fluphenazine-1577 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the fluphenazine-1577 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
APOL6 apolipoprotein L, 6
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2
ATG13 autophagy related 13
ATG4B autophagy related 4B, cysteine peptidase
C1ORF95 chromosome 1 open reading frame 95
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CCDC94 coiled-coil domain containing 94
CCNT1 cyclin T1
CDK17 cyclin-dependent kinase 17
CDK19 cyclin-dependent kinase 19
CDK5 cyclin-dependent kinase 5
CLEC7A C-type lectin domain family 7, member A
CTH cystathionine gamma-lyase
CUL5 cullin 5
CYLD cylindromatosis (turban tumor syndrome)
CYTH1 cytohesin 1
DCAF15 DDB1 and CUL4 associated factor 15
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DIDO1 death inducer-obliterator 1
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
DOK3 docking protein 3
DUSP6 dual specificity phosphatase 6
ELK1 ELK1, member of ETS oncogene family
ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 (putative)
FAM149B1 family with sequence similarity 149, member B1
FAM86B1 family with sequence similarity 86, member B1
FBXL4 F-box and leucine-rich repeat protein 4
FBXO21 F-box protein 21
FCHO1 FCH domain only 1
FGL1 fibrinogen-like 1
FLII flightless I homolog (Drosophila)
GALR3 galanin receptor 3
GIMAP5 GTPase, IMAP family member 5
GNB5 guanine nucleotide binding protein (G protein), beta 5
GOSR1 golgi SNAP receptor complex member 1
GRK5 G protein-coupled receptor kinase 5
HMGA2 high mobility group AT-hook 2
HMOX2 heme oxygenase 2
IQSEC1 IQ motif and Sec7 domain 1
IVD isovaleryl-CoA dehydrogenase
KIFAP3 kinesin-associated protein 3
KIFC1 kinesin family member C1
LMAN2L lectin, mannose-binding 2-like
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
MAP4 microtubule-associated protein 4
MCM3AP minichromosome maintenance complex component 3 associated protein
MISP mitotic spindle positioning
MMP19 matrix metallopeptidase 19
MPZL1 myelin protein zero-like 1
MSH3 mutS homolog 3
MTMR3 myotubularin related protein 3
MYL10 myosin, light chain 10, regulatory
NADK NAD kinase
NEU1 sialidase 1 (lysosomal sialidase)
NIPBL Nipped-B homolog (Drosophila)
OVGP1 oviductal glycoprotein 1, 120kDa
PARG poly (ADP-ribose) glycohydrolase
PCTP phosphatidylcholine transfer protein
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PKNOX2 PBX/knotted 1 homeobox 2
PPP1R10 protein phosphatase 1, regulatory subunit 10
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PRPF6 pre-mRNA processing factor 6
PRRC1 proline-rich coiled-coil 1
RABL6 RAB, member RAS oncogene family-like 6
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RTEL1 regulator of telomere elongation helicase 1
SAG S-antigen; retina and pineal gland (arrestin)
SEC23IP SEC23 interacting protein
SERINC5 serine incorporator 5
SGSM3 small G protein signaling modulator 3
SH2D3C SH2 domain containing 3C
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5
SLITRK5 SLIT and NTRK-like family, member 5
SOD2 superoxide dismutase 2, mitochondrial
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma)
ST14 suppression of tumorigenicity 14 (colon carcinoma)
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TM2D1 TM2 domain containing 1
TM7SF2 transmembrane 7 superfamily member 2
TMEM127 transmembrane protein 127
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TRAF3IP2 TRAF3 interacting protein 2
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRAIP TRAF interacting protein
TRMT61A tRNA methyltransferase 61A
TTC31 tetratricopeptide repeat domain 31
TXNIP thioredoxin interacting protein
UBE2L3 ubiquitin-conjugating enzyme E2L 3
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
VPS33B vacuolar protein sorting 33 homolog B (yeast)
WDR48 WD repeat domain 48
WDTC1 WD and tetratricopeptide repeats 1
WWP2 WW domain containing E3 ubiquitin protein ligase 2
ZBTB22 zinc finger and BTB domain containing 22
ZNF185 zinc finger protein 185 (LIM domain)
ZNF609 zinc finger protein 609
ZSWIM8 zinc finger, SWIM-type containing 8

decreased expression

Symbol Name
ABHD3 abhydrolase domain containing 3
ABT1 activator of basal transcription 1
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
AMT aminomethyltransferase
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2
ARPC1A actin related protein 2/3 complex, subunit 1A, 41kDa
ASB13 ankyrin repeat and SOCS box containing 13
ASB6 ankyrin repeat and SOCS box containing 6
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
C11ORF73 chromosome 11 open reading frame 73
C19ORF40 chromosome 19 open reading frame 40
CASZ1 castor zinc finger 1
CCL2 chemokine (C-C motif) ligand 2
CD248 CD248 molecule, endosialin
CD2AP CD2-associated protein
CD82 CD82 molecule
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CHUK conserved helix-loop-helix ubiquitous kinase
CIR1 corepressor interacting with RBPJ, 1
CLASP1 cytoplasmic linker associated protein 1
CLTCL1 clathrin, heavy chain-like 1
CRY1 cryptochrome circadian clock 1
CST3 cystatin C
CTAGE9 CTAGE family, member 9
DEF8 differentially expressed in FDCP 8 homolog (mouse)
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DRD5 dopamine receptor D5
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
ELMO1 engulfment and cell motility 1
ERF Ets2 repressor factor
FAM172A family with sequence similarity 172, member A
FUBP3 far upstream element (FUSE) binding protein 3
G6PD glucose-6-phosphate dehydrogenase
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GCC1 GRIP and coiled-coil domain containing 1
GPKOW G patch domain and KOW motifs
GSTA4 glutathione S-transferase alpha 4
GSTCD glutathione S-transferase, C-terminal domain containing
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial
ICE2 interactor of little elongation complex ELL subunit 2
INF2 inverted formin, FH2 and WH2 domain containing
INO80D INO80 complex subunit D
JUNB jun B proto-oncogene
KCTD15 potassium channel tetramerization domain containing 15
L2HGDH L-2-hydroxyglutarate dehydrogenase
LSP1 lymphocyte-specific protein 1
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAGOHB mago-nashi homolog B (Drosophila)
MAPK12 mitogen-activated protein kinase 12
MAPKBP1 mitogen-activated protein kinase binding protein 1
MFSD12 major facilitator superfamily domain containing 12
MITF microphthalmia-associated transcription factor
MLYCD malonyl-CoA decarboxylase
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
NHLRC2 NHL repeat containing 2
NIP7 NIP7, nucleolar pre-rRNA processing protein
NOD1 nucleotide-binding oligomerization domain containing 1
NOTCH1 notch 1
NR1D2 nuclear receptor subfamily 1, group D, member 2
NXF3 nuclear RNA export factor 3
OR1D2 olfactory receptor, family 1, subfamily D, member 2
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PHF21A PHD finger protein 21A
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
PODNL1 podocan-like 1
POTEKP POTE ankyrin domain family, member K, pseudogene
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RBMS3 RNA binding motif, single stranded interacting protein 3
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RPL23AP32 ribosomal protein L23a pseudogene 32
RPRD2 regulation of nuclear pre-mRNA domain containing 2
RRP1 ribosomal RNA processing 1
SDHAF3 succinate dehydrogenase complex assembly factor 3
SETD1B SET domain containing 1B
SH2B3 SH2B adaptor protein 3
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1
SNX15 sorting nexin 15
SSSCA1 Sjogren syndrome/scleroderma autoantigen 1
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STAU2 staufen double-stranded RNA binding protein 2
STK26 serine/threonine protein kinase 26
STRA13 stimulated by retinoic acid 13
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae)
SYT13 synaptotagmin XIII
TACC3 transforming, acidic coiled-coil containing protein 3
TCTN2 tectonic family member 2
TEFM transcription elongation factor, mitochondrial
TJP2 tight junction protein 2
TMEM177 transmembrane protein 177
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
WDR19 WD repeat domain 19
XDH xanthine dehydrogenase
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2