flurbiprofen-5634 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the flurbiprofen-5634 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAA2 acetyl-CoA acyltransferase 2
ACBD4 acyl-CoA binding domain containing 4
AIM2 absent in melanoma 2
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit
ARG1 arginase 1
ASCL1 achaete-scute family bHLH transcription factor 1
ASIC4 acid sensing (proton gated) ion channel family member 4
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
C1ORF95 chromosome 1 open reading frame 95
CA1 carbonic anhydrase I
CASP10 caspase 10, apoptosis-related cysteine peptidase
CC2D1A coiled-coil and C2 domain containing 1A
CD22 CD22 molecule
CEL carboxyl ester lipase
CLDN14 claudin 14
CLIP3 CAP-GLY domain containing linker protein 3
CNN1 calponin 1, basic, smooth muscle
CNTLN centlein, centrosomal protein
CUX2 cut-like homeobox 2
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP2A7 cytochrome P450, family 2, subfamily A, polypeptide 7
DEPDC5 DEP domain containing 5
DFNB31 deafness, autosomal recessive 31
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16
DSCC1 DNA replication and sister chromatid cohesion 1
EDNRB endothelin receptor type B
EFNA3 ephrin-A3
EFNB3 ephrin-B3
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
F13A1 coagulation factor XIII, A1 polypeptide
FAM182B family with sequence similarity 182, member B
FAM76A family with sequence similarity 76, member A
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
FUBP1 far upstream element (FUSE) binding protein 1
GNG7 guanine nucleotide binding protein (G protein), gamma 7
HKDC1 hexokinase domain containing 1
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
ICA1 islet cell autoantigen 1, 69kDa
ICAM1 intercellular adhesion molecule 1
ICAM2 intercellular adhesion molecule 2
ICOS inducible T-cell co-stimulator
IGF1R insulin-like growth factor 1 receptor
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIR3DX1 killer cell immunoglobulin-like receptor, three domains, X1
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LAMC2 laminin, gamma 2
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LMTK1 lemur tail kinase 1
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MAPK8 mitogen-activated protein kinase 8
MLXIP MLX interacting protein
MPL MPL proto-oncogene, thrombopoietin receptor
MTOR mechanistic target of rapamycin (serine/threonine kinase)
NEK9 NIMA-related kinase 9
NEU2 sialidase 2 (cytosolic sialidase)
NKX2-8 NK2 homeobox 8
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NRG1 neuregulin 1
NRSN2 neurensin 2
NRTN neurturin
PARVA parvin, alpha
PBX2 pre-B-cell leukemia homeobox 2
PCNXL2 pecanex-like 2 (Drosophila)
PDHA2 pyruvate dehydrogenase (lipoamide) alpha 2
PKNOX2 PBX/knotted 1 homeobox 2
PLXNA2 plexin A2
PORCN porcupine homolog (Drosophila)
PRDM12 PR domain containing 12
PRLH prolactin releasing hormone
RAB40AL RAB40A, member RAS oncogene family-like
RPL35A ribosomal protein L35a
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SFRP4 secreted frizzled-related protein 4
SH2D3A SH2 domain containing 3A
SIRT5 sirtuin 5
SKI SKI proto-oncogene
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SLIT1 slit homolog 1 (Drosophila)
SOX21 SRY (sex determining region Y)-box 21
SRSF5 serine/arginine-rich splicing factor 5
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TBL1Y transducin (beta)-like 1, Y-linked
TEF thyrotrophic embryonic factor
TEX14 testis expressed 14
TGM2 transglutaminase 2
TMEM63A transmembrane protein 63A
TRIM15 tripartite motif containing 15
TRIM3 tripartite motif containing 3
USP9Y ubiquitin specific peptidase 9, Y-linked
VAV2 vav 2 guanine nucleotide exchange factor
WDR62 WD repeat domain 62
XAF1 XIAP associated factor 1
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF419 zinc finger protein 419

decreased expression

Symbol Name
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ALG12 ALG12, alpha-1,6-mannosyltransferase
ATAT1 alpha tubulin acetyltransferase 1
AUTS2 autism susceptibility candidate 2
C11ORF30 chromosome 11 open reading frame 30
C14ORF79 chromosome 14 open reading frame 79
CALCOCO1 calcium binding and coiled-coil domain 1
CBX8 chromobox homolog 8
CCDC132 coiled-coil domain containing 132
CCDC71 coiled-coil domain containing 71
CES3 carboxylesterase 3
CFAP44 cilia and flagella associated protein 44
CHM choroideremia (Rab escort protein 1)
CLCF1 cardiotrophin-like cytokine factor 1
CLEC4E C-type lectin domain family 4, member E
CORT cortistatin
CRABP1 cellular retinoic acid binding protein 1
CRIP1 cysteine-rich protein 1 (intestinal)
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DOCK4 dedicator of cytokinesis 4
DRD1 dopamine receptor D1
DSPP dentin sialophosphoprotein
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EPN1 epsin 1
F8 coagulation factor VIII, procoagulant component
FAAH fatty acid amide hydrolase
FAM110B family with sequence similarity 110, member B
FAM155A family with sequence similarity 155, member A
FGF23 fibroblast growth factor 23
FLJ21369 uncharacterized protein FLJ21369
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GFI1 growth factor independent 1 transcription repressor
GLS2 glutaminase 2 (liver, mitochondrial)
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GPR27 G protein-coupled receptor 27
GPR3 G protein-coupled receptor 3
GRB7 growth factor receptor-bound protein 7
HAMP hepcidin antimicrobial peptide
HDAC5 histone deacetylase 5
HOXB2 homeobox B2
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
IFT140 intraflagellar transport 140
IFT81 intraflagellar transport 81
IGFBP6 insulin-like growth factor binding protein 6
IL12RB1 interleukin 12 receptor, beta 1
IL2 interleukin 2
IQCG IQ motif containing G
JMJD4 jumonji domain containing 4
KDM8 lysine (K)-specific demethylase 8
KLHL28 kelch-like family member 28
LOC100286895 cell division cycle 27 homolog pseudogene
LTBP2 latent transforming growth factor beta binding protein 2
MED15 mediator complex subunit 15
MEFV Mediterranean fever
MT1H metallothionein 1H
NACA2 nascent polypeptide-associated complex alpha subunit 2
NME5 NME/NM23 family member 5
OXCT2 3-oxoacid CoA transferase 2
PADI1 peptidyl arginine deiminase, type I
PAIP2B poly(A) binding protein interacting protein 2B
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PDE8B phosphodiesterase 8B
PDK4 pyruvate dehydrogenase kinase, isozyme 4
POM121L2 POM121 transmembrane nucleoporin-like 2
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PRSS53 protease, serine, 53
RAB3D RAB3D, member RAS oncogene family
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RNF122 ring finger protein 122
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RNF126P1 ring finger protein 126 pseudogene 1
RRAGB Ras-related GTP binding B
SAMD9 sterile alpha motif domain containing 9
SCGB2A2 secretoglobin, family 2A, member 2
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SOWAHC sosondowah ankyrin repeat domain family member C
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TSGA10 testis specific, 10
TTF2 transcription termination factor, RNA polymerase II
TUBA3C tubulin, alpha 3c
UPK3B uroplakin 3B
URM1 ubiquitin related modifier 1
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
ZFP37 ZFP37 zinc finger protein
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF304 zinc finger protein 304
ZNF32 zinc finger protein 32
ZNF446 zinc finger protein 446
ZNF506 zinc finger protein 506
ZNF606 zinc finger protein 606
ZNF711 zinc finger protein 711
ZNF750 zinc finger protein 750