flutamide-4361 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the flutamide-4361 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
APC adenomatous polyposis coli
BCL2 B-cell CLL/lymphoma 2
BTNL3 butyrophilin-like 3
C19ORF73 chromosome 19 open reading frame 73
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit
CASP10 caspase 10, apoptosis-related cysteine peptidase
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CFAP69 cilia and flagella associated protein 69
CFAP70 cilia and flagella associated protein 70
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CRHR2 corticotropin releasing hormone receptor 2
CST4 cystatin S
CTIF CBP80/20-dependent translation initiation factor
DAO D-amino-acid oxidase
DGKG diacylglycerol kinase, gamma 90kDa
EIF3F eukaryotic translation initiation factor 3, subunit F
EIF5A eukaryotic translation initiation factor 5A
ERBB2 erb-b2 receptor tyrosine kinase 2
F13A1 coagulation factor XIII, A1 polypeptide
FAM189A1 family with sequence similarity 189, member A1
FBXL7 F-box and leucine-rich repeat protein 7
FGF6 fibroblast growth factor 6
FMO5 flavin containing monooxygenase 5
FRMD1 FERM domain containing 1
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GP2 glycoprotein 2 (zymogen granule membrane)
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
HIST1H4C histone cluster 1, H4c
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
ICOSLG inducible T-cell co-stimulator ligand
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IGL immunoglobulin lambda locus
INHBA inhibin, beta A
INHBC inhibin, beta C
JAG1 jagged 1
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KLRD1 killer cell lectin-like receptor subfamily D, member 1
KRT8 keratin 8, type II
LAT2 linker for activation of T cells family, member 2
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MEP1B meprin A, beta
MIER2 mesoderm induction early response 1, family member 2
MNDA myeloid cell nuclear differentiation antigen
MORN1 MORN repeat containing 1
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MTA2 metastasis associated 1 family, member 2
MXD4 MAX dimerization protein 4
NEURL1 neuralized E3 ubiquitin protein ligase 1
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NPY neuropeptide Y
NTS neurotensin
OPRM1 opioid receptor, mu 1
OSBPL10 oxysterol binding protein-like 10
PCDHA10 protocadherin alpha 10
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLCD1 phospholipase C, delta 1
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
PRDM1 PR domain containing 1, with ZNF domain
RAB6B RAB6B, member RAS oncogene family
RAP2B RAP2B, member of RAS oncogene family
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RELN reelin
RFPL3 ret finger protein-like 3
RPGRIP1L RPGRIP1-like
SCN11A sodium channel, voltage gated, type XI alpha subunit
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
SEMG2 semenogelin II
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
SIGLEC8 sialic acid binding Ig-like lectin 8
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC14A2 solute carrier family 14 (urea transporter), member 2
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5)
SPON1 spondin 1, extracellular matrix protein
SPTBN1 spectrin, beta, non-erythrocytic 1
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
T T, brachyury homolog (mouse)
TGFBR1 transforming growth factor, beta receptor 1
TMEM206 transmembrane protein 206
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TRD T cell receptor delta locus
TTC38 tetratricopeptide repeat domain 38
TUBB7P tubulin, beta 7, pseudogene
UBR2 ubiquitin protein ligase E3 component n-recognin 2
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
UTS2 urotensin 2
VCAN versican
VN1R1 vomeronasal 1 receptor 1
WIPF1 WAS/WASL interacting protein family, member 1
ZNF202 zinc finger protein 202
ZNF24 zinc finger protein 24
ZXDB zinc finger, X-linked, duplicated B

decreased expression

Symbol Name
ADAM15 ADAM metallopeptidase domain 15
AKT2 v-akt murine thymoma viral oncogene homolog 2
ANKRD36B ankyrin repeat domain 36B
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARPIN actin-related protein 2/3 complex inhibitor
ASAP1-IT1 ASAP1 intronic transcript 1
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
ATHL1 ATH1, acid trehalase-like 1 (yeast)
C2ORF27A chromosome 2 open reading frame 27A
CAMK1 calcium/calmodulin-dependent protein kinase I
CBX2 chromobox homolog 2
CCDC186 coiled-coil domain containing 186
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CHD8 chromodomain helicase DNA binding protein 8
CUEDC1 CUE domain containing 1
CUZD1 CUB and zona pellucida-like domains 1
DACH1 dachshund family transcription factor 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DCAF16 DDB1 and CUL4 associated factor 16
DLK2 delta-like 2 homolog (Drosophila)
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
DUSP8 dual specificity phosphatase 8
ELP6 elongator acetyltransferase complex subunit 6
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
ERCC2 excision repair cross-complementation group 2
ERN2 endoplasmic reticulum to nucleus signaling 2
ESF1 ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)
EXD3 exonuclease 3'-5' domain containing 3
FAM169A family with sequence similarity 169, member A
FKBP10 FK506 binding protein 10, 65 kDa
FKBP5 FK506 binding protein 5
FLJ11710 uncharacterized protein FLJ11710
FRMD4A FERM domain containing 4A
G6PD glucose-6-phosphate dehydrogenase
GATA4 GATA binding protein 4
GRAMD1C GRAM domain containing 1C
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
INO80D INO80 complex subunit D
KDM8 lysine (K)-specific demethylase 8
KIFC1 kinesin family member C1
KLHL25 kelch-like family member 25
KREMEN2 kringle containing transmembrane protein 2
KRT24 keratin 24, type I
LOC157562 uncharacterized LOC157562
LRRC8E leucine rich repeat containing 8 family, member E
MBOAT2 membrane bound O-acyltransferase domain containing 2
METTL16 methyltransferase like 16
MIS18BP1 MIS18 binding protein 1
MTCP1 mature T-cell proliferation 1
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit
NCALD neurocalcin delta
NDE1 nudE neurodevelopment protein 1
NPM3 nucleophosmin/nucleoplasmin 3
NR1D2 nuclear receptor subfamily 1, group D, member 2
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1
ONECUT2 one cut homeobox 2
PACS1 phosphofurin acidic cluster sorting protein 1
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PLEKHS1 pleckstrin homology domain containing, family S member 1
RAB40C RAB40C, member RAS oncogene family
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RASA2 RAS p21 protein activator 2
RND1 Rho family GTPase 1
RNF126P1 ring finger protein 126 pseudogene 1
RPL10L ribosomal protein L10-like
S100A7 S100 calcium binding protein A7
SCARA3 scavenger receptor class A, member 3
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SKI SKI proto-oncogene
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SPIN1 spindlin 1
STON1 stonin 1
TM6SF1 transmembrane 6 superfamily member 1
TMEM209 transmembrane protein 209
TMEM260 transmembrane protein 260
TRAF4 TNF receptor-associated factor 4
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TSPAN5 tetraspanin 5
USP27X ubiquitin specific peptidase 27, X-linked
VASH2 vasohibin 2
VWA1 von Willebrand factor A domain containing 1
WWC2 WW and C2 domain containing 2
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
ZBTB38 zinc finger and BTB domain containing 38
ZIC3 Zic family member 3
ZNF350 zinc finger protein 350
ZNF675 zinc finger protein 675
ZNF747 zinc finger protein 747
ZNF770 zinc finger protein 770
ZNF862 zinc finger protein 862
ZSWIM1 zinc finger, SWIM-type containing 1