fluphenazine-6996 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the fluphenazine-6996 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
AKAP9 A kinase (PRKA) anchor protein 9
ANKMY1 ankyrin repeat and MYND domain containing 1
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2
ANKRD12 ankyrin repeat domain 12
ANXA2P3 annexin A2 pseudogene 3
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2
ATF3 activating transcription factor 3
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
ATXN1 ataxin 1
AURKA aurora kinase A
BAHCC1 BAH domain and coiled-coil containing 1
C19ORF73 chromosome 19 open reading frame 73
CA5BP1 carbonic anhydrase VB pseudogene 1
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CCDC93 coiled-coil domain containing 93
CCNG2 cyclin G2
CCR7 chemokine (C-C motif) receptor 7
CD59 CD59 molecule, complement regulatory protein
CFAP44 cilia and flagella associated protein 44
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
COL5A1 collagen, type V, alpha 1
CTH cystathionine gamma-lyase
CTNS cystinosin, lysosomal cystine transporter
CXCR4 chemokine (C-X-C motif) receptor 4
CYLD cylindromatosis (turban tumor syndrome)
DUSP4 dual specificity phosphatase 4
EGR1 early growth response 1
EMC1 ER membrane protein complex subunit 1
EMID1 EMI domain containing 1
EPHA1 EPH receptor A1
EPN2 epsin 2
ERN2 endoplasmic reticulum to nucleus signaling 2
F3 coagulation factor III (thromboplastin, tissue factor)
FADS3 fatty acid desaturase 3
FGFR2 fibroblast growth factor receptor 2
GPR87 G protein-coupled receptor 87
HEXA hexosaminidase A (alpha polypeptide)
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IFNAR1 interferon (alpha, beta and omega) receptor 1
IFT27 intraflagellar transport 27
IL27RA interleukin 27 receptor, alpha
IL4R interleukin 4 receptor
INSIG1 insulin induced gene 1
IRF2BP1 interferon regulatory factor 2 binding protein 1
IRF6 interferon regulatory factor 6
ISG20 interferon stimulated exonuclease gene 20kDa
JUN jun proto-oncogene
KLHL24 kelch-like family member 24
KRIT1 KRIT1, ankyrin repeat containing
KRT19P2 keratin 19 pseudogene 2
LDLR low density lipoprotein receptor
LIG3 ligase III, DNA, ATP-dependent
LPIN1 lipin 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MAST4 microtubule associated serine/threonine kinase family member 4
MED12 mediator complex subunit 12
MVD mevalonate (diphospho) decarboxylase
NAV2 neuron navigator 2
NDRG1 N-myc downstream regulated 1
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NKX3-2 NK3 homeobox 2
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
PAQR6 progestin and adipoQ receptor family member VI
PCDHA6 protocadherin alpha 6
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLCD1 phospholipase C, delta 1
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PTGES prostaglandin E synthase
RAB27B RAB27B, member RAS oncogene family
RAB30 RAB30, member RAS oncogene family
RABEP2 rabaptin, RAB GTPase binding effector protein 2
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
RRAGB Ras-related GTP binding B
RUNX1 runt-related transcription factor 1
SAT1 spermidine/spermine N1-acetyltransferase 1
SETD8 SET domain containing (lysine methyltransferase) 8
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SH3BP2 SH3-domain binding protein 2
SIDT2 SID1 transmembrane family, member 2
SIGLEC15 sialic acid binding Ig-like lectin 15
SIK1 salt-inducible kinase 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SQSTM1 sequestosome 1
SRCAP Snf2-related CREBBP activator protein
SREBF2 sterol regulatory element binding transcription factor 2
SYBU syntabulin (syntaxin-interacting)
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TBCD tubulin folding cofactor D
TK2 thymidine kinase 2, mitochondrial
TRIM2 tripartite motif containing 2
TTLL1 tubulin tyrosine ligase-like family member 1
TULP3 tubby like protein 3
WDR19 WD repeat domain 19
ZMYND8 zinc finger, MYND-type containing 8
ZNF606 zinc finger protein 606
ZNF609 zinc finger protein 609

decreased expression

Symbol Name
ACADSB acyl-CoA dehydrogenase, short/branched chain
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARHGAP10 Rho GTPase activating protein 10
ARMC6 armadillo repeat containing 6
ASB7 ankyrin repeat and SOCS box containing 7
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ATAD5 ATPase family, AAA domain containing 5
ATF7IP2 activating transcription factor 7 interacting protein 2
AXIN1 axin 1
BACE1 beta-site APP-cleaving enzyme 1
BFSP1 beaded filament structural protein 1, filensin
BHLHB9 basic helix-loop-helix domain containing, class B, 9
C10ORF95 chromosome 10 open reading frame 95
C5 complement component 5
C9ORF40 chromosome 9 open reading frame 40
CALCOCO1 calcium binding and coiled-coil domain 1
CAPRIN2 caprin family member 2
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CLCN2 chloride channel, voltage-sensitive 2
CLCN5 chloride channel, voltage-sensitive 5
COPS7B COP9 signalosome subunit 7B
CPPED1 calcineurin-like phosphoesterase domain containing 1
CRYGC crystallin, gamma C
CTAGE9 CTAGE family, member 9
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DNAL4 dynein, axonemal, light chain 4
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
ECHDC3 enoyl CoA hydratase domain containing 3
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
EPHA2 EPH receptor A2
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FAAH fatty acid amide hydrolase
FAM222B family with sequence similarity 222, member B
FGGY FGGY carbohydrate kinase domain containing
GALK1 galactokinase 1
GAN gigaxonin
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPATCH3 G patch domain containing 3
GRWD1 glutamate-rich WD repeat containing 1
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HHLA3 HERV-H LTR-associating 3
HIRA histone cell cycle regulator
HPS6 Hermansky-Pudlak syndrome 6
INF2 inverted formin, FH2 and WH2 domain containing
JMJD4 jumonji domain containing 4
KIFC1 kinesin family member C1
KLF2 Kruppel-like factor 2
KLHL26 kelch-like family member 26
KREMEN2 kringle containing transmembrane protein 2
KRI1 KRI1 homolog (S. cerevisiae)
LAMA5 laminin, alpha 5
LIN7B lin-7 homolog B (C. elegans)
LMBR1L limb development membrane protein 1-like
LY6D lymphocyte antigen 6 complex, locus D
LYRM9 LYR motif containing 9
LZTR1 leucine-zipper-like transcription regulator 1
MAP9 microtubule-associated protein 9
MGC12488
MITF microphthalmia-associated transcription factor
MRPL52 mitochondrial ribosomal protein L52
MXD3 MAX dimerization protein 3
NPY5R neuropeptide Y receptor Y5
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PDK2 pyruvate dehydrogenase kinase, isozyme 2
PIGH phosphatidylinositol glycan anchor biosynthesis, class H
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLD3 phospholipase D family, member 3
RAB3A RAB3A, member RAS oncogene family
REM1 RAS (RAD and GEM)-like GTP-binding 1
REPS2 RALBP1 associated Eps domain containing 2
ROM1 retinal outer segment membrane protein 1
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SFT2D2 SFT2 domain containing 2
SH2D4A SH2 domain containing 4A
SLC12A8 solute carrier family 12, member 8
SLMO1 slowmo homolog 1 (Drosophila)
THAP4 THAP domain containing 4
TMC7 transmembrane channel-like 7
TMEM104 transmembrane protein 104
TSPYL2 TSPY-like 2
UBQLN4 ubiquilin 4
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
URM1 ubiquitin related modifier 1
VGF VGF nerve growth factor inducible
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WDR33 WD repeat domain 33
WDR62 WD repeat domain 62
WDR76 WD repeat domain 76
WDR91 WD repeat domain 91
WRAP73 WD repeat containing, antisense to TP73
XYLT2 xylosyltransferase II
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF276 zinc finger protein 276
ZNF324 zinc finger protein 324
ZNF350 zinc finger protein 350
ZNF510 zinc finger protein 510
ZSCAN26 zinc finger and SCAN domain containing 26