fluphenazine-1017 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the fluphenazine-1017 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACVR1B activin A receptor, type IB
ADAP1 ArfGAP with dual PH domains 1
ALOX15 arachidonate 15-lipoxygenase
ANK2 ankyrin 2, neuronal
ARID4B AT rich interactive domain 4B (RBP1-like)
ARTN artemin
ATF3 activating transcription factor 3
BBS9 Bardet-Biedl syndrome 9
BHLHE40 basic helix-loop-helix family, member e40
BIRC3 baculoviral IAP repeat containing 3
C16ORF45 chromosome 16 open reading frame 45
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CD44 CD44 molecule (Indian blood group)
CDK12 cyclin-dependent kinase 12
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CXCR4 chemokine (C-X-C motif) receptor 4
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DMXL2 Dmx-like 2
DSTYK dual serine/threonine and tyrosine protein kinase
DTNA dystrobrevin, alpha
DUSP4 dual specificity phosphatase 4
EFNB3 ephrin-B3
EGR1 early growth response 1
EMC1 ER membrane protein complex subunit 1
ETV5 ets variant 5
FLJ42627 uncharacterized LOC645644
GEM GTP binding protein overexpressed in skeletal muscle
GPC4 glypican 4
GSAP gamma-secretase activating protein
GSK3A glycogen synthase kinase 3 alpha
HIP1 huntingtin interacting protein 1
HIST1H2BJ histone cluster 1, H2bj
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2
ICA1 islet cell autoantigen 1, 69kDa
ICAM1 intercellular adhesion molecule 1
IDI2-AS1 IDI2 antisense RNA 1
IFT27 intraflagellar transport 27
INSIG1 insulin induced gene 1
IRS2 insulin receptor substrate 2
ISG20 interferon stimulated exonuclease gene 20kDa
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KDM4B lysine (K)-specific demethylase 4B
KIF13B kinesin family member 13B
KLF2 Kruppel-like factor 2
KLHL24 kelch-like family member 24
LDLR low density lipoprotein receptor
LPIN1 lipin 1
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAGOH2P mago-nashi homolog 2, pseudogene
MGC12488
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MPZL1 myelin protein zero-like 1
MZF1 myeloid zinc finger 1
NDRG1 N-myc downstream regulated 1
NKX3-2 NK3 homeobox 2
PASK PAS domain containing serine/threonine kinase
PCNX pecanex homolog (Drosophila)
PHLDA1 pleckstrin homology-like domain, family A, member 1
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PLSCR3 phospholipid scramblase 3
POMT2 protein-O-mannosyltransferase 2
PRICKLE3 prickle homolog 3 (Drosophila)
PRLR prolactin receptor
QSER1 glutamine and serine rich 1
RAD23B RAD23 homolog B (S. cerevisiae)
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
RGS10 regulator of G-protein signaling 10
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
SAT1 spermidine/spermine N1-acetyltransferase 1
SCN11A sodium channel, voltage gated, type XI alpha subunit
SFTPB surfactant protein B
SH3BP2 SH3-domain binding protein 2
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SOX9 SRY (sex determining region Y)-box 9
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
SQLE squalene epoxidase
SYBU syntabulin (syntaxin-interacting)
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TCP11L1 t-complex 11, testis-specific-like 1
TIMP3 TIMP metallopeptidase inhibitor 3
TLR2 toll-like receptor 2
TRIM2 tripartite motif containing 2
TSC22D3 TSC22 domain family, member 3
TSPYL2 TSPY-like 2
ULK1 unc-51 like autophagy activating kinase 1
UPP1 uridine phosphorylase 1
USP27X ubiquitin specific peptidase 27, X-linked
VEGFA vascular endothelial growth factor A
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae)
ZER1 zyg-11 related, cell cycle regulator
ZNF155 zinc finger protein 155
ZNF500 zinc finger protein 500
ZNF573 zinc finger protein 573
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ANP32A-IT1 ANP32A intronic transcript 1
APOD apolipoprotein D
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
C6ORF47 chromosome 6 open reading frame 47
CCDC130 coiled-coil domain containing 130
CDC25A cell division cycle 25A
CGREF1 cell growth regulator with EF-hand domain 1
CHML choroideremia-like (Rab escort protein 2)
CHST10 carbohydrate sulfotransferase 10
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
E2F1 E2F transcription factor 1
ECHDC3 enoyl CoA hydratase domain containing 3
EFCAB2 EF-hand calcium binding domain 2
EFHD2 EF-hand domain family, member D2
FAAH fatty acid amide hydrolase
FICD FIC domain containing
FOSL1 FOS-like antigen 1
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GHR growth hormone receptor
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GPR19 G protein-coupled receptor 19
GRTP1 growth hormone regulated TBC protein 1
GRWD1 glutamate-rich WD repeat containing 1
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
GTPBP3 GTP binding protein 3 (mitochondrial)
HIRA histone cell cycle regulator
HIST1H2AG histone cluster 1, H2ag
HMGB3P1 high mobility group box 3 pseudogene 1
IL15RA interleukin 15 receptor, alpha
JRKL JRK-like
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KCTD20 potassium channel tetramerization domain containing 20
KCTD7 potassium channel tetramerization domain containing 7
KIAA0556 KIAA0556
LINC00339 long intergenic non-protein coding RNA 339
LMNB1 lamin B1
LOC100287590 uncharacterized LOC100287590
LPXN leupaxin
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LRRC49 leucine rich repeat containing 49
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAGOHB mago-nashi homolog B (Drosophila)
MAP1S microtubule-associated protein 1S
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MPI mannose phosphate isomerase
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
ORC1 origin recognition complex, subunit 1
OTUD3 OTU deubiquitinase 3
OXR1 oxidation resistance 1
PAQR3 progestin and adipoQ receptor family member III
PARD6A par-6 family cell polarity regulator alpha
PEX26 peroxisomal biogenesis factor 26
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PMCH pro-melanin-concentrating hormone
PRMT7 protein arginine methyltransferase 7
PTPRU protein tyrosine phosphatase, receptor type, U
PYCRL pyrroline-5-carboxylate reductase-like
RBM14 RNA binding motif protein 14
RECQL4 RecQ protein-like 4
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RNF2 ring finger protein 2
RNMTL1 RNA methyltransferase like 1
SECISBP2 SECIS binding protein 2
SETD1A SET domain containing 1A
SIRAL2 SIR2 antiphage like 2
SLC16A6 solute carrier family 16, member 6
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SLC41A3 solute carrier family 41, member 3
SLC46A3 solute carrier family 46, member 3
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SPIDR scaffolding protein involved in DNA repair
SPINK4 serine peptidase inhibitor, Kazal type 4
SPRYD7 SPRY domain containing 7
STK16 serine/threonine kinase 16
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TGFB3 transforming growth factor, beta 3
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM177 transmembrane protein 177
TMUB2 transmembrane and ubiquitin-like domain containing 2
TPTE transmembrane phosphatase with tensin homology
TRAIP TRAF interacting protein
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TTLL1 tubulin tyrosine ligase-like family member 1
UNC119 unc-119 homolog (C. elegans)
USP18 ubiquitin specific peptidase 18
USP36 ubiquitin specific peptidase 36
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast)
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZNF324 zinc finger protein 324
ZNF611 zinc finger protein 611
ZNF665 zinc finger protein 665
ZNF813 zinc finger protein 813
ZNF816 zinc finger protein 816
ZNRD1-AS1 ZNRD1 antisense RNA 1