fluphenazine-6196 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the fluphenazine-6196 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABI2 abl-interactor 2
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ACSS3 acyl-CoA synthetase short-chain family member 3
ADAM5 ADAM metallopeptidase domain 5 (pseudogene)
ADCK2 aarF domain containing kinase 2
ADCY9 adenylate cyclase 9
APAF1 apoptotic peptidase activating factor 1
ATP13A2 ATPase type 13A2
BIN1 bridging integrator 1
C7ORF69 chromosome 7 open reading frame 69
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CASP5 caspase 5, apoptosis-related cysteine peptidase
CD180 CD180 molecule
CD34 CD34 molecule
CD36 CD36 molecule (thrombospondin receptor)
CDHR2 cadherin-related family member 2
CDRT1 CMT1A duplicated region transcript 1
CLTA clathrin, light chain A
COL1A1 collagen, type I, alpha 1
COL4A2 collagen, type IV, alpha 2
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CXCL10 chemokine (C-X-C motif) ligand 10
DCAF17 DDB1 and CUL4 associated factor 17
DIAPH2 diaphanous-related formin 2
DVL2 dishevelled segment polarity protein 2
ELL elongation factor RNA polymerase II
FAS Fas cell surface death receptor
FGF6 fibroblast growth factor 6
FST follistatin
GABARAPL3 GABA(A) receptors associated protein like 3, pseudogene
GHRHR growth hormone releasing hormone receptor
GIMAP4 GTPase, IMAP family member 4
GNG12 guanine nucleotide binding protein (G protein), gamma 12
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
GPR107 G protein-coupled receptor 107
GPR161 G protein-coupled receptor 161
GPR68 G protein-coupled receptor 68
GPX2 glutathione peroxidase 2
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GYPB glycophorin B (MNS blood group)
IL16 interleukin 16
KIDINS220 kinase D-interacting substrate, 220kDa
KLHL3 kelch-like family member 3
KLHL36 kelch-like family member 36
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
MR1 major histocompatibility complex, class I-related
MRC2 mannose receptor, C type 2
MROH7 maestro heat-like repeat family member 7
MUC3A mucin 3A, cell surface associated
MYH6 myosin, heavy chain 6, cardiac muscle, alpha
MYO1B myosin IB
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
NAG18 NAG18 mRNA
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
NPEPL1 aminopeptidase-like 1
NUP188 nucleoporin 188kDa
OSBPL7 oxysterol binding protein-like 7
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCDHA5 protocadherin alpha 5
PCDHGC3 protocadherin gamma subfamily C, 3
PCLO piccolo presynaptic cytomatrix protein
PDE4DIP phosphodiesterase 4D interacting protein
PHLDA3 pleckstrin homology-like domain, family A, member 3
PIAS2 protein inhibitor of activated STAT, 2
PLAC1 placenta-specific 1
PLCH1 phospholipase C, eta 1
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PRDM2 PR domain containing 2, with ZNF domain
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKD1 protein kinase D1
PRPH peripherin
PTCRA pre T-cell antigen receptor alpha
RTEL1 regulator of telomere elongation helicase 1
RUNX1 runt-related transcription factor 1
SHB Src homology 2 domain containing adaptor protein B
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SIT1 signaling threshold regulating transmembrane adaptor 1
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
SMTN smoothelin
SORBS3 sorbin and SH3 domain containing 3
SP1 Sp1 transcription factor
ST7L suppression of tumorigenicity 7 like
STOML1 stomatin (EPB72)-like 1
SULT4A1 sulfotransferase family 4A, member 1
TEF thyrotrophic embryonic factor
TLR6 toll-like receptor 6
TNK1 tyrosine kinase, non-receptor, 1
TOP3A topoisomerase (DNA) III alpha
TRIM23 tripartite motif containing 23
TRIO trio Rho guanine nucleotide exchange factor
VASH1 vasohibin 1
VSNL1 visinin-like 1
WAPAL wings apart-like homolog (Drosophila)
ZIC3 Zic family member 3

decreased expression

Symbol Name
ADAMDEC1 ADAM-like, decysin 1
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ANKH ANKH inorganic pyrophosphate transport regulator
ARHGAP12 Rho GTPase activating protein 12
BCAS3 breast carcinoma amplified sequence 3
BMP15 bone morphogenetic protein 15
C1ORF159 chromosome 1 open reading frame 159
C1RL complement component 1, r subcomponent-like
C22ORF29 chromosome 22 open reading frame 29
CDR2L cerebellar degeneration-related protein 2-like
CGREF1 cell growth regulator with EF-hand domain 1
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CRELD1 cysteine-rich with EGF-like domains 1
CRY2 cryptochrome circadian clock 2
CXORF56 chromosome X open reading frame 56
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DDN dendrin
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DOCK4 dedicator of cytokinesis 4
DPY19L2P2 DPY19L2 pseudogene 2
ECM1 extracellular matrix protein 1
EFNA4 ephrin-A4
ERAP2 endoplasmic reticulum aminopeptidase 2
FAM131A family with sequence similarity 131, member A
FAM204A family with sequence similarity 204, member A
FAM86C1 family with sequence similarity 86, member C1
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FCHO1 FCH domain only 1
FKBP9 FK506 binding protein 9, 63 kDa
FRMD1 FERM domain containing 1
FSTL3 follistatin-like 3 (secreted glycoprotein)
GAA glucosidase, alpha; acid
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GPR35 G protein-coupled receptor 35
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HIST1H2AJ histone cluster 1, H2aj
HOXA1 homeobox A1
IFI44L interferon-induced protein 44-like
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
INA internexin neuronal intermediate filament protein, alpha
IRAK4 interleukin-1 receptor-associated kinase 4
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KIAA0319L KIAA0319-like
KIAA1024 KIAA1024
KLK5 kallikrein-related peptidase 5
LIN7A lin-7 homolog A (C. elegans)
LINC00597 long intergenic non-protein coding RNA 597
LZTR1 leucine-zipper-like transcription regulator 1
MAGEF1 melanoma antigen family F1
MBNL3 muscleblind-like splicing regulator 3
METRN meteorin, glial cell differentiation regulator
METTL2B methyltransferase like 2B
MTA2 metastasis associated 1 family, member 2
NABP1 nucleic acid binding protein 1
NCALD neurocalcin delta
NSUN6 NOP2/Sun domain family, member 6
OLAH oleoyl-ACP hydrolase
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OVGP1 oviductal glycoprotein 1, 120kDa
PARP16 poly (ADP-ribose) polymerase family, member 16
PENK proenkephalin
PFN2 profilin 2
PID1 phosphotyrosine interaction domain containing 1
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PQLC2 PQ loop repeat containing 2
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRSS12 protease, serine, 12 (neurotrypsin, motopsin)
PTPRS protein tyrosine phosphatase, receptor type, S
R3HCC1L R3H domain and coiled-coil containing 1-like
RBM38 RNA binding motif protein 38
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
SCUBE3 signal peptide, CUB domain, EGF-like 3
SETD1A SET domain containing 1A
SLC16A6 solute carrier family 16, member 6
SLMO1 slowmo homolog 1 (Drosophila)
SNX16 sorting nexin 16
SPAG1 sperm associated antigen 1
STBD1 starch binding domain 1
STK25 serine/threonine kinase 25
STX1A syntaxin 1A (brain)
TBC1D17 TBC1 domain family, member 17
TET3 tet methylcytosine dioxygenase 3
TGFBR3 transforming growth factor, beta receptor III
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TMEM209 transmembrane protein 209
TMEM246 transmembrane protein 246
TMEM254 transmembrane protein 254
TNNT1 troponin T type 1 (skeletal, slow)
TRAF1 TNF receptor-associated factor 1
TSPAN13 tetraspanin 13
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
WDR25 WD repeat domain 25
ZC3H12A zinc finger CCCH-type containing 12A
ZDHHC14 zinc finger, DHHC-type containing 14
ZNRD1-AS1 ZNRD1 antisense RNA 1