flurbiprofen-3095 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the flurbiprofen-3095 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADD2 adducin 2 (beta)
ADRB3 adrenoceptor beta 3
AGTR2 angiotensin II receptor, type 2
ALDOB aldolase B, fructose-bisphosphate
B9D1 B9 protein domain 1
C11ORF16 chromosome 11 open reading frame 16
CBR3 carbonyl reductase 3
CCDC92 coiled-coil domain containing 92
CDRT1 CMT1A duplicated region transcript 1
CNGB3 cyclic nucleotide gated channel beta 3
CPE carboxypeptidase E
CREM cAMP responsive element modulator
DMP1 dentin matrix acidic phosphoprotein 1
DOK5 docking protein 5
DPEP2 dipeptidase 2
DPYS dihydropyrimidinase
EFNA4 ephrin-A4
EPB41L4A erythrocyte membrane protein band 4.1 like 4A
ERICH1 glutamate-rich 1
FBXL7 F-box and leucine-rich repeat protein 7
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GOSR2 golgi SNAP receptor complex member 2
GP1BA glycoprotein Ib (platelet), alpha polypeptide
HCG4 HLA complex group 4 (non-protein coding)
HDAC6 histone deacetylase 6
ICOSLG inducible T-cell co-stimulator ligand
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFITM1 interferon induced transmembrane protein 1
IGFBP5 insulin-like growth factor binding protein 5
IL1R1 interleukin 1 receptor, type I
IL3RA interleukin 3 receptor, alpha (low affinity)
ING2 inhibitor of growth family, member 2
ISL1 ISL LIM homeobox 1
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KHK ketohexokinase (fructokinase)
KIF26B kinesin family member 26B
KLHL25 kelch-like family member 25
KLK13 kallikrein-related peptidase 13
LPPR3 lipid phosphate phosphatase-related protein type 3
MAK male germ cell-associated kinase
MAP4 microtubule-associated protein 4
MED16 mediator complex subunit 16
MED27 mediator complex subunit 27
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
MNX1 motor neuron and pancreas homeobox 1
MRPS12 mitochondrial ribosomal protein S12
MSR1 macrophage scavenger receptor 1
MVD mevalonate (diphospho) decarboxylase
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
NEBL nebulette
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NKX3-2 NK3 homeobox 2
NPPA natriuretic peptide A
P2RY4 pyrimidinergic receptor P2Y, G-protein coupled, 4
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCLO piccolo presynaptic cytomatrix protein
PGLYRP4 peptidoglycan recognition protein 4
PLA2G3 phospholipase A2, group III
PLCE1 phospholipase C, epsilon 1
PLEKHS1 pleckstrin homology domain containing, family S member 1
PLG plasminogen
PPP1R13L protein phosphatase 1, regulatory subunit 13 like
PPP1R26 protein phosphatase 1, regulatory subunit 26
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa
PTGIS prostaglandin I2 (prostacyclin) synthase
PURG purine-rich element binding protein G
RAB6B RAB6B, member RAS oncogene family
RHO rhodopsin
RIF1 replication timing regulatory factor 1
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
SCARB2 scavenger receptor class B, member 2
SCN5A sodium channel, voltage gated, type V alpha subunit
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
SHOX2 short stature homeobox 2
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC35D2 solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2
SMAD3 SMAD family member 3
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SPRR1B small proline-rich protein 1B
SSPN sarcospan
SSTR5 somatostatin receptor 5
ST5 suppression of tumorigenicity 5
SV2A synaptic vesicle glycoprotein 2A
SYT2 synaptotagmin II
TLDC1 TBC/LysM-associated domain containing 1
TMLHE trimethyllysine hydroxylase, epsilon
TNK2 tyrosine kinase, non-receptor, 2
TPMT thiopurine S-methyltransferase
TRIM29 tripartite motif containing 29
TRIM3 tripartite motif containing 3
TSPAN9 tetraspanin 9
USP53 ubiquitin specific peptidase 53
YLPM1 YLP motif containing 1
ZIM2 zinc finger, imprinted 2
ZNF219 zinc finger protein 219
ZNF668 zinc finger protein 668

decreased expression

Symbol Name
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ANAPC2 anaphase promoting complex subunit 2
ANGEL1 angel homolog 1 (Drosophila)
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ARMC6 armadillo repeat containing 6
ASGR2 asialoglycoprotein receptor 2
ASTE1 asteroid homolog 1 (Drosophila)
BEND5 BEN domain containing 5
BTNL3 butyrophilin-like 3
C5 complement component 5
CAPN15 calpain 15
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC9 coiled-coil domain containing 9
CD320 CD320 molecule
CDK6 cyclin-dependent kinase 6
CHMP7 charged multivesicular body protein 7
CIDEC cell death-inducing DFFA-like effector c
CLEC2D C-type lectin domain family 2, member D
CLEC3B C-type lectin domain family 3, member B
CRYL1 crystallin, lambda 1
DCSTAMP dendrocyte expressed seven transmembrane protein
DEAF1 DEAF1 transcription factor
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
ELP6 elongator acetyltransferase complex subunit 6
ELSPBP1 epididymal sperm binding protein 1
ERCC2 excision repair cross-complementation group 2
FAM127B family with sequence similarity 127, member B
FAM50B family with sequence similarity 50, member B
FGF9 fibroblast growth factor 9
FGGY FGGY carbohydrate kinase domain containing
FHL3 four and a half LIM domains 3
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GPR132 G protein-coupled receptor 132
HAMP hepcidin antimicrobial peptide
HIST1H1B histone cluster 1, H1b
HIST1H4C histone cluster 1, H4c
HIST1H4D histone cluster 1, H4d
HIST2H2AA3 histone cluster 2, H2aa3
HYAL3 hyaluronoglucosaminidase 3
JAM2 junctional adhesion molecule 2
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KCTD7 potassium channel tetramerization domain containing 7
KIAA0319L KIAA0319-like
KIAA1024 KIAA1024
KIF24 kinesin family member 24
KLHL26 kelch-like family member 26
KLRAP1 killer cell lectin-like receptor subfamily A pseudogene 1
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LIN7A lin-7 homolog A (C. elegans)
MCTP2 multiple C2 domains, transmembrane 2
MLPH melanophilin
MXD3 MAX dimerization protein 3
NDE1 nudE neurodevelopment protein 1
NINJ2 ninjurin 2
NOL10 nucleolar protein 10
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PDGFD platelet derived growth factor D
PERP PERP, TP53 apoptosis effector
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLTP phospholipid transfer protein
PMFBP1 polyamine modulated factor 1 binding protein 1
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PTCD1 pentatricopeptide repeat domain 1
QTRT1 queuine tRNA-ribosyltransferase 1
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RIN1 Ras and Rab interactor 1
RPP25 ribonuclease P/MRP 25kDa subunit
RRAGB Ras-related GTP binding B
SALL2 spalt-like transcription factor 2
SCGB2A2 secretoglobin, family 2A, member 2
SIRT2 sirtuin 2
SLC12A9 solute carrier family 12, member 9
SLPI secretory leukocyte peptidase inhibitor
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SSH3 slingshot protein phosphatase 3
ST7L suppression of tumorigenicity 7 like
STEAP3 STEAP family member 3, metalloreductase
STK16 serine/threonine kinase 16
TEC tec protein tyrosine kinase
TGFBR3 transforming growth factor, beta receptor III
TIAM2 T-cell lymphoma invasion and metastasis 2
TMEM177 transmembrane protein 177
TMEM242 transmembrane protein 242
TRAF1 TNF receptor-associated factor 1
TRAIP TRAF interacting protein
TRIM36 tripartite motif containing 36
TUBG2 tubulin, gamma 2
UBQLN4 ubiquilin 4
UPK3A uroplakin 3A
USB1 U6 snRNA biogenesis 1
XYLT2 xylosyltransferase II
YOD1 YOD1 deubiquitinase
ZNF177 zinc finger protein 177
ZNF280B zinc finger protein 280B
ZNF286A zinc finger protein 286A
ZNF574 zinc finger protein 574
ZNF74 zinc finger protein 74