fluspirilene-6463 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

197 genes differentially expressed following the fluspirilene-6463 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABI2 abl-interactor 2
ADAM12 ADAM metallopeptidase domain 12
ANG angiogenin, ribonuclease, RNase A family, 5
ARC activity-regulated cytoskeleton-associated protein
ARHGAP26 Rho GTPase activating protein 26
ARL14 ADP-ribosylation factor-like 14
ATF3 activating transcription factor 3
BAIAP2 BAI1-associated protein 2
BBC3 BCL2 binding component 3
BHLHE40 basic helix-loop-helix family, member e40
C5AR1 complement component 5a receptor 1
CCNG2 cyclin G2
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CTGF connective tissue growth factor
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
DAPK3 death-associated protein kinase 3
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DFNB31 deafness, autosomal recessive 31
DLX2 distal-less homeobox 2
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DUSP1 dual specificity phosphatase 1
DUSP4 dual specificity phosphatase 4
EGR1 early growth response 1
EGR2 early growth response 2
EGR3 early growth response 3
EGR4 early growth response 4
ERAP1 endoplasmic reticulum aminopeptidase 1
ERO1LB ERO1-like beta (S. cerevisiae)
FAM46C family with sequence similarity 46, member C
FBLN1 fibulin 1
FIGF c-fos induced growth factor (vascular endothelial growth factor D)
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FSCN1 fascin actin-bundling protein 1
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45B growth arrest and DNA-damage-inducible, beta
GEM GTP binding protein overexpressed in skeletal muscle
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIST1H3B histone cluster 1, H3b
IER2 immediate early response 2
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IL6 interleukin 6
INHBE inhibin, beta E
INSIG1 insulin induced gene 1
IRF1 interferon regulatory factor 1
ISG20 interferon stimulated exonuclease gene 20kDa
JUN jun proto-oncogene
JUNB jun B proto-oncogene
KLF2 Kruppel-like factor 2
KLF6 Kruppel-like factor 6
KLHL24 kelch-like family member 24
LDLR low density lipoprotein receptor
LPIN1 lipin 1
LRRC6 leucine rich repeat containing 6
LRRC75B leucine rich repeat containing 75B
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MCAM melanoma cell adhesion molecule
MT1F metallothionein 1F
MT1X metallothionein 1X
MVD mevalonate (diphospho) decarboxylase
MXD4 MAX dimerization protein 4
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
NEFM neurofilament, medium polypeptide
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NR4A3 nuclear receptor subfamily 4, group A, member 3
NSUN6 NOP2/Sun domain family, member 6
PDIA4 protein disulfide isomerase family A, member 4
PHLDA1 pleckstrin homology-like domain, family A, member 1
PIDD1 p53-induced death domain protein 1
PLCL2 phospholipase C-like 2
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
POMT2 protein-O-mannosyltransferase 2
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PRPH2 peripherin 2 (retinal degeneration, slow)
RAB11B RAB11B, member RAS oncogene family
RCAN1 regulator of calcineurin 1
RND1 Rho family GTPase 1
RNF122 ring finger protein 122
SARM1 sterile alpha and TIR motif containing 1
SAT1 spermidine/spermine N1-acetyltransferase 1
SCN10A sodium channel, voltage gated, type X alpha subunit
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLCO4C1 solute carrier organic anion transporter family, member 4C1
SOX9 SRY (sex determining region Y)-box 9
TEX14 testis expressed 14
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TRIM2 tripartite motif containing 2
TYRP1 tyrosinase-related protein 1
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)

decreased expression

Symbol Name
ABCA11P ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
AKAP12 A kinase (PRKA) anchor protein 12
ARMC7 armadillo repeat containing 7
AUTS2 autism susceptibility candidate 2
BAG4 BCL2-associated athanogene 4
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BMP15 bone morphogenetic protein 15
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C22ORF29 chromosome 22 open reading frame 29
C7ORF43 chromosome 7 open reading frame 43
C7ORF69 chromosome 7 open reading frame 69
CA2 carbonic anhydrase II
CENPO centromere protein O
CLDN17 claudin 17
CLSPN claspin
CNR2 cannabinoid receptor 2 (macrophage)
CORO1A coronin, actin binding protein, 1A
CTPS1 CTP synthase 1
CXXC4 CXXC finger protein 4
DCAF13 DDB1 and CUL4 associated factor 13
DCLRE1A DNA cross-link repair 1A
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DLEU2 deleted in lymphocytic leukemia 2 (non-protein coding)
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNM1 dynamin 1
DUSP2 dual specificity phosphatase 2
ENO2 enolase 2 (gamma, neuronal)
FAAH fatty acid amide hydrolase
FBXO22 F-box protein 22
FLT4 fms-related tyrosine kinase 4
GALK1 galactokinase 1
GLB1L2 galactosidase, beta 1-like 2
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HAUS6 HAUS augmin-like complex, subunit 6
HELLS helicase, lymphoid-specific
HMGB3P1 high mobility group box 3 pseudogene 1
HOOK1 hook microtubule-tethering protein 1
HOXC5 homeobox C5
HSPA1L heat shock 70kDa protein 1-like
HSPB6 heat shock protein, alpha-crystallin-related, B6
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IKZF5 IKAROS family zinc finger 5 (Pegasus)
KIAA0556 KIAA0556
KRT13 keratin 13, type I
L2HGDH L-2-hydroxyglutarate dehydrogenase
LOC729164 hCG1732469
LRRC61 leucine rich repeat containing 61
LYRM9 LYR motif containing 9
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MCTP1 multiple C2 domains, transmembrane 1
MECR mitochondrial trans-2-enoyl-CoA reductase
MXD3 MAX dimerization protein 3
NFE2L3 nuclear factor, erythroid 2-like 3
NLK nemo-like kinase
NOL12 nucleolar protein 12
NPY5R neuropeptide Y receptor Y5
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
ORC1 origin recognition complex, subunit 1
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PAIP2B poly(A) binding protein interacting protein 2B
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PHC1 polyhomeotic homolog 1 (Drosophila)
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PPT2 palmitoyl-protein thioesterase 2
PROCR protein C receptor, endothelial
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
RBM41 RNA binding motif protein 41
RCAN3 RCAN family member 3
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RP2 retinitis pigmentosa 2 (X-linked recessive)
RPL23AP32 ribosomal protein L23a pseudogene 32
SCYL2 SCY1-like 2 (S. cerevisiae)
SKI SKI proto-oncogene
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SLC41A3 solute carrier family 41, member 3
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
SYNC syncoilin, intermediate filament protein
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TMEM180 transmembrane protein 180
TMEM254 transmembrane protein 254
TOE1 target of EGR1, member 1 (nuclear)
TPST2 tyrosylprotein sulfotransferase 2
TRABD TraB domain containing
TRAIP TRAF interacting protein
TTLL1 tubulin tyrosine ligase-like family member 1
USP21 ubiquitin specific peptidase 21
VASH2 vasohibin 2
WDR76 WD repeat domain 76
ZBTB39 zinc finger and BTB domain containing 39
ZC3H3 zinc finger CCCH-type containing 3
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF324 zinc finger protein 324