flupentixol-6708 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the flupentixol-6708 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACOT11 acyl-CoA thioesterase 11
ADAM22 ADAM metallopeptidase domain 22
ADARB1 adenosine deaminase, RNA-specific, B1
ADGRF5 adhesion G protein-coupled receptor F5
ADRA2B adrenoceptor alpha 2B
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ALOX12B arachidonate 12-lipoxygenase, 12R type
AQP4 aquaporin 4
ARHGAP28 Rho GTPase activating protein 28
ASNS asparagine synthetase (glutamine-hydrolyzing)
BAIAP3 BAI1-associated protein 3
BTG2 BTG family, member 2
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
CBS cystathionine-beta-synthase
CD300C CD300c molecule
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal)
CLDN17 claudin 17
CNGB3 cyclic nucleotide gated channel beta 3
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2
COBL cordon-bleu WH2 repeat protein
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CRTAC1 cartilage acidic protein 1
CTNS cystinosin, lysosomal cystine transporter
DAPK3 death-associated protein kinase 3
DDIT4 DNA-damage-inducible transcript 4
DDO D-aspartate oxidase
DLC1 DLC1 Rho GTPase activating protein
ERO1LB ERO1-like beta (S. cerevisiae)
FAM63A family with sequence similarity 63, member A
FBXO31 F-box protein 31
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FGB fibrinogen beta chain
FSCN3 fascin actin-bundling protein 3, testicular
GIMAP5 GTPase, IMAP family member 5
GK3P glycerol kinase 3 pseudogene
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HPN hepsin
HPX hemopexin
IMPG2 interphotoreceptor matrix proteoglycan 2
ITPKA inositol-trisphosphate 3-kinase A
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KIAA1467 KIAA1467
KLF9 Kruppel-like factor 9
KRT17 keratin 17, type I
LRP2 low density lipoprotein receptor-related protein 2
MED25 mediator complex subunit 25
MEFV Mediterranean fever
MT1M metallothionein 1M
MTMR7 myotubularin related protein 7
MYEF2 myelin expression factor 2
MYH3 myosin, heavy chain 3, skeletal muscle, embryonic
NIPAL2 NIPA-like domain containing 2
NIPSNAP3B nipsnap homolog 3B (C. elegans)
NNMT nicotinamide N-methyltransferase
NRXN3 neurexin 3
NUPR1 nuclear protein, transcriptional regulator, 1
OSGIN2 oxidative stress induced growth inhibitor family member 2
OVOL2 ovo-like zinc finger 2
PDE11A phosphodiesterase 11A
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PDIA2 protein disulfide isomerase family A, member 2
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
PGP phosphoglycolate phosphatase
PHF2 PHD finger protein 2
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PRDM11 PR domain containing 11
PRR5 proline rich 5 (renal)
PURA purine-rich element binding protein A
RALGPS1 Ral GEF with PH domain and SH3 binding motif 1
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RGS4 regulator of G-protein signaling 4
RGS5 regulator of G-protein signaling 5
RHOT2 ras homolog family member T2
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RPH3AL rabphilin 3A-like (without C2 domains)
RPL10 ribosomal protein L10
RPL10L ribosomal protein L10-like
RPS4Y1 ribosomal protein S4, Y-linked 1
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
SLAMF7 SLAM family member 7
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3
SQSTM1 sequestosome 1
SRPX2 sushi-repeat containing protein, X-linked 2
STK17A serine/threonine kinase 17a
SYT1 synaptotagmin I
SYT12 synaptotagmin XII
THSD4 thrombospondin, type I, domain containing 4
TRIB3 tribbles pseudokinase 3
TSC22D3 TSC22 domain family, member 3
WIPI1 WD repeat domain, phosphoinositide interacting 1
ZBTB20 zinc finger and BTB domain containing 20
ZNF219 zinc finger protein 219

decreased expression

Symbol Name
AGMAT agmatine ureohydrolase (agmatinase)
ANP32A-IT1 ANP32A intronic transcript 1
APLP1 amyloid beta (A4) precursor-like protein 1
ARHGAP10 Rho GTPase activating protein 10
ASAP1-IT1 ASAP1 intronic transcript 1
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ATAD5 ATPase family, AAA domain containing 5
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
BRIP1 BRCA1 interacting protein C-terminal helicase 1
BTC betacellulin
C14ORF93 chromosome 14 open reading frame 93
CCNJ cyclin J
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CD70 CD70 molecule
CDC7 cell division cycle 7
CDK6 cyclin-dependent kinase 6
CENPJ centromere protein J
CHM choroideremia (Rab escort protein 1)
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CINP cyclin-dependent kinase 2 interacting protein
CLDN11 claudin 11
CORT cortistatin
DAGLA diacylglycerol lipase, alpha
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DBF4B DBF4 zinc finger B
DDN dendrin
DENND5B DENN/MADD domain containing 5B
DNAH7 dynein, axonemal, heavy chain 7
DNAL4 dynein, axonemal, light chain 4
EFNB1 ephrin-B1
ELP6 elongator acetyltransferase complex subunit 6
FBRS fibrosin
GJC1 gap junction protein, gamma 1, 45kDa
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GSTA3 glutathione S-transferase alpha 3
GUSBP3 glucuronidase, beta pseudogene 3
HAMP hepcidin antimicrobial peptide
HELLS helicase, lymphoid-specific
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIRA histone cell cycle regulator
HIST1H2BN histone cluster 1, H2bn
HIST1H3A histone cluster 1, H3a
HIST1H4E histone cluster 1, H4e
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HMHA1 histocompatibility (minor) HA-1
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HOXA4 homeobox A4
HOXA7 homeobox A7
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IPO8 importin 8
KIAA1456 KIAA1456
KIAA1549L KIAA1549-like
KPNA5 karyopherin alpha 5 (importin alpha 6)
LRRC37A3 leucine rich repeat containing 37, member A3
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MGC12488
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MRPL41 mitochondrial ribosomal protein L41
MRPS18C mitochondrial ribosomal protein S18C
MTHFSD methenyltetrahydrofolate synthetase domain containing
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
NACA2 nascent polypeptide-associated complex alpha subunit 2
NDP Norrie disease (pseudoglioma)
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NOTCH1 notch 1
PDE12 phosphodiesterase 12
PDE8B phosphodiesterase 8B
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
POM121 POM121 transmembrane nucleoporin
PTPRS protein tyrosine phosphatase, receptor type, S
RAPSN receptor-associated protein of the synapse
RARS arginyl-tRNA synthetase
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RUNDC3B RUN domain containing 3B
S100A3 S100 calcium binding protein A3
SCD5 stearoyl-CoA desaturase 5
SCUBE3 signal peptide, CUB domain, EGF-like 3
SETD8 SET domain containing (lysine methyltransferase) 8
SMAD5 SMAD family member 5
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SNORA21 small nucleolar RNA, H/ACA box 21
STAG3 stromal antigen 3
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TBC1D8B TBC1 domain family, member 8B (with GRAM domain)
TMC5 transmembrane channel-like 5
UBQLN4 ubiquilin 4
VASH2 vasohibin 2
YY2 YY2 transcription factor
ZBTB6 zinc finger and BTB domain containing 6
ZNF286A zinc finger protein 286A
ZNF37BP zinc finger protein 37B, pseudogene
ZNF654 zinc finger protein 654
ZNF675 zinc finger protein 675