| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the fluphenazine-4461 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACE2 | angiotensin I converting enzyme 2 |
| ACTC1 | actin, alpha, cardiac muscle 1 |
| APOC4 | apolipoprotein C-IV |
| ARHGEF15 | Rho guanine nucleotide exchange factor (GEF) 15 |
| ARSA | arylsulfatase A |
| ATHL1 | ATH1, acid trehalase-like 1 (yeast) |
| BEST1 | bestrophin 1 |
| BRF1 | BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit |
| BTN3A1 | butyrophilin, subfamily 3, member A1 |
| C10ORF10 | chromosome 10 open reading frame 10 |
| C11ORF21 | chromosome 11 open reading frame 21 |
| C20ORF195 | chromosome 20 open reading frame 195 |
| CA6 | carbonic anhydrase VI |
| CACFD1 | calcium channel flower domain containing 1 |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CBS | cystathionine-beta-synthase |
| CDC25C | cell division cycle 25C |
| CDK5R2 | cyclin-dependent kinase 5, regulatory subunit 2 (p39) |
| CFAP70 | cilia and flagella associated protein 70 |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase |
| CNPY4 | canopy FGF signaling regulator 4 |
| CSHL1 | chorionic somatomammotropin hormone-like 1 |
| DCTN1 | dynactin 1 |
| DNAJB5 | DnaJ (Hsp40) homolog, subfamily B, member 5 |
| DTNA | dystrobrevin, alpha |
| EDRF1 | erythroid differentiation regulatory factor 1 |
| ENOX2 | ecto-NOX disulfide-thiol exchanger 2 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 |
| EXOSC1 | exosome component 1 |
| FAM149B1 | family with sequence similarity 149, member B1 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FOXD2 | forkhead box D2 |
| FOXG1 | forkhead box G1 |
| FOXO4 | forkhead box O4 |
| HFE | hemochromatosis |
| HPN | hepsin |
| IL6 | interleukin 6 |
| KLHL24 | kelch-like family member 24 |
| KLK12 | kallikrein-related peptidase 12 |
| KRT17 | keratin 17, type I |
| LIMD1 | LIM domains containing 1 |
| LINC01587 | long intergenic non-protein coding RNA 1587 |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LPL | lipoprotein lipase |
| LRRN2 | leucine rich repeat neuronal 2 |
| MAP2K7 | mitogen-activated protein kinase kinase 7 |
| MLLT4 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 |
| MYCNOS | MYCN opposite strand |
| NACAD | NAC alpha domain containing |
| NDUFA2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| NXF2 | nuclear RNA export factor 2 |
| OBSCN | obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF |
| OVOL1 | ovo-like zinc finger 1 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 |
| PLK3 | polo-like kinase 3 |
| PODNL1 | podocan-like 1 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PRY | PTPN13-like, Y-linked |
| PTCRA | pre T-cell antigen receptor alpha |
| PTGIS | prostaglandin I2 (prostacyclin) synthase |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| RABEP2 | rabaptin, RAB GTPase binding effector protein 2 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RBM34 | RNA binding motif protein 34 |
| RND1 | Rho family GTPase 1 |
| RORC | RAR-related orphan receptor C |
| RPL7 | ribosomal protein L7 |
| S100A5 | S100 calcium binding protein A5 |
| SAMD4B | sterile alpha motif domain containing 4B |
| SASH3 | SAM and SH3 domain containing 3 |
| SCN11A | sodium channel, voltage gated, type XI alpha subunit |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
| SH3BP1 | SH3-domain binding protein 1 |
| SH3PXD2A | SH3 and PX domains 2A |
| SLC17A7 | solute carrier family 17 (vesicular glutamate transporter), member 7 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SMAD1 | SMAD family member 1 |
| ST7L | suppression of tumorigenicity 7 like |
| TEF | thyrotrophic embryonic factor |
| TEX13A | testis expressed 13A |
| TMPRSS11D | transmembrane protease, serine 11D |
| TMPRSS2 | transmembrane protease, serine 2 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TPP1 | tripeptidyl peptidase I |
| TRIM48 | tripartite motif containing 48 |
| UGT2B15 | UDP glucuronosyltransferase 2 family, polypeptide B15 |
| VWA5A | von Willebrand factor A domain containing 5A |
| WIZ | widely interspaced zinc finger motifs |
| WNT3 | wingless-type MMTV integration site family, member 3 |
| ZC3H13 | zinc finger CCCH-type containing 13 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 |
| Symbol | Name |
|---|---|
| ADCY6 | adenylate cyclase 6 |
| AGMAT | agmatine ureohydrolase (agmatinase) |
| ALDH1B1 | aldehyde dehydrogenase 1 family, member B1 |
| ANAPC2 | anaphase promoting complex subunit 2 |
| ANKH | ANKH inorganic pyrophosphate transport regulator |
| AOC2 | amine oxidase, copper containing 2 (retina-specific) |
| APLP1 | amyloid beta (A4) precursor-like protein 1 |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ASCC2 | activating signal cointegrator 1 complex subunit 2 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BTBD2 | BTB (POZ) domain containing 2 |
| C12ORF43 | chromosome 12 open reading frame 43 |
| C1S | complement component 1, s subcomponent |
| CCDC85C | coiled-coil domain containing 85C |
| CCDC86 | coiled-coil domain containing 86 |
| CES3 | carboxylesterase 3 |
| CHMP1A | charged multivesicular body protein 1A |
| CIDEB | cell death-inducing DFFA-like effector b |
| CISH | cytokine inducible SH2-containing protein |
| CNGA1 | cyclic nucleotide gated channel alpha 1 |
| CSF1R | colony stimulating factor 1 receptor |
| CYP27B1 | cytochrome P450, family 27, subfamily B, polypeptide 1 |
| DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 |
| DDX51 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 |
| DEAF1 | DEAF1 transcription factor |
| DOCK1 | dedicator of cytokinesis 1 |
| EPN3 | epsin 3 |
| FAM131B | family with sequence similarity 131, member B |
| FBXO31 | F-box protein 31 |
| GDAP1 | ganglioside induced differentiation associated protein 1 |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 |
| GRAMD4 | GRAM domain containing 4 |
| H1F0 | H1 histone family, member 0 |
| HDAC7 | histone deacetylase 7 |
| IFI44L | interferon-induced protein 44-like |
| IL12A | interleukin 12A |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| KIAA1549L | KIAA1549-like |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LMCD1 | LIM and cysteine-rich domains 1 |
| LOC390998 | ribosomal protein L10 pseudogene |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| LRRC6 | leucine rich repeat containing 6 |
| MBD5 | methyl-CpG binding domain protein 5 |
| MCM10 | minichromosome maintenance complex component 10 |
| MDFI | MyoD family inhibitor |
| MOGS | mannosyl-oligosaccharide glucosidase |
| MTA2 | metastasis associated 1 family, member 2 |
| MXRA8 | matrix-remodelling associated 8 |
| NCALD | neurocalcin delta |
| NEUROD4 | neuronal differentiation 4 |
| NID2 | nidogen 2 (osteonidogen) |
| NPR3 | natriuretic peptide receptor 3 |
| NRTN | neurturin |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 |
| PAQR4 | progestin and adipoQ receptor family member IV |
| PAX9 | paired box 9 |
| PC | pyruvate carboxylase |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 |
| PHF14 | PHD finger protein 14 |
| PKN1 | protein kinase N1 |
| PLA1A | phospholipase A1 member A |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PTK7 | protein tyrosine kinase 7 (inactive) |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RNF216 | ring finger protein 216 |
| RPA4 | replication protein A4, 30kDa |
| RPRM | reprimo, TP53 dependent G2 arrest mediator candidate |
| SCIN | scinderin |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 |
| SLC25A15 | solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 |
| SLC46A3 | solute carrier family 46, member 3 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SLITRK5 | SLIT and NTRK-like family, member 5 |
| SMO | smoothened, frizzled class receptor |
| SMYD5 | SMYD family member 5 |
| STIM1 | stromal interaction molecule 1 |
| TMEM206 | transmembrane protein 206 |
| TNFSF12 | tumor necrosis factor (ligand) superfamily, member 12 |
| TRAIP | TRAF interacting protein |
| TRPM2 | transient receptor potential cation channel, subfamily M, member 2 |
| TUBA3C | tubulin, alpha 3c |
| TUBA3D | tubulin, alpha 3d |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| USP18 | ubiquitin specific peptidase 18 |
| USP21 | ubiquitin specific peptidase 21 |
| WDR3 | WD repeat domain 3 |
| WNT16 | wingless-type MMTV integration site family, member 16 |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| YY2 | YY2 transcription factor |
| ZNF141 | zinc finger protein 141 |
| ZNF180 | zinc finger protein 180 |
| ZNF276 | zinc finger protein 276 |
| ZNF702P | zinc finger protein 702, pseudogene |
