kainate 3 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| HBB | hemoglobin, beta |
| HFE | hemochromatosis |
| HNF1B | HNF1 homeobox B |
| HTR1D | 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled |
| IFFO1 | intermediate filament family orphan 1 |
| ING4 | inhibitor of growth family, member 4 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
| ITPK1 | inositol-tetrakisphosphate 1-kinase |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KIAA1467 | KIAA1467 |
| KLF1 | Kruppel-like factor 1 (erythroid) |
| LIPG | lipase, endothelial |
| LMOD1 | leiomodin 1 (smooth muscle) |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 |
| MIA2 | melanoma inhibitory activity 2 |
| MMP9 | matrix metallopeptidase 9 |
| MORN1 | MORN repeat containing 1 |
| MRPL41 | mitochondrial ribosomal protein L41 |
| MST1 | macrophage stimulating 1 |
| MYOM1 | myomesin 1 |
| MYRF | myelin regulatory factor |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NRG1 | neuregulin 1 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| PACRG | PARK2 co-regulated |
| PADI4 | peptidyl arginine deiminase, type IV |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 |
| PAOX | polyamine oxidase (exo-N4-amino) |
| PDE3B | phosphodiesterase 3B, cGMP-inhibited |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PDPN | podoplanin |
| PGF | placental growth factor |
| PNMAL1 | paraneoplastic Ma antigen family-like 1 |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) |
| PPP1R16B | protein phosphatase 1, regulatory subunit 16B |
| PRKCA | protein kinase C, alpha |
| PSG3 | pregnancy specific beta-1-glycoprotein 3 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 |
| PTPRH | protein tyrosine phosphatase, receptor type, H |
| RERE | arginine-glutamic acid dipeptide (RE) repeats |
| RIMS1 | regulating synaptic membrane exocytosis 1 |
| RIN3 | Ras and Rab interactor 3 |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) |
| RPS3A | ribosomal protein S3A |
| SDHD | succinate dehydrogenase complex, subunit D, integral membrane protein |
| SH3BP2 | SH3-domain binding protein 2 |
| SLC16A4 | solute carrier family 16, member 4 |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SLC7A9 | solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SNED1 | sushi, nidogen and EGF-like domains 1 |
| SRD5A2 | steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) |
| ST8SIA3 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 |
| TBL1Y | transducin (beta)-like 1, Y-linked |
| TCL6 | T-cell leukemia/lymphoma 6 (non-protein coding) |
| TEX11 | testis expressed 11 |
| THOC5 | THO complex 5 |
| TK2 | thymidine kinase 2, mitochondrial |
| TMPRSS4 | transmembrane protease, serine 4 |
| TSKS | testis-specific serine kinase substrate |
| ZNF93 | zinc finger protein 93 |
| ZNRF4 | zinc and ring finger 4 |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 |
| Symbol | Name |
|---|---|
| ABCB8 | ATP-binding cassette, sub-family B (MDR/TAP), member 8 |
| ABHD17B | abhydrolase domain containing 17B |
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| ADCY6 | adenylate cyclase 6 |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| ANXA2P1 | annexin A2 pseudogene 1 |
| APOC4 | apolipoprotein C-IV |
| APOL6 | apolipoprotein L, 6 |
| ARMCX4 | armadillo repeat containing, X-linked 4 |
| ASIC1 | acid sensing (proton gated) ion channel 1 |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 |
| C1RL | complement component 1, r subcomponent-like |
| C9ORF40 | chromosome 9 open reading frame 40 |
| CCNJ | cyclin J |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CDON | cell adhesion associated, oncogene regulated |
| CLDN15 | claudin 15 |
| CNTNAP3B | contactin associated protein-like 3B |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| CYP7B1 | cytochrome P450, family 7, subfamily B, polypeptide 1 |
| DNM3 | dynamin 3 |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| EFNA3 | ephrin-A3 |
| EFNA4 | ephrin-A4 |
| EPHA7 | EPH receptor A7 |
| EPHX2 | epoxide hydrolase 2, cytoplasmic |
| ERMP1 | endoplasmic reticulum metallopeptidase 1 |
| FBRS | fibrosin |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FGL1 | fibrinogen-like 1 |
| FMO4 | flavin containing monooxygenase 4 |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| FRMD8 | FERM domain containing 8 |
| FRS2 | fibroblast growth factor receptor substrate 2 |
| FZD3 | frizzled class receptor 3 |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
| GMPR | guanosine monophosphate reductase |
| GREB1L | growth regulation by estrogen in breast cancer-like |
| GUF1 | GUF1 GTPase homolog (S. cerevisiae) |
| HIST1H2AJ | histone cluster 1, H2aj |
| HOOK1 | hook microtubule-tethering protein 1 |
| HOXA1 | homeobox A1 |
| HOXA7 | homeobox A7 |
| HSPA1L | heat shock 70kDa protein 1-like |
| IBA57 | IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae) |
| IFI6 | interferon, alpha-inducible protein 6 |
| LIFR | leukemia inhibitory factor receptor alpha |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LRRC37A4P | leucine rich repeat containing 37, member A4, pseudogene |
| MANBA | mannosidase, beta A, lysosomal |
| ME3 | malic enzyme 3, NADP(+)-dependent, mitochondrial |
| MED15 | mediator complex subunit 15 |
| MED9 | mediator complex subunit 9 |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 |
| MMP13 | matrix metallopeptidase 13 |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MTMR12 | myotubularin related protein 12 |
| NEUROD1 | neuronal differentiation 1 |
| NPR3 | natriuretic peptide receptor 3 |
| NUP62CL | nucleoporin 62kDa C-terminal like |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PDE8B | phosphodiesterase 8B |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 |
| PKD2L2 | polycystic kidney disease 2-like 2 |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PRAMEF10 | PRAME family member 10 |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| PRF1 | perforin 1 (pore forming protein) |
| PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit |
| PWAR5 | Prader Willi/Angelman region RNA 5 |
| RABL6 | RAB, member RAS oncogene family-like 6 |
| RECQL4 | RecQ protein-like 4 |
| RPGRIP1L | RPGRIP1-like |
| RUNX1-IT1 | RUNX1 intronic transcript 1 |
| SCEL | sciellin |
| SCN8A | sodium channel, voltage gated, type VIII alpha subunit |
| SPRYD7 | SPRY domain containing 7 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 |
| TESK2 | testis-specific kinase 2 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TLR2 | toll-like receptor 2 |
| TMEM242 | transmembrane protein 242 |
| TWISTNB | TWIST neighbor |
| USP8 | ubiquitin specific peptidase 8 |
| VGF | VGF nerve growth factor inducible |
| YOD1 | YOD1 deubiquitinase |
| ZNF10 | zinc finger protein 10 |
| ZNF324 | zinc finger protein 324 |
| ZNF350 | zinc finger protein 350 |
| ZNF442 | zinc finger protein 442 |
| ZNF446 | zinc finger protein 446 |
| ZNF480 | zinc finger protein 480 |
| ZNF675 | zinc finger protein 675 |
