| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the fluticasone-4011 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ACSM3 | acyl-CoA synthetase medium-chain family member 3 |
| AKR1D1 | aldo-keto reductase family 1, member D1 |
| ALOXE3 | arachidonate lipoxygenase 3 |
| AOC3 | amine oxidase, copper containing 3 |
| APOBEC3F | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F |
| APPBP2 | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 |
| ATF5 | activating transcription factor 5 |
| B3GNTL1 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1 |
| BMP3 | bone morphogenetic protein 3 |
| C17ORF70 | chromosome 17 open reading frame 70 |
| CASR | calcium-sensing receptor |
| CASS4 | Cas scaffolding protein family member 4 |
| CD33 | CD33 molecule |
| CD6 | CD6 molecule |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) |
| CR1 | complement component (3b/4b) receptor 1 (Knops blood group) |
| CSF1R | colony stimulating factor 1 receptor |
| CYP2U1 | cytochrome P450, family 2, subfamily U, polypeptide 1 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 |
| DTX3 | deltex 3, E3 ubiquitin ligase |
| DUSP1 | dual specificity phosphatase 1 |
| E2F5 | E2F transcription factor 5, p130-binding |
| EGR1 | early growth response 1 |
| ETV1 | ets variant 1 |
| EXOG | endo/exonuclease (5'-3'), endonuclease G-like |
| FETUB | fetuin B |
| FILIP1L | filamin A interacting protein 1-like |
| FKBP5 | FK506 binding protein 5 |
| GAS2 | growth arrest-specific 2 |
| GJA8 | gap junction protein, alpha 8, 50kDa |
| GTDC1 | glycosyltransferase-like domain containing 1 |
| GYPB | glycophorin B (MNS blood group) |
| HES2 | hes family bHLH transcription factor 2 |
| HIST1H2AL | histone cluster 1, H2al |
| HLF | hepatic leukemia factor |
| HTR7 | 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled |
| IGHA1 | immunoglobulin heavy constant alpha 1 |
| IL18R1 | interleukin 18 receptor 1 |
| KDELR3 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 |
| KIAA1109 | KIAA1109 |
| KRT31 | keratin 31, type I |
| MAN2A2 | mannosidase, alpha, class 2A, member 2 |
| MME | membrane metallo-endopeptidase |
| MPPE1 | metallophosphoesterase 1 |
| MRAS | muscle RAS oncogene homolog |
| MT1F | metallothionein 1F |
| MT1HL1 | metallothionein 1H-like 1 |
| MT1X | metallothionein 1X |
| MTMR3 | myotubularin related protein 3 |
| NF1 | neurofibromin 1 |
| NME8 | NME/NM23 family member 8 |
| NNMT | nicotinamide N-methyltransferase |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| P2RX7 | purinergic receptor P2X, ligand gated ion channel, 7 |
| P2RY11 | purinergic receptor P2Y, G-protein coupled, 11 |
| PATZ1 | POZ (BTB) and AT hook containing zinc finger 1 |
| PBOV1 | prostate and breast cancer overexpressed 1 |
| PER1 | period circadian clock 1 |
| PHTF2 | putative homeodomain transcription factor 2 |
| PKD2L2 | polycystic kidney disease 2-like 2 |
| PLAT | plasminogen activator, tissue |
| PLVAP | plasmalemma vesicle associated protein |
| PRAMEF11 | PRAME family member 11 |
| PROC | protein C (inactivator of coagulation factors Va and VIIIa) |
| PSD4 | pleckstrin and Sec7 domain containing 4 |
| PTPRCAP | protein tyrosine phosphatase, receptor type, C-associated protein |
| PTPRR | protein tyrosine phosphatase, receptor type, R |
| QPCT | glutaminyl-peptide cyclotransferase |
| R3HDM1 | R3H domain containing 1 |
| RASAL2 | RAS protein activator like 2 |
| RNGTT | RNA guanylyltransferase and 5'-phosphatase |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
| SIGLEC8 | sialic acid binding Ig-like lectin 8 |
| SIX3 | SIX homeobox 3 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 |
| SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 |
| SLC9A3 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 |
| SNAI2 | snail family zinc finger 2 |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SOX5 | SRY (sex determining region Y)-box 5 |
| SRSF5 | serine/arginine-rich splicing factor 5 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 |
| STATH | statherin |
| TACSTD2 | tumor-associated calcium signal transducer 2 |
| TADA2A | transcriptional adaptor 2A |
| TLE2 | transducin-like enhancer of split 2 |
| TNNT3 | troponin T type 3 (skeletal, fast) |
| TRPC4 | transient receptor potential cation channel, subfamily C, member 4 |
| TSR3 | TSR3, 20S rRNA accumulation, homolog (S. cerevisiae) |
| UBE2B | ubiquitin-conjugating enzyme E2B |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) |
| VARS | valyl-tRNA synthetase |
| XYLB | xylulokinase homolog (H. influenzae) |
| YIPF2 | Yip1 domain family, member 2 |
| ZNF155 | zinc finger protein 155 |
| ZNF334 | zinc finger protein 334 |
| ZSWIM1 | zinc finger, SWIM-type containing 1 |
| Symbol | Name |
|---|---|
| ABCA3 | ATP-binding cassette, sub-family A (ABC1), member 3 |
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 |
| AFF4 | AF4/FMR2 family, member 4 |
| AGMAT | agmatine ureohydrolase (agmatinase) |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| AOC2 | amine oxidase, copper containing 2 (retina-specific) |
| ARID3A | AT rich interactive domain 3A (BRIGHT-like) |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| ARMCX4 | armadillo repeat containing, X-linked 4 |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| BST1 | bone marrow stromal cell antigen 1 |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| C5ORF42 | chromosome 5 open reading frame 42 |
| CA9 | carbonic anhydrase IX |
| CADPS2 | Ca++-dependent secretion activator 2 |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CDH7 | cadherin 7, type 2 |
| CDK3 | cyclin-dependent kinase 3 |
| CLDN15 | claudin 15 |
| CLEC2B | C-type lectin domain family 2, member B |
| COG4 | component of oligomeric golgi complex 4 |
| CRMP1 | collapsin response mediator protein 1 |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| CXCL6 | chemokine (C-X-C motif) ligand 6 |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DLK2 | delta-like 2 homolog (Drosophila) |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| DNM3 | dynamin 3 |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| ERO1LB | ERO1-like beta (S. cerevisiae) |
| ETNK2 | ethanolamine kinase 2 |
| EXOC6B | exocyst complex component 6B |
| EYA4 | EYA transcriptional coactivator and phosphatase 4 |
| FAM186A | family with sequence similarity 186, member A |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 |
| GUCY1A2 | guanylate cyclase 1, soluble, alpha 2 |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| HIST2H2AA3 | histone cluster 2, H2aa3 |
| HSPA1L | heat shock 70kDa protein 1-like |
| IFI44L | interferon-induced protein 44-like |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| IL17RB | interleukin 17 receptor B |
| IL1B | interleukin 1, beta |
| KDM7A | lysine (K)-specific demethylase 7A |
| KRT86 | keratin 86, type II |
| LMTK1 | lemur tail kinase 1 |
| LOC729164 | hCG1732469 |
| LPPR4 | lipid phosphate phosphatase-related protein type 4 |
| LRRC61 | leucine rich repeat containing 61 |
| MAMLD1 | mastermind-like domain containing 1 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MCTP2 | multiple C2 domains, transmembrane 2 |
| MLYCD | malonyl-CoA decarboxylase |
| MMP3 | matrix metallopeptidase 3 |
| MNMIP1 | manchette microtubule inner protein 1 |
| MRPL52 | mitochondrial ribosomal protein L52 |
| MYO1E | myosin IE |
| NAALAD2 | N-acetylated alpha-linked acidic dipeptidase 2 |
| NDRG4 | NDRG family member 4 |
| NIPAL2 | NIPA-like domain containing 2 |
| NME3 | NME/NM23 nucleoside diphosphate kinase 3 |
| NPY1R | neuropeptide Y receptor Y1 |
| NR3C2 | nuclear receptor subfamily 3, group C, member 2 |
| OBSCN | obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PALMD | palmdelphin |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PLAU | plasminogen activator, urokinase |
| PLD3 | phospholipase D family, member 3 |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| POLL | polymerase (DNA directed), lambda |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| PRPH | peripherin |
| PSORS1C1 | psoriasis susceptibility 1 candidate 1 |
| QSER1 | glutamine and serine rich 1 |
| RABL6 | RAB, member RAS oncogene family-like 6 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SLC9A5 | solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 |
| SLITRK5 | SLIT and NTRK-like family, member 5 |
| SSTR4 | somatostatin receptor 4 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| STAB2 | stabilin 2 |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TAOK1 | TAO kinase 1 |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TRIM9 | tripartite motif containing 9 |
| TSPYL2 | TSPY-like 2 |
| ZNF141 | zinc finger protein 141 |
| ZNF268 | zinc finger protein 268 |
| ZNF528 | zinc finger protein 528 |
| ZNF747 | zinc finger protein 747 |
