flupentixol-1288 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the flupentixol-1288 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ADCY9 adenylate cyclase 9
ADGRL3 adhesion G protein-coupled receptor L3
AHCYL1 adenosylhomocysteinase-like 1
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)
APOE apolipoprotein E
AREG amphiregulin
ARHGAP33 Rho GTPase activating protein 33
ARHGAP35 Rho GTPase activating protein 35
ARL1 ADP-ribosylation factor-like 1
ARR3 arrestin 3, retinal (X-arrestin)
ATAT1 alpha tubulin acetyltransferase 1
ATP13A2 ATPase type 13A2
BAHCC1 BAH domain and coiled-coil containing 1
BRD4 bromodomain containing 4
C21ORF2 chromosome 21 open reading frame 2
C22ORF29 chromosome 22 open reading frame 29
C2CD2L C2CD2-like
C3ORF18 chromosome 3 open reading frame 18
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family)
CEP41 centrosomal protein 41kDa
CGREF1 cell growth regulator with EF-hand domain 1
CHD3 chromodomain helicase DNA binding protein 3
CLSPN claspin
COQ7 coenzyme Q7 homolog, ubiquinone (yeast)
DGAT1 diacylglycerol O-acyltransferase 1
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DVL2 dishevelled segment polarity protein 2
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
ERMAP erythroblast membrane-associated protein (Scianna blood group)
F13A1 coagulation factor XIII, A1 polypeptide
FAM102A family with sequence similarity 102, member A
FAM114A1 family with sequence similarity 114, member A1
FAM160B2 family with sequence similarity 160, member B2
FBXO11 F-box protein 11
FLNB filamin B, beta
FMOD fibromodulin
FZD7 frizzled class receptor 7
GABARAPL1 GABA(A) receptor-associated protein like 1
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GEM GTP binding protein overexpressed in skeletal muscle
GLG1 golgi glycoprotein 1
HMOX2 heme oxygenase 2
HRAS Harvey rat sarcoma viral oncogene homolog
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
IL1RAP interleukin 1 receptor accessory protein
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
INF2 inverted formin, FH2 and WH2 domain containing
KCTD13 potassium channel tetramerization domain containing 13
KCTD2 potassium channel tetramerization domain containing 2
LPAR2 lysophosphatidic acid receptor 2
MAGED2 melanoma antigen family D2
MAGEF1 melanoma antigen family F1
MAP4 microtubule-associated protein 4
METRN meteorin, glial cell differentiation regulator
NDRG3 NDRG family member 3
NIPAL2 NIPA-like domain containing 2
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae)
NRCAM neuronal cell adhesion molecule
NT5DC3 5'-nucleotidase domain containing 3
PAPOLA poly(A) polymerase alpha
PBX2 pre-B-cell leukemia homeobox 2
PDE4DIP phosphodiesterase 4D interacting protein
PDE8A phosphodiesterase 8A
PIPOX pipecolic acid oxidase
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLK3 polo-like kinase 3
PML promyelocytic leukemia
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
PROCR protein C receptor, endothelial
RAP1GAP RAP1 GTPase activating protein
RECQL5 RecQ protein-like 5
RNF126P1 ring finger protein 126 pseudogene 1
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2
RRP1B ribosomal RNA processing 1B
RTEL1 regulator of telomere elongation helicase 1
SCARB2 scavenger receptor class B, member 2
SIGLEC7 sialic acid binding Ig-like lectin 7
SIRT5 sirtuin 5
SLC19A1 solute carrier family 19 (folate transporter), member 1
SPAG4 sperm associated antigen 4
SPIDR scaffolding protein involved in DNA repair
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STIM1 stromal interaction molecule 1
STXBP6 syntaxin binding protein 6 (amisyn)
SUGP1 SURP and G patch domain containing 1
TECPR2 tectonin beta-propeller repeat containing 2
TGFBR3 transforming growth factor, beta receptor III
TLE4 transducin-like enhancer of split 4
TMEM180 transmembrane protein 180
TMEM53 transmembrane protein 53
TTC38 tetratricopeptide repeat domain 38
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
ZC4H2 zinc finger, C4H2 domain containing
ZNF286A zinc finger protein 286A
ZNF34 zinc finger protein 34
ZNF668 zinc finger protein 668

decreased expression

Symbol Name
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5
ACVR2B activin A receptor, type IIB
ADAM10 ADAM metallopeptidase domain 10
ANKRD36 ankyrin repeat domain 36
AP1G1 adaptor-related protein complex 1, gamma 1 subunit
ASAP1-IT1 ASAP1 intronic transcript 1
ASB8 ankyrin repeat and SOCS box containing 8
ATAD5 ATPase family, AAA domain containing 5
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
C11ORF68 chromosome 11 open reading frame 68
C2CD2 C2 calcium-dependent domain containing 2
CAPG capping protein (actin filament), gelsolin-like
CCL2 chemokine (C-C motif) ligand 2
CCNT1 cyclin T1
CCRL2 chemokine (C-C motif) receptor-like 2
CGGBP1 CGG triplet repeat binding protein 1
CHKB choline kinase beta
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
CPNE1 copine I
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
DCAF16 DDB1 and CUL4 associated factor 16
DEPDC1 DEP domain containing 1
DYM dymeclin
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
ERAP2 endoplasmic reticulum aminopeptidase 2
EXOC5 exocyst complex component 5
FAM222B family with sequence similarity 222, member B
FES FES proto-oncogene, tyrosine kinase
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GAB2 GRB2-associated binding protein 2
GNL2 guanine nucleotide binding protein-like 2 (nucleolar)
GSTCD glutathione S-transferase, C-terminal domain containing
HCFC2 host cell factor C2
HELLS helicase, lymphoid-specific
IGFLR1 IGF-like family receptor 1
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KIF18A kinesin family member 18A
KRBOX4 KRAB box domain containing 4
LAX1 lymphocyte transmembrane adaptor 1
LMAN1 lectin, mannose-binding, 1
LMNB1 lamin B1
LOC100127972 uncharacterized LOC100127972
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAGT1 magnesium transporter 1
MAVS mitochondrial antiviral signaling protein
MBTD1 mbt domain containing 1
MICALL2 MICAL-like 2
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit
NIP7 NIP7, nucleolar pre-rRNA processing protein
NME6 NME/NM23 nucleoside diphosphate kinase 6
NRGN neurogranin (protein kinase C substrate, RC3)
NRIP3 nuclear receptor interacting protein 3
NT5E 5'-nucleotidase, ecto (CD73)
ODF2 outer dense fiber of sperm tails 2
PAK1IP1 PAK1 interacting protein 1
PAQR6 progestin and adipoQ receptor family member VI
PCYOX1 prenylcysteine oxidase 1
PHKG2 phosphorylase kinase, gamma 2 (testis)
PIGA phosphatidylinositol glycan anchor biosynthesis, class A
PILRB paired immunoglobin-like type 2 receptor beta
PLAG1 pleiomorphic adenoma gene 1
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PLEKHO1 pleckstrin homology domain containing, family O member 1
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2
PPP6R3 protein phosphatase 6, regulatory subunit 3
PRRC1 proline-rich coiled-coil 1
RBM42 RNA binding motif protein 42
RFX7 regulatory factor X, 7
RPAP2 RNA polymerase II associated protein 2
RSRC1 arginine/serine-rich coiled-coil 1
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
SKI SKI proto-oncogene
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SMURF2 SMAD specific E3 ubiquitin protein ligase 2
SNORA21 small nucleolar RNA, H/ACA box 21
SP140L SP140 nuclear body protein-like
SREK1IP1 SREK1-interacting protein 1
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
THOC1 THO complex 1
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TMEM184C transmembrane protein 184C
TMEM260 transmembrane protein 260
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TUBA3C tubulin, alpha 3c
WDR5B WD repeat domain 5B
WWC2 WW and C2 domain containing 2
ZC2HC1A zinc finger, C2HC-type containing 1A
ZNF12 zinc finger protein 12
ZNF124 zinc finger protein 124
ZNF136 zinc finger protein 136