| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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198 genes differentially expressed following the flutamide-2358 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) |
| ABI2 | abl-interactor 2 |
| ADORA1 | adenosine A1 receptor |
| AIRE | autoimmune regulator |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| AQP7 | aquaporin 7 |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| ARL4C | ADP-ribosylation factor-like 4C |
| ARRB1 | arrestin, beta 1 |
| ATP10B | ATPase, class V, type 10B |
| B3GNTL1 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1 |
| C1ORF61 | chromosome 1 open reading frame 61 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CADM3 | cell adhesion molecule 3 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CD82 | CD82 molecule |
| CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
| COL4A1 | collagen, type IV, alpha 1 |
| CSF2RA | colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) |
| CSRP2 | cysteine and glycine-rich protein 2 |
| DCLK2 | doublecortin-like kinase 2 |
| DCT | dopachrome tautomerase |
| DIMT1 | DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae) |
| DMC1 | DNA meiotic recombinase 1 |
| DOCK9 | dedicator of cytokinesis 9 |
| DUSP8 | dual specificity phosphatase 8 |
| E2F4 | E2F transcription factor 4, p107/p130-binding |
| EGR1 | early growth response 1 |
| EPHA1 | EPH receptor A1 |
| EPHB6 | EPH receptor B6 |
| EXOC7 | exocyst complex component 7 |
| FBLN1 | fibulin 1 |
| FGL1 | fibrinogen-like 1 |
| FTH1 | ferritin, heavy polypeptide 1 |
| FUS | FUS RNA binding protein |
| GATA3 | GATA binding protein 3 |
| GPR1 | G protein-coupled receptor 1 |
| GPX2 | glutathione peroxidase 2 |
| HTR1B | 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled |
| IFNA17 | interferon, alpha 17 |
| IGLJ3 | immunoglobulin lambda joining 3 |
| INPP1 | inositol polyphosphate-1-phosphatase |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| IVD | isovaleryl-CoA dehydrogenase |
| JAK3 | Janus kinase 3 |
| KIF1A | kinesin family member 1A |
| LARP4B | La ribonucleoprotein domain family, member 4B |
| LIMD2 | LIM domain containing 2 |
| LOC284244 | uncharacterized LOC284244 |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MAN1B1 | mannosidase, alpha, class 1B, member 1 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate |
| MARK4 | MAP/microtubule affinity-regulating kinase 4 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MOBP | myelin-associated oligodendrocyte basic protein |
| MYLK | myosin light chain kinase |
| MYO1C | myosin IC |
| NEB | nebulin |
| NFATC1 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| NRP1 | neuropilin 1 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PEG3 | paternally expressed 3 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) |
| PLK3 | polo-like kinase 3 |
| PPARD | peroxisome proliferator-activated receptor delta |
| PPM1H | protein phosphatase, Mg2+/Mn2+ dependent, 1H |
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma |
| PROL1 | proline rich, lacrimal 1 |
| PTAFR | platelet-activating factor receptor |
| RARA | retinoic acid receptor, alpha |
| RFPL3 | ret finger protein-like 3 |
| RGS19 | regulator of G-protein signaling 19 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RIN3 | Ras and Rab interactor 3 |
| RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 |
| RUFY3 | RUN and FYVE domain containing 3 |
| SCN2B | sodium channel, voltage gated, type II beta subunit |
| SH2B1 | SH2B adaptor protein 1 |
| SIDT2 | SID1 transmembrane family, member 2 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
| SLIT1 | slit homolog 1 (Drosophila) |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 |
| SSH3 | slingshot protein phosphatase 3 |
| SSX3 | synovial sarcoma, X breakpoint 3 |
| STC2 | stanniocalcin 2 |
| SYNJ2 | synaptojanin 2 |
| TBC1D30 | TBC1 domain family, member 30 |
| TEX261 | testis expressed 261 |
| TIMM8A | translocase of inner mitochondrial membrane 8 homolog A (yeast) |
| TLE3 | transducin-like enhancer of split 3 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 |
| TRIM23 | tripartite motif containing 23 |
| TSPYL2 | TSPY-like 2 |
| ZNF589 | zinc finger protein 589 |
| ZNF862 | zinc finger protein 862 |
| Symbol | Name |
|---|---|
| ACPP | acid phosphatase, prostate |
| ACTR3B | ARP3 actin-related protein 3 homolog B (yeast) |
| AEN | apoptosis enhancing nuclease |
| AGO4 | argonaute RISC catalytic component 4 |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 |
| AHCTF1 | AT hook containing transcription factor 1 |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| APOL6 | apolipoprotein L, 6 |
| ARMC7 | armadillo repeat containing 7 |
| ARNTL2 | aryl hydrocarbon receptor nuclear translocator-like 2 |
| ATG2B | autophagy related 2B |
| ATPAF2 | ATP synthase mitochondrial F1 complex assembly factor 2 |
| BMP15 | bone morphogenetic protein 15 |
| BTN3A3 | butyrophilin, subfamily 3, member A3 |
| C3 | complement component 3 |
| C6ORF47 | chromosome 6 open reading frame 47 |
| CAPN5 | calpain 5 |
| CCDC6 | coiled-coil domain containing 6 |
| CCR2 | chemokine (C-C motif) receptor 2 |
| CD244 | CD244 molecule, natural killer cell receptor 2B4 |
| CDK3 | cyclin-dependent kinase 3 |
| CEP70 | centrosomal protein 70kDa |
| CHMP1A | charged multivesicular body protein 1A |
| CHRNA5 | cholinergic receptor, nicotinic, alpha 5 (neuronal) |
| COG4 | component of oligomeric golgi complex 4 |
| CYSLTR1 | cysteinyl leukotriene receptor 1 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa |
| DEPDC1 | DEP domain containing 1 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| DPY19L2P2 | DPY19L2 pseudogene 2 |
| DYM | dymeclin |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| FADS2 | fatty acid desaturase 2 |
| FCHSD2 | FCH and double SH3 domains 2 |
| HIST2H2BE | histone cluster 2, H2be |
| HS1BP3 | HCLS1 binding protein 3 |
| ICK | intestinal cell (MAK-like) kinase |
| IFT46 | intraflagellar transport 46 |
| IFT81 | intraflagellar transport 81 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| KCNA3 | potassium channel, voltage gated shaker related subfamily A, member 3 |
| LXN | latexin |
| MANSC1 | MANSC domain containing 1 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 |
| MAPK3 | mitogen-activated protein kinase 3 |
| METTL16 | methyltransferase like 16 |
| METTL2B | methyltransferase like 2B |
| MILR1 | mast cell immunoglobulin-like receptor 1 |
| MITF | microphthalmia-associated transcription factor |
| MLPH | melanophilin |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| NARFL | nuclear prelamin A recognition factor-like |
| NPFFR1 | neuropeptide FF receptor 1 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| OSBPL11 | oxysterol binding protein-like 11 |
| OTUD3 | OTU deubiquitinase 3 |
| PAQR4 | progestin and adipoQ receptor family member IV |
| PDE6C | phosphodiesterase 6C, cGMP-specific, cone, alpha prime |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
| PIR | pirin (iron-binding nuclear protein) |
| PITRM1 | pitrilysin metallopeptidase 1 |
| PMCH | pro-melanin-concentrating hormone |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RAB5B | RAB5B, member RAS oncogene family |
| RBM4B | RNA binding motif protein 4B |
| RFXAP | regulatory factor X-associated protein |
| RIN1 | Ras and Rab interactor 1 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 |
| SMR3A | submaxillary gland androgen regulated protein 3A |
| SNX15 | sorting nexin 15 |
| SYNJ2BP | synaptojanin 2 binding protein |
| TBCCD1 | TBCC domain containing 1 |
| TBX19 | T-box 19 |
| TESK1 | testis-specific kinase 1 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TMEM134 | transmembrane protein 134 |
| TMEM254 | transmembrane protein 254 |
| TMEM39B | transmembrane protein 39B |
| TMEM57 | transmembrane protein 57 |
| TNRC6B | trinucleotide repeat containing 6B |
| TOR4A | torsin family 4, member A |
| TPCN1 | two pore segment channel 1 |
| TRIM26 | tripartite motif containing 26 |
| TSPAN32 | tetraspanin 32 |
| TTPAL | tocopherol (alpha) transfer protein-like |
| TXNDC15 | thioredoxin domain containing 15 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| WT1-AS | WT1 antisense RNA |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF552 | zinc finger protein 552 |
| ZNF668 | zinc finger protein 668 |
| ZSCAN31 | zinc finger and SCAN domain containing 31 |