flutamide-3885 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the flutamide-3885 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGRB1 adhesion G protein-coupled receptor B1
AEBP1 AE binding protein 1
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
APAF1 apoptotic peptidase activating factor 1
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1
BAX BCL2-associated X protein
C17ORF53 chromosome 17 open reading frame 53
C3ORF18 chromosome 3 open reading frame 18
CAPN2 calpain 2, (m/II) large subunit
CARTPT CART prepropeptide
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCRL2 chemokine (C-C motif) receptor-like 2
CD22 CD22 molecule
CELF2 CUGBP, Elav-like family member 2
CEP250 centrosomal protein 250kDa
CPQ carboxypeptidase Q
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CTSS cathepsin S
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DOCK9 dedicator of cytokinesis 9
DUSP4 dual specificity phosphatase 4
EDN1 endothelin 1
ELAVL3 ELAV like neuron-specific RNA binding protein 3
FABP3 fatty acid binding protein 3, muscle and heart
FBLN1 fibulin 1
FGD2 FYVE, RhoGEF and PH domain containing 2
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
GAB1 GRB2-associated binding protein 1
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GPR137 G protein-coupled receptor 137
GPR63 G protein-coupled receptor 63
GREB1L growth regulation by estrogen in breast cancer-like
GRK5 G protein-coupled receptor kinase 5
HAMP hepcidin antimicrobial peptide
HEMK1 HemK methyltransferase family member 1
HFE hemochromatosis
HIRA histone cell cycle regulator
HMGB3P1 high mobility group box 3 pseudogene 1
HMGN5 high mobility group nucleosome binding domain 5
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFITM1 interferon induced transmembrane protein 1
IGHA1 immunoglobulin heavy constant alpha 1
IGKV1D-13 immunoglobulin kappa variable 1D-13
IL1B interleukin 1, beta
INSL4 insulin-like 4 (placenta)
IPW imprinted in Prader-Willi syndrome (non-protein coding)
KLF13 Kruppel-like factor 13
KLRB1 killer cell lectin-like receptor subfamily B, member 1
LAT2 linker for activation of T cells family, member 2
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LY86 lymphocyte antigen 86
MAGEA3 melanoma antigen family A3
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MEGF6 multiple EGF-like-domains 6
MMP11 matrix metallopeptidase 11
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MMP25 matrix metallopeptidase 25
MOB1A MOB kinase activator 1A
MTL5 metallothionein-like 5, testis-specific (tesmin)
NR6A1 nuclear receptor subfamily 6, group A, member 1
PAPPA2 pappalysin 2
PAX8 paired box 8
PCDHB6 protocadherin beta 6
PCDHGA3 protocadherin gamma subfamily A, 3
PCLO piccolo presynaptic cytomatrix protein
PDE4C phosphodiesterase 4C, cAMP-specific
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PKP2 plakophilin 2
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PQLC2 PQ loop repeat containing 2
PRKD3 protein kinase D3
RAB3B RAB3B, member RAS oncogene family
SIRT5 sirtuin 5
SKIL SKI-like proto-oncogene
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
STAT4 signal transducer and activator of transcription 4
SUN1 Sad1 and UNC84 domain containing 1
TACC1 transforming, acidic coiled-coil containing protein 1
TAPBPL TAP binding protein-like
TBC1D22A TBC1 domain family, member 22A
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TEF thyrotrophic embryonic factor
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TPP1 tripeptidyl peptidase I
TRA2A transformer 2 alpha homolog (Drosophila)
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1
TRIL TLR4 interactor with leucine-rich repeats
UHRF1BP1L UHRF1 binding protein 1-like
VCAN versican
WSCD1 WSC domain containing 1
ZDHHC17 zinc finger, DHHC-type containing 17
ZFP36L1 ZFP36 ring finger protein-like 1

decreased expression

Symbol Name
ACBD4 acyl-CoA binding domain containing 4
AFAP1 actin filament associated protein 1
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
BGLAP bone gamma-carboxyglutamate (gla) protein
BIRC7 baculoviral IAP repeat containing 7
C8ORF60 chromosome 8 open reading frame 60
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CCDC69 coiled-coil domain containing 69
CCNK cyclin K
CD82 CD82 molecule
CEMIP cell migration inducing protein, hyaluronan binding
CEP97 centrosomal protein 97kDa
CNGB3 cyclic nucleotide gated channel beta 3
CORT cortistatin
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DRD1 dopamine receptor D1
EPHX2 epoxide hydrolase 2, cytoplasmic
FAM131A family with sequence similarity 131, member A
FAM198B family with sequence similarity 198, member B
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GEM GTP binding protein overexpressed in skeletal muscle
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GLB1L galactosidase, beta 1-like
HDAC11 histone deacetylase 11
HDAC5 histone deacetylase 5
HIST1H2AI histone cluster 1, H2ai
HOXC10 homeobox C10
HOXC4 homeobox C4
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IL12RB1 interleukin 12 receptor, beta 1
IQSEC2 IQ motif and Sec7 domain 2
KCNK12 potassium channel, two pore domain subfamily K, member 12
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KIAA1107 KIAA1107
KLK8 kallikrein-related peptidase 8
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MALL mal, T-cell differentiation protein-like
MAOB monoamine oxidase B
MAST3 microtubule associated serine/threonine kinase 3
MED15 mediator complex subunit 15
MFAP2 microfibrillar-associated protein 2
MMP17 matrix metallopeptidase 17 (membrane-inserted)
MTMR6 myotubularin related protein 6
MUM1 melanoma associated antigen (mutated) 1
NDRG4 NDRG family member 4
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NPIPB15 nuclear pore complex interacting protein family, member B15
NPTX1 neuronal pentraxin I
PMEL premelanosome protein
POLH polymerase (DNA directed), eta
PRAMEF11 PRAME family member 11
PRSS22 protease, serine, 22
PRSS53 protease, serine, 53
PTDSS2 phosphatidylserine synthase 2
QPCT glutaminyl-peptide cyclotransferase
RAB3A RAB3A, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RFXAP regulatory factor X-associated protein
RHOBTB2 Rho-related BTB domain containing 2
ROM1 retinal outer segment membrane protein 1
RPL13P5 ribosomal protein L13 pseudogene 5
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SIGLEC15 sialic acid binding Ig-like lectin 15
SLC22A14 solute carrier family 22, member 14
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SMYD5 SMYD family member 5
SPON2 spondin 2, extracellular matrix protein
TBC1D2 TBC1 domain family, member 2
TCP10 t-complex 10
TESC tescalcin
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TH tyrosine hydroxylase
TMEM180 transmembrane protein 180
TMEM254 transmembrane protein 254
TRABD TraB domain containing
TSC22D4 TSC22 domain family, member 4
TTBK2 tau tubulin kinase 2
TTLL1 tubulin tyrosine ligase-like family member 1
WDR33 WD repeat domain 33
WFDC2 WAP four-disulfide core domain 2
WNT16 wingless-type MMTV integration site family, member 16
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZIC3 Zic family member 3
ZNF134 zinc finger protein 134
ZNF204P zinc finger protein 204, pseudogene
ZNF219 zinc finger protein 219
ZNF423 zinc finger protein 423
ZNF446 zinc finger protein 446