| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the fluticasone-4129 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 |
| ADAP2 | ArfGAP with dual PH domains 2 |
| ADGRL1 | adhesion G protein-coupled receptor L1 |
| ANXA2P1 | annexin A2 pseudogene 1 |
| ARAP1 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 |
| ARRB1 | arrestin, beta 1 |
| ASAP3 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 |
| ASCL1 | achaete-scute family bHLH transcription factor 1 |
| ATAD3A | ATPase family, AAA domain containing 3A |
| ATN1 | atrophin 1 |
| BCL6 | B-cell CLL/lymphoma 6 |
| BNC2 | basonuclin 2 |
| BTNL3 | butyrophilin-like 3 |
| CALCR | calcitonin receptor |
| CASKIN2 | CASK interacting protein 2 |
| CD1C | CD1c molecule |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CDK14 | cyclin-dependent kinase 14 |
| CDO1 | cysteine dioxygenase type 1 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CLDN17 | claudin 17 |
| COMT | catechol-O-methyltransferase |
| CRAT | carnitine O-acetyltransferase |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa |
| CUL3 | cullin 3 |
| CXORF21 | chromosome X open reading frame 21 |
| CYP4F12 | cytochrome P450, family 4, subfamily F, polypeptide 12 |
| DLK2 | delta-like 2 homolog (Drosophila) |
| EFNB3 | ephrin-B3 |
| EGR1 | early growth response 1 |
| ESRRA | estrogen-related receptor alpha |
| FANCE | Fanconi anemia, complementation group E |
| FBXO2 | F-box protein 2 |
| FLOT1 | flotillin 1 |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GLDC | glycine dehydrogenase (decarboxylating) |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) |
| GPR137 | G protein-coupled receptor 137 |
| HSPG2 | heparan sulfate proteoglycan 2 |
| IGHG1 | immunoglobulin heavy constant gamma 1 (G1m marker) |
| INHA | inhibin, alpha |
| ITGB5 | integrin, beta 5 |
| KIAA1107 | KIAA1107 |
| KLF9 | Kruppel-like factor 9 |
| LMTK1 | lemur tail kinase 1 |
| LRRC40 | leucine rich repeat containing 40 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| MAG | myelin associated glycoprotein |
| MALL | mal, T-cell differentiation protein-like |
| MAP4K2 | mitogen-activated protein kinase kinase kinase kinase 2 |
| MUC1 | mucin 1, cell surface associated |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist |
| NOL10 | nucleolar protein 10 |
| NPC1 | Niemann-Pick disease, type C1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NRP1 | neuropilin 1 |
| OPCML | opioid binding protein/cell adhesion molecule-like |
| OSBPL2 | oxysterol binding protein-like 2 |
| PAM | peptidylglycine alpha-amidating monooxygenase |
| PER1 | period circadian clock 1 |
| PKNOX2 | PBX/knotted 1 homeobox 2 |
| PLAC4 | placenta-specific 4 |
| PLXNB3 | plexin B3 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PQBP1 | polyglutamine binding protein 1 |
| PRSS22 | protease, serine, 22 |
| PSCA | prostate stem cell antigen |
| PTPRCAP | protein tyrosine phosphatase, receptor type, C-associated protein |
| RANBP3 | RAN binding protein 3 |
| RECQL5 | RecQ protein-like 5 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| RRBP1 | ribosome binding protein 1 |
| S100A13 | S100 calcium binding protein A13 |
| SEMA4G | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G |
| SERHL2 | serine hydrolase-like 2 |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 |
| SLC27A6 | solute carrier family 27 (fatty acid transporter), member 6 |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SOGA1 | suppressor of glucose, autophagy associated 1 |
| SREBF2 | sterol regulatory element binding transcription factor 2 |
| SRRM2 | serine/arginine repetitive matrix 2 |
| SSX3 | synovial sarcoma, X breakpoint 3 |
| ST3GAL4 | ST3 beta-galactoside alpha-2,3-sialyltransferase 4 |
| STS | steroid sulfatase (microsomal), isozyme S |
| TBR1 | T-box, brain, 1 |
| TFAP2A | transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) |
| TFG | TRK-fused gene |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TRIM3 | tripartite motif containing 3 |
| TSC22D4 | TSC22 domain family, member 4 |
| WNK1 | WNK lysine deficient protein kinase 1 |
| ZNF528 | zinc finger protein 528 |
| ZNF589 | zinc finger protein 589 |
| ZNF609 | zinc finger protein 609 |
| ZNF639 | zinc finger protein 639 |
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| AMH | anti-Mullerian hormone |
| ANKRD2 | ankyrin repeat domain 2 (stretch responsive muscle) |
| ARHGEF26 | Rho guanine nucleotide exchange factor (GEF) 26 |
| ASIC3 | acid sensing (proton gated) ion channel 3 |
| BAGE | B melanoma antigen |
| BLNK | B-cell linker |
| BMP15 | bone morphogenetic protein 15 |
| BMP4 | bone morphogenetic protein 4 |
| BRINP2 | bone morphogenetic protein/retinoic acid inducible neural-specific 2 |
| C22ORF29 | chromosome 22 open reading frame 29 |
| CEL | carboxyl ester lipase |
| CENPO | centromere protein O |
| CFAP45 | cilia and flagella associated protein 45 |
| CHM | choroideremia (Rab escort protein 1) |
| CHST1 | carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 |
| CLSPN | claspin |
| CPA4 | carboxypeptidase A4 |
| CTAGE1 | cutaneous T-cell lymphoma-associated antigen 1 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| CYP4F11 | cytochrome P450, family 4, subfamily F, polypeptide 11 |
| DENND5B | DENN/MADD domain containing 5B |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DPF3 | D4, zinc and double PHD fingers, family 3 |
| DUSP13 | dual specificity phosphatase 13 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| ECM1 | extracellular matrix protein 1 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| EPX | eosinophil peroxidase |
| ERCC2 | excision repair cross-complementation group 2 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FGL1 | fibrinogen-like 1 |
| FLJ21369 | uncharacterized protein FLJ21369 |
| FRMD1 | FERM domain containing 1 |
| FZD10 | frizzled class receptor 10 |
| GPATCH2L | G patch domain containing 2-like |
| GRIP2 | glutamate receptor interacting protein 2 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H2BN | histone cluster 1, H2bn |
| HMOX1 | heme oxygenase 1 |
| HOXC8 | homeobox C8 |
| HS3ST2 | heparan sulfate (glucosamine) 3-O-sulfotransferase 2 |
| HSPA2 | heat shock 70kDa protein 2 |
| HSPB6 | heat shock protein, alpha-crystallin-related, B6 |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| IBSP | integrin-binding sialoprotein |
| INO80D | INO80 complex subunit D |
| IPO8 | importin 8 |
| KIAA0754 | KIAA0754 |
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog |
| KRT31 | keratin 31, type I |
| KRT83 | keratin 83, type II |
| LATS1 | large tumor suppressor kinase 1 |
| LPPR1 | lipid phosphate phosphatase-related protein type 1 |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| LTC4S | leukotriene C4 synthase |
| MATK | megakaryocyte-associated tyrosine kinase |
| MST1 | macrophage stimulating 1 |
| MTA2 | metastasis associated 1 family, member 2 |
| NDUFAF5 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 5 |
| NOTCH4 | notch 4 |
| NPR3 | natriuretic peptide receptor 3 |
| NPY6R | neuropeptide Y receptor Y6 (pseudogene) |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| OCA2 | oculocutaneous albinism II |
| PARD6B | par-6 family cell polarity regulator beta |
| PDE8B | phosphodiesterase 8B |
| PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
| PLCD1 | phospholipase C, delta 1 |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PRKAB2 | protein kinase, AMP-activated, beta 2 non-catalytic subunit |
| PRR14L | proline rich 14-like |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| RAB30 | RAB30, member RAS oncogene family |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 |
| RCAN3 | RCAN family member 3 |
| RFXAP | regulatory factor X-associated protein |
| RNF122 | ring finger protein 122 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| SCG2 | secretogranin II |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SLC26A6 | solute carrier family 26 (anion exchanger), member 6 |
| SP1 | Sp1 transcription factor |
| SPRR1B | small proline-rich protein 1B |
| TAS2R10 | taste receptor, type 2, member 10 |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| THBS3 | thrombospondin 3 |
| TRIM25 | tripartite motif containing 25 |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 |
| UCN | urocortin |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| ZNF423 | zinc finger protein 423 |
| ZNF586 | zinc finger protein 586 |
| ZNF747 | zinc finger protein 747 |
| ZNF750 | zinc finger protein 750 |
