fluphenazine-5880 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the fluphenazine-5880 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAMDC adipogenesis associated, Mth938 domain containing
AKAP13 A kinase (PRKA) anchor protein 13
AKAP8L A kinase (PRKA) anchor protein 8-like
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
ARHGAP26 Rho GTPase activating protein 26
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
AVL9 AVL9 homolog (S. cerevisiase)
AVPR1A arginine vasopressin receptor 1A
BTN3A3 butyrophilin, subfamily 3, member A3
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CCDC85C coiled-coil domain containing 85C
CCNG2 cyclin G2
CCNO cyclin O
CCPG1 cell cycle progression 1
CD70 CD70 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CLCN7 chloride channel, voltage-sensitive 7
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CNPPD1 cyclin Pas1/PHO80 domain containing 1
COBL cordon-bleu WH2 repeat protein
CTNS cystinosin, lysosomal cystine transporter
DAPK3 death-associated protein kinase 3
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DENND3 DENN/MADD domain containing 3
DENND4A DENN/MADD domain containing 4A
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DNAL4 dynein, axonemal, light chain 4
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
ELAC2 elaC ribonuclease Z 2
ELMO3 engulfment and cell motility 3
EML2 echinoderm microtubule associated protein like 2
F7 coagulation factor VII (serum prothrombin conversion accelerator)
FAM214B family with sequence similarity 214, member B
FICD FIC domain containing
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GLS2 glutaminase 2 (liver, mitochondrial)
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
ICA1 islet cell autoantigen 1, 69kDa
IL6 interleukin 6
INSIG1 insulin induced gene 1
KDM4B lysine (K)-specific demethylase 4B
KLHL24 kelch-like family member 24
KRT34 keratin 34, type I
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LIPG lipase, endothelial
LMNB1 lamin B1
MASP2 mannan-binding lectin serine peptidase 2
MBNL3 muscleblind-like splicing regulator 3
MMP1 matrix metallopeptidase 1
MXD3 MAX dimerization protein 3
N4BP2L1 NEDD4 binding protein 2-like 1
NDRG1 N-myc downstream regulated 1
NEBL nebulette
NEK11 NIMA-related kinase 11
NEURL1 neuralized E3 ubiquitin protein ligase 1
NUPR1 nuclear protein, transcriptional regulator, 1
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
PCDH11X protocadherin 11 X-linked
PCDH11Y protocadherin 11 Y-linked
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLCD1 phospholipase C, delta 1
PLIN2 perilipin 2
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PRICKLE3 prickle homolog 3 (Drosophila)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPRH protein tyrosine phosphatase, receptor type, H
PWAR5 Prader Willi/Angelman region RNA 5
RAD23B RAD23 homolog B (S. cerevisiae)
RAD54B RAD54 homolog B (S. cerevisiae)
RARG retinoic acid receptor, gamma
RTN2 reticulon 2
RUNX1 runt-related transcription factor 1
SH2D3A SH2 domain containing 3A
SHOX2 short stature homeobox 2
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC35A2 solute carrier family 35 (UDP-galactose transporter), member A2
SLCO1A2 solute carrier organic anion transporter family, member 1A2
SNX1 sorting nexin 1
SQSTM1 sequestosome 1
SSBP2 single-stranded DNA binding protein 2
STAC SH3 and cysteine rich domain
STX7 syntaxin 7
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TBC1D30 TBC1 domain family, member 30
TCF3 transcription factor 3
TEX40 testis expressed 40
TJAP1 tight junction associated protein 1 (peripheral)
TRIB3 tribbles pseudokinase 3
TSPAN32 tetraspanin 32
TTC12 tetratricopeptide repeat domain 12
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
ULBP2 UL16 binding protein 2
WNT7A wingless-type MMTV integration site family, member 7A
ZNF407 zinc finger protein 407

decreased expression

Symbol Name
ACOX2 acyl-CoA oxidase 2, branched chain
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ARSJ arylsulfatase family, member J
ASB13 ankyrin repeat and SOCS box containing 13
AUH AU RNA binding protein/enoyl-CoA hydratase
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BRIX1 BRX1, biogenesis of ribosomes
C11ORF68 chromosome 11 open reading frame 68
C16ORF59 chromosome 16 open reading frame 59
C17ORF70 chromosome 17 open reading frame 70
C19ORF40 chromosome 19 open reading frame 40
C1ORF159 chromosome 1 open reading frame 159
C4ORF29 chromosome 4 open reading frame 29
C7ORF43 chromosome 7 open reading frame 43
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CDH3 cadherin 3, type 1, P-cadherin (placental)
CDH7 cadherin 7, type 2
CDK3 cyclin-dependent kinase 3
CNTNAP3B contactin associated protein-like 3B
CPED1 cadherin-like and PC-esterase domain containing 1
CRYBA2 crystallin, beta A2
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DCAF13 DDB1 and CUL4 associated factor 13
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DEAF1 DEAF1 transcription factor
DLEU2 deleted in lymphocytic leukemia 2 (non-protein coding)
DNAJC22 DnaJ (Hsp40) homolog, subfamily C, member 22
ECM1 extracellular matrix protein 1
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EFNA3 ephrin-A3
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
FAM50B family with sequence similarity 50, member B
FGF13 fibroblast growth factor 13
FHOD1 formin homology 2 domain containing 1
FLRT3 fibronectin leucine rich transmembrane protein 3
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GLCE glucuronic acid epimerase
GPR3 G protein-coupled receptor 3
GRWD1 glutamate-rich WD repeat containing 1
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene)
HAMP hepcidin antimicrobial peptide
HIRIP3 HIRA interacting protein 3
HIST1H1E histone cluster 1, H1e
HIST1H2AG histone cluster 1, H2ag
HIST1H2BI histone cluster 1, H2bi
HMHA1 histocompatibility (minor) HA-1
KIAA0894 KIAA0894 protein
KIAA1549L KIAA1549-like
KIF13B kinesin family member 13B
LIMS2 LIM and senescent cell antigen-like domains 2
LYPD1 LY6/PLAUR domain containing 1
MAGEH1 melanoma antigen family H1
MAPK12 mitogen-activated protein kinase 12
MCM3AP-AS1 MCM3AP antisense RNA 1
MCRS1 microspherule protein 1
METRN meteorin, glial cell differentiation regulator
NAG18 NAG18 mRNA
NCS1 neuronal calcium sensor 1
NDE1 nudE neurodevelopment protein 1
NDP Norrie disease (pseudoglioma)
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PALMD palmdelphin
PHC1 polyhomeotic homolog 1 (Drosophila)
POLD1 polymerase (DNA directed), delta 1, catalytic subunit
PRMT7 protein arginine methyltransferase 7
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
RAB3A RAB3A, member RAS oncogene family
RAD54L2 RAD54-like 2 (S. cerevisiae)
RNF126P1 ring finger protein 126 pseudogene 1
RNF31 ring finger protein 31
RPAP1 RNA polymerase II associated protein 1
RPL10L ribosomal protein L10-like
RPL23AP32 ribosomal protein L23a pseudogene 32
S100A4 S100 calcium binding protein A4
SCAMP5 secretory carrier membrane protein 5
SCN1B sodium channel, voltage gated, type I beta subunit
SIDT1 SID1 transmembrane family, member 1
SIRT2 sirtuin 2
SNHG3 small nucleolar RNA host gene 3
STAG3L4 stromal antigen 3-like 4 (pseudogene)
TAOK1 TAO kinase 1
TCTN1 tectonic family member 1
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TOR3A torsin family 3, member A
TOR4A torsin family 4, member A
TRAIP TRAF interacting protein
TRDMT1 tRNA aspartic acid methyltransferase 1
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TUBA3C tubulin, alpha 3c
UROS uroporphyrinogen III synthase
ZC3H12A zinc finger CCCH-type containing 12A
ZMYM1 zinc finger, MYM-type 1
ZNF107 zinc finger protein 107
ZNF276 zinc finger protein 276
ZNF350 zinc finger protein 350
ZNF426 zinc finger protein 426
ZNF85 zinc finger protein 85