fluvastatin-3032 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

198 genes differentially expressed following the fluvastatin-3032 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTN2 actinin, alpha 2
AGMAT agmatine ureohydrolase (agmatinase)
AMACR alpha-methylacyl-CoA racemase
AP4S1 adaptor-related protein complex 4, sigma 1 subunit
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
ARID4B AT rich interactive domain 4B (RBP1-like)
CACNB2 calcium channel, voltage-dependent, beta 2 subunit
CALD1 caldesmon 1
CAV2 caveolin 2
CCDC92 coiled-coil domain containing 92
CD59 CD59 molecule, complement regulatory protein
CD6 CD6 molecule
CEMP1 cementum protein 1
COL10A1 collagen, type X, alpha 1
CTTN cortactin
CYFIP2 cytoplasmic FMR1 interacting protein 2
DCT dopachrome tautomerase
DMD dystrophin
DNASE2 deoxyribonuclease II, lysosomal
EHD2 EH-domain containing 2
EPX eosinophil peroxidase
EPYC epiphycan
EYA3 EYA transcriptional coactivator and phosphatase 3
FER1L4 fer-1-like family member 4, pseudogene (functional)
GABARAPL1 GABA(A) receptor-associated protein like 1
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1
GAS2L1 growth arrest-specific 2 like 1
GATA6 GATA binding protein 6
GHRHR growth hormone releasing hormone receptor
GPC1 glypican 1
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like)
GRIA3 glutamate receptor, ionotropic, AMPA 3
GZMM granzyme M (lymphocyte met-ase 1)
HLA-F major histocompatibility complex, class I, F
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
IL2RA interleukin 2 receptor, alpha
INE1 inactivation escape 1 (non-protein coding)
INF2 inverted formin, FH2 and WH2 domain containing
KIR2DL2 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2
KLF2 Kruppel-like factor 2
KLHL22 kelch-like family member 22
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LAMA2 laminin, alpha 2
LEFTY1 left-right determination factor 1
LZTS1 leucine zipper, putative tumor suppressor 1
MAPK7 mitogen-activated protein kinase 7
MEOX2 mesenchyme homeobox 2
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MX1 MX dynamin-like GTPase 1
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
MYH14 myosin, heavy chain 14, non-muscle
MYL10 myosin, light chain 10, regulatory
MYRF myelin regulatory factor
NDOR1 NADPH dependent diflavin oxidoreductase 1
NR1I2 nuclear receptor subfamily 1, group I, member 2
NR2F2 nuclear receptor subfamily 2, group F, member 2
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OMG oligodendrocyte myelin glycoprotein
OPCML opioid binding protein/cell adhesion molecule-like
PLEK2 pleckstrin 2
PSG1 pregnancy specific beta-1-glycoprotein 1
PTMS parathymosin
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
PYGB phosphorylase, glycogen; brain
RARA retinoic acid receptor, alpha
RASSF9 Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
RBPMS RNA binding protein with multiple splicing
RERE arginine-glutamic acid dipeptide (RE) repeats
RFC1 replication factor C (activator 1) 1, 145kDa
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
RPL10 ribosomal protein L10
SCIN scinderin
SEZ6L seizure related 6 homolog (mouse)-like
SFRP5 secreted frizzled-related protein 5
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SIGLEC9 sialic acid binding Ig-like lectin 9
SIX3 SIX homeobox 3
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SNPH syntaphilin
SOCS6 suppressor of cytokine signaling 6
SORBS2 sorbin and SH3 domain containing 2
SPARCL1 SPARC-like 1 (hevin)
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
SPTBN5 spectrin, beta, non-erythrocytic 5
SRPK3 SRSF protein kinase 3
ST7L suppression of tumorigenicity 7 like
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
TCEAL2 transcription elongation factor A (SII)-like 2
TLX3 T-cell leukemia homeobox 3
TNC tenascin C
TRIM10 tripartite motif containing 10
TSKU tsukushi, small leucine rich proteoglycan
TSR3 TSR3, 20S rRNA accumulation, homolog (S. cerevisiae)
TTN titin
USP29 ubiquitin specific peptidase 29
YIPF2 Yip1 domain family, member 2
ZFHX3 zinc finger homeobox 3
ZNF287 zinc finger protein 287
ZNF407 zinc finger protein 407

decreased expression

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ACPP acid phosphatase, prostate
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADTRP androgen-dependent TFPI-regulating protein
AEN apoptosis enhancing nuclease
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
ARMC6 armadillo repeat containing 6
ARMCX4 armadillo repeat containing, X-linked 4
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BSPRY B-box and SPRY domain containing
BTF3P11 basic transcription factor 3 pseudogene 11
BTF3P12 basic transcription factor 3 pseudogene 12
C16ORF59 chromosome 16 open reading frame 59
C1ORF56 chromosome 1 open reading frame 56
C5AR1 complement component 5a receptor 1
CCRL2 chemokine (C-C motif) receptor-like 2
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase)
CDR2L cerebellar degeneration-related protein 2-like
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
COL15A1 collagen, type XV, alpha 1
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CTAGE9 CTAGE family, member 9
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DPYS dihydropyrimidinase
DTX2 deltex 2, E3 ubiquitin ligase
DUSP2 dual specificity phosphatase 2
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EGR1 early growth response 1
EHD3 EH-domain containing 3
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FER fer (fps/fes related) tyrosine kinase
FOSL1 FOS-like antigen 1
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GJA1 gap junction protein, alpha 1, 43kDa
GMPPB GDP-mannose pyrophosphorylase B
GPR1 G protein-coupled receptor 1
GPR68 G protein-coupled receptor 68
HIST1H3B histone cluster 1, H3b
IBSP integrin-binding sialoprotein
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KDM7A lysine (K)-specific demethylase 7A
KIAA0319L KIAA0319-like
KLHL36 kelch-like family member 36
KRT81 keratin 81, type II
LTB lymphotoxin beta (TNF superfamily, member 3)
MAGEH1 melanoma antigen family H1
MBNL3 muscleblind-like splicing regulator 3
MFSD11 major facilitator superfamily domain containing 11
MUL1 mitochondrial E3 ubiquitin protein ligase 1
N6AMT1 N-6 adenine-specific DNA methyltransferase 1 (putative)
NAT6 N-acetyltransferase 6 (GCN5-related)
NEK11 NIMA-related kinase 11
NINJ2 ninjurin 2
NOTCH1 notch 1
PBOV1 prostate and breast cancer overexpressed 1
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PDZD7 PDZ domain containing 7
PHACTR1 phosphatase and actin regulator 1
PMFBP1 polyamine modulated factor 1 binding protein 1
POM121 POM121 transmembrane nucleoporin
POMZP3 POM121 and ZP3 fusion
PROCR protein C receptor, endothelial
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RCAN3 RCAN family member 3
RPL13P5 ribosomal protein L13 pseudogene 5
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
RUSC2 RUN and SH3 domain containing 2
SAV1 salvador family WW domain containing protein 1
SLC16A4 solute carrier family 16, member 4
SLC17A2 solute carrier family 17, member 2
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC35F5 solute carrier family 35, member F5
SLC35F6 solute carrier family 35, member F6
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SPATA2L spermatogenesis associated 2-like
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TBC1D17 TBC1 domain family, member 17
TMEM209 transmembrane protein 209
TNF tumor necrosis factor
TNNT1 troponin T type 1 (skeletal, slow)
TONSL tonsoku-like, DNA repair protein
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae)
TRPS1 trichorhinophalangeal syndrome I
TTLL1 tubulin tyrosine ligase-like family member 1
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1
USP32 ubiquitin specific peptidase 32
XPC xeroderma pigmentosum, complementation group C
ZKSCAN8 zinc finger with KRAB and SCAN domains 8
ZNF225 zinc finger protein 225
ZNF480 zinc finger protein 480
ZNF696 zinc finger protein 696
ZNF8 zinc finger protein 8