flupentixol-5307 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the flupentixol-5307 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGRG1 adhesion G protein-coupled receptor G1
APP amyloid beta (A4) precursor protein
AQP3 aquaporin 3 (Gill blood group)
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
BBS9 Bardet-Biedl syndrome 9
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C2ORF27A chromosome 2 open reading frame 27A
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCNG2 cyclin G2
CD44 CD44 molecule (Indian blood group)
CDK3 cyclin-dependent kinase 3
CDYL chromodomain protein, Y-like
CEMIP cell migration inducing protein, hyaluronan binding
CERK ceramide kinase
CGA glycoprotein hormones, alpha polypeptide
CHKB choline kinase beta
CLPTM1 cleft lip and palate associated transmembrane protein 1
CRABP1 cellular retinoic acid binding protein 1
CRELD1 cysteine-rich with EGF-like domains 1
CRIP1 cysteine-rich protein 1 (intestinal)
CUL4B cullin 4B
CYHR1 cysteine/histidine-rich 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DST dystonin
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene
DUSP4 dual specificity phosphatase 4
E2F4 E2F transcription factor 4, p107/p130-binding
EFNA3 ephrin-A3
EGFR epidermal growth factor receptor
ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 (putative)
ESR1 estrogen receptor 1
ETAA1 Ewing tumor-associated antigen 1
F3 coagulation factor III (thromboplastin, tissue factor)
FAM189A2 family with sequence similarity 189, member A2
FZD7 frizzled class receptor 7
GAMT guanidinoacetate N-methyltransferase
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GSK3A glycogen synthase kinase 3 alpha
GSTM2 glutathione S-transferase mu 2 (muscle)
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4
HLA-C major histocompatibility complex, class I, C
HPS1 Hermansky-Pudlak syndrome 1
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
IFT140 intraflagellar transport 140
IL17RA interleukin 17 receptor A
IL27RA interleukin 27 receptor, alpha
INO80D INO80 complex subunit D
IRS2 insulin receptor substrate 2
JRK Jrk homolog (mouse)
KDM2A lysine (K)-specific demethylase 2A
KDM5A lysine (K)-specific demethylase 5A
KLHL22 kelch-like family member 22
LARP6 La ribonucleoprotein domain family, member 6
LPIN1 lipin 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAPK3 mitogen-activated protein kinase 3
MAPK7 mitogen-activated protein kinase 7
MAZ MYC-associated zinc finger protein (purine-binding transcription factor)
MED28 mediator complex subunit 28
MMP19 matrix metallopeptidase 19
MRPS12 mitochondrial ribosomal protein S12
MVD mevalonate (diphospho) decarboxylase
PAM peptidylglycine alpha-amidating monooxygenase
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDGFB platelet-derived growth factor beta polypeptide
PHLDA1 pleckstrin homology-like domain, family A, member 1
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PLEC plectin
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLEKHO1 pleckstrin homology domain containing, family O member 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PTPRF protein tyrosine phosphatase, receptor type, F
RAB6A RAB6A, member RAS oncogene family
RARA retinoic acid receptor, alpha
RNF6 ring finger protein (C3H2C3 type) 6
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
S100A4 S100 calcium binding protein A4
SCN1B sodium channel, voltage gated, type I beta subunit
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SPTBN1 spectrin, beta, non-erythrocytic 1
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STC1 stanniocalcin 1
SUGP1 SURP and G patch domain containing 1
SUPT7L suppressor of Ty 7 (S. cerevisiae)-like
SYBU syntabulin (syntaxin-interacting)
TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
TCP11L1 t-complex 11, testis-specific-like 1
TUBGCP2 tubulin, gamma complex associated protein 2
UBE3A ubiquitin protein ligase E3A
WWOX WW domain containing oxidoreductase
YTHDC1 YTH domain containing 1
ZER1 zyg-11 related, cell cycle regulator
ZFPL1 zinc finger protein-like 1
ZNF688 zinc finger protein 688

decreased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ACADSB acyl-CoA dehydrogenase, short/branched chain
ADPGK ADP-dependent glucokinase
ALG6 ALG6, alpha-1,3-glucosyltransferase
ANKRD36 ankyrin repeat domain 36
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
APH1A APH1A gamma secretase subunit
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARL15 ADP-ribosylation factor-like 15
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
AXIN1 axin 1
BAX BCL2-associated X protein
BPGM 2,3-bisphosphoglycerate mutase
BRD9 bromodomain containing 9
C19ORF40 chromosome 19 open reading frame 40
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
CCDC92 coiled-coil domain containing 92
CEP192 centrosomal protein 192kDa
CFD complement factor D (adipsin)
CIT citron rho-interacting serine/threonine kinase
CLSPN claspin
COMMD10 COMM domain containing 10
CORO1A coronin, actin binding protein, 1A
CUEDC1 CUE domain containing 1
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DLEU2 deleted in lymphocytic leukemia 2 (non-protein coding)
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
DVL1 dishevelled segment polarity protein 1
DZANK1 double zinc ribbon and ankyrin repeat domains 1
ECHDC3 enoyl CoA hydratase domain containing 3
EFHD1 EF-hand domain family, member D1
ERCC8 excision repair cross-complementation group 8
F8 coagulation factor VIII, procoagulant component
FAM50B family with sequence similarity 50, member B
FAM86B1 family with sequence similarity 86, member B1
FGD6 FYVE, RhoGEF and PH domain containing 6
FGGY FGGY carbohydrate kinase domain containing
FKBPL FK506 binding protein like
FPGT fucose-1-phosphate guanylyltransferase
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GAR1 GAR1 ribonucleoprotein
GATAD2A GATA zinc finger domain containing 2A
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GPR19 G protein-coupled receptor 19
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
GUSBP3 glucuronidase, beta pseudogene 3
GYS1 glycogen synthase 1 (muscle)
HIRA histone cell cycle regulator
HPSE heparanase
IFI6 interferon, alpha-inducible protein 6
IGFLR1 IGF-like family receptor 1
IMPACT impact RWD domain protein
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
KATNBL1 katanin p80 subunit B-like 1
KIFAP3 kinesin-associated protein 3
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LINS lines homolog (Drosophila)
LMNB1 lamin B1
LOC390998 ribosomal protein L10 pseudogene
MAPKBP1 mitogen-activated protein kinase binding protein 1
MEIS2 Meis homeobox 2
METTL8 methyltransferase like 8
MITF microphthalmia-associated transcription factor
MKNK2 MAP kinase interacting serine/threonine kinase 2
MLYCD malonyl-CoA decarboxylase
MMD monocyte to macrophage differentiation-associated
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MRPL44 mitochondrial ribosomal protein L44
MRPL52 mitochondrial ribosomal protein L52
N6AMT1 N-6 adenine-specific DNA methyltransferase 1 (putative)
NFS1 NFS1 cysteine desulfurase
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
PRSS22 protease, serine, 22
QTRT1 queuine tRNA-ribosyltransferase 1
SH3BGR SH3 domain binding glutamate-rich protein
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SLC9A6 solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6
STBD1 starch binding domain 1
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative)
TMC7 transmembrane channel-like 7
TMEM184C transmembrane protein 184C
TPCN1 two pore segment channel 1
TUBA3C tubulin, alpha 3c
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2
UROS uroporphyrinogen III synthase
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast)
WDR46 WD repeat domain 46
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZNF180 zinc finger protein 180
ZNF211 zinc finger protein 211
ZNF282 zinc finger protein 282
ZNF35 zinc finger protein 35
ZNF611 zinc finger protein 611