| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the flurbiprofen-5269 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| ADAM7 | ADAM metallopeptidase domain 7 |
| ADAMTS20 | ADAM metallopeptidase with thrombospondin type 1 motif, 20 |
| ADH7 | alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide |
| AHSP | alpha hemoglobin stabilizing protein |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| ATG10 | autophagy related 10 |
| ATN1 | atrophin 1 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| BCL2 | B-cell CLL/lymphoma 2 |
| BIRC7 | baculoviral IAP repeat containing 7 |
| BMP1 | bone morphogenetic protein 1 |
| CA1 | carbonic anhydrase I |
| CALCR | calcitonin receptor |
| CD4 | CD4 molecule |
| CD52 | CD52 molecule |
| CD53 | CD53 molecule |
| CEP41 | centrosomal protein 41kDa |
| CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
| COL13A1 | collagen, type XIII, alpha 1 |
| CSF1 | colony stimulating factor 1 (macrophage) |
| CSN3 | casein kappa |
| CTSF | cathepsin F |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CYP27A1 | cytochrome P450, family 27, subfamily A, polypeptide 1 |
| DGCR2 | DiGeorge syndrome critical region gene 2 |
| DIO2 | deiodinase, iodothyronine, type II |
| DMXL2 | Dmx-like 2 |
| EGR3 | early growth response 3 |
| EPX | eosinophil peroxidase |
| EVI2B | ecotropic viral integration site 2B |
| FAM131A | family with sequence similarity 131, member A |
| FBLN1 | fibulin 1 |
| FOSL2 | FOS-like antigen 2 |
| FUT3 | fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) |
| GPR137 | G protein-coupled receptor 137 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| IGFBP3 | insulin-like growth factor binding protein 3 |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| INHBA | inhibin, beta A |
| INO80D | INO80 complex subunit D |
| INPP5J | inositol polyphosphate-5-phosphatase J |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| ITGB6 | integrin, beta 6 |
| IZUMO4 | IZUMO family member 4 |
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog |
| KLRD1 | killer cell lectin-like receptor subfamily D, member 1 |
| KRT19P2 | keratin 19 pseudogene 2 |
| LIF | leukemia inhibitory factor |
| LINC00341 | long intergenic non-protein coding RNA 341 |
| MAPK14 | mitogen-activated protein kinase 14 |
| MAPK7 | mitogen-activated protein kinase 7 |
| MED27 | mediator complex subunit 27 |
| MGC2889 | uncharacterized protein MGC2889 |
| MIER2 | mesoderm induction early response 1, family member 2 |
| MINK1 | misshapen-like kinase 1 |
| MTMR3 | myotubularin related protein 3 |
| NDUFAF5 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 5 |
| NPY | neuropeptide Y |
| NR2E3 | nuclear receptor subfamily 2, group E, member 3 |
| OR2H2 | olfactory receptor, family 2, subfamily H, member 2 |
| OXCT2 | 3-oxoacid CoA transferase 2 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited |
| PDGFD | platelet derived growth factor D |
| PHLDB1 | pleckstrin homology-like domain, family B, member 1 |
| PI4K2A | phosphatidylinositol 4-kinase type 2 alpha |
| PKNOX2 | PBX/knotted 1 homeobox 2 |
| PLAT | plasminogen activator, tissue |
| PLEKHG3 | pleckstrin homology domain containing, family G (with RhoGef domain) member 3 |
| PML | promyelocytic leukemia |
| PRR34 | proline rich 34 |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| PURA | purine-rich element binding protein A |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) |
| RXRB | retinoid X receptor, beta |
| SDC3 | syndecan 3 |
| SEC14L2 | SEC14-like 2 (S. cerevisiae) |
| SETD1B | SET domain containing 1B |
| SGCD | sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) |
| SIRT5 | sirtuin 5 |
| SLC24A1 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 |
| TBKBP1 | TBK1 binding protein 1 |
| TEF | thyrotrophic embryonic factor |
| TEX13B | testis expressed 13B |
| TMOD2 | tropomodulin 2 (neuronal) |
| TPSG1 | tryptase gamma 1 |
| TUBA4B | tubulin, alpha 4b |
| UPK3B | uroplakin 3B |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) |
| ZEB1 | zinc finger E-box binding homeobox 1 |
| ZNF493 | zinc finger protein 493 |
| ZNF639 | zinc finger protein 639 |
| ZNF76 | zinc finger protein 76 |
| ZXDB | zinc finger, X-linked, duplicated B |
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| ALPK1 | alpha-kinase 1 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ATP6V1G2 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 |
| BLNK | B-cell linker |
| CARF | calcium responsive transcription factor |
| CCDC132 | coiled-coil domain containing 132 |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CLDN1 | claudin 1 |
| CSTA | cystatin A (stefin A) |
| CXXC4 | CXXC finger protein 4 |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DNAH17 | dynein, axonemal, heavy chain 17 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DNAJC24 | DnaJ (Hsp40) homolog, subfamily C, member 24 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DVL1 | dishevelled segment polarity protein 1 |
| DYSF | dysferlin |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 |
| EPHX2 | epoxide hydrolase 2, cytoplasmic |
| ERCC6 | excision repair cross-complementation group 6 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| ETV6 | ets variant 6 |
| FGF13 | fibroblast growth factor 13 |
| FGF23 | fibroblast growth factor 23 |
| FLJ11710 | uncharacterized protein FLJ11710 |
| FLJ22184 | |
| FLT4 | fms-related tyrosine kinase 4 |
| FRMD1 | FERM domain containing 1 |
| GID4 | GID complex subunit 4 |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| GPATCH2L | G patch domain containing 2-like |
| GRB7 | growth factor receptor-bound protein 7 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HOOK1 | hook microtubule-tethering protein 1 |
| HOXC10 | homeobox C10 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFT54 | intraflagellar transport 54 |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
| KCNK12 | potassium channel, two pore domain subfamily K, member 12 |
| KIF13B | kinesin family member 13B |
| KIF5A | kinesin family member 5A |
| KLHL25 | kelch-like family member 25 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 |
| MRPL41 | mitochondrial ribosomal protein L41 |
| MUC3A | mucin 3A, cell surface associated |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| NEUROD4 | neuronal differentiation 4 |
| NLRX1 | NLR family member X1 |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| PDE12 | phosphodiesterase 12 |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PLA2G10 | phospholipase A2, group X |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PREX2 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 |
| PTGER2 | prostaglandin E receptor 2 (subtype EP2), 53kDa |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RASAL1 | RAS protein activator like 1 (GAP1 like) |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| SCAI | suppressor of cancer cell invasion |
| SLC12A5 | solute carrier family 12 (potassium/chloride transporter), member 5 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 |
| SLC46A3 | solute carrier family 46, member 3 |
| ST20 | suppressor of tumorigenicity 20 |
| STARD3 | StAR-related lipid transfer (START) domain containing 3 |
| SYNC | syncoilin, intermediate filament protein |
| TAOK1 | TAO kinase 1 |
| TARP | TCR gamma alternate reading frame protein |
| TBC1D17 | TBC1 domain family, member 17 |
| TEP1 | telomerase-associated protein 1 |
| TGFBI | transforming growth factor, beta-induced, 68kDa |
| THBS3 | thrombospondin 3 |
| TNFSF18 | tumor necrosis factor (ligand) superfamily, member 18 |
| VAX2 | ventral anterior homeobox 2 |
| VLDLR | very low density lipoprotein receptor |
| WDR33 | WD repeat domain 33 |
| WDR91 | WD repeat domain 91 |
| XYLT1 | xylosyltransferase I |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZNF219 | zinc finger protein 219 |
| ZNF430 | zinc finger protein 430 |
| ZNF480 | zinc finger protein 480 |
| ZNF652 | zinc finger protein 652 |
| ZNF8 | zinc finger protein 8 |
| ZNF862 | zinc finger protein 862 |
