| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
196 genes differentially expressed following the fluvastatin-5290 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ALDH3B2 | aldehyde dehydrogenase 3 family, member B2 |
| APP | amyloid beta (A4) precursor protein |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| ATF7IP | activating transcription factor 7 interacting protein |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 |
| AXIN1 | axin 1 |
| BLVRA | biliverdin reductase A |
| BMP1 | bone morphogenetic protein 1 |
| BTBD2 | BTB (POZ) domain containing 2 |
| C5 | complement component 5 |
| CDC25C | cell division cycle 25C |
| CLEC11A | C-type lectin domain family 11, member A |
| CORT | cortistatin |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like |
| CUL9 | cullin 9 |
| CYLD | cylindromatosis (turban tumor syndrome) |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DTX4 | deltex 4, E3 ubiquitin ligase |
| EHMT2 | euchromatic histone-lysine N-methyltransferase 2 |
| EML3 | echinoderm microtubule associated protein like 3 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| F2R | coagulation factor II (thrombin) receptor |
| FLJ11292 | |
| GCHFR | GTP cyclohydrolase I feedback regulator |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) |
| GPATCH4 | G patch domain containing 4 |
| GPRC5C | G protein-coupled receptor, class C, group 5, member C |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase |
| HOMER3 | homer scaffolding protein 3 |
| HPS1 | Hermansky-Pudlak syndrome 1 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFITM1 | interferon induced transmembrane protein 1 |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| IPO9 | importin 9 |
| IRF2 | interferon regulatory factor 2 |
| JRK | Jrk homolog (mouse) |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KCNG1 | potassium channel, voltage gated modifier subfamily G, member 1 |
| KHNYN | KH and NYN domain containing |
| KIFAP3 | kinesin-associated protein 3 |
| KLF2 | Kruppel-like factor 2 |
| KLF6 | Kruppel-like factor 6 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) |
| KRT31 | keratin 31, type I |
| LDLR | low density lipoprotein receptor |
| LPIN1 | lipin 1 |
| MAP4 | microtubule-associated protein 4 |
| MATK | megakaryocyte-associated tyrosine kinase |
| MCF2L | MCF.2 cell line derived transforming sequence-like |
| MVD | mevalonate (diphospho) decarboxylase |
| MXD3 | MAX dimerization protein 3 |
| N4BP1 | NEDD4 binding protein 1 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) |
| NAB2 | NGFI-A binding protein 2 (EGR1 binding protein 2) |
| NDRG3 | NDRG family member 3 |
| NNT | nicotinamide nucleotide transhydrogenase |
| NOL12 | nucleolar protein 12 |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| OGFOD2 | 2-oxoglutarate and iron-dependent oxygenase domain containing 2 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PDGFA | platelet-derived growth factor alpha polypeptide |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PLK4 | polo-like kinase 4 |
| PRKCH | protein kinase C, eta |
| PXN | paxillin |
| RABGAP1 | RAB GTPase activating protein 1 |
| RHOB | ras homolog family member B |
| RNF19B | ring finger protein 19B |
| RNF41 | ring finger protein 41, E3 ubiquitin protein ligase |
| RPGR | retinitis pigmentosa GTPase regulator |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) |
| RRP7A | ribosomal RNA processing 7 homolog A (S. cerevisiae) |
| RUFY3 | RUN and FYVE domain containing 3 |
| RYR2 | ryanodine receptor 2 (cardiac) |
| SENP6 | SUMO1/sentrin specific peptidase 6 |
| SIRT3 | sirtuin 3 |
| SIRT6 | sirtuin 6 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SP110 | SP110 nuclear body protein |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 |
| SQLE | squalene epoxidase |
| SRCAP | Snf2-related CREBBP activator protein |
| STC1 | stanniocalcin 1 |
| TAOK1 | TAO kinase 1 |
| TAOK2 | TAO kinase 2 |
| TBC1D17 | TBC1 domain family, member 17 |
| TBX19 | T-box 19 |
| TEAD3 | TEA domain family member 3 |
| UBXN1 | UBX domain protein 1 |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| ZBTB1 | zinc finger and BTB domain containing 1 |
| ZSCAN26 | zinc finger and SCAN domain containing 26 |
| Symbol | Name |
|---|---|
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| ADAM15 | ADAM metallopeptidase domain 15 |
| ADORA2B | adenosine A2b receptor |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| APOD | apolipoprotein D |
| ARMC6 | armadillo repeat containing 6 |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) |
| ATXN2 | ataxin 2 |
| BAHD1 | bromo adjacent homology domain containing 1 |
| BAX | BCL2-associated X protein |
| BDH2 | 3-hydroxybutyrate dehydrogenase, type 2 |
| BPGM | 2,3-bisphosphoglycerate mutase |
| C4ORF19 | chromosome 4 open reading frame 19 |
| CCDC94 | coiled-coil domain containing 94 |
| CD302 | CD302 molecule |
| CHST7 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DNAAF2 | dynein, axonemal, assembly factor 2 |
| ERCC6L | excision repair cross-complementation group 6-like |
| FAIM | Fas apoptotic inhibitory molecule |
| FAM169A | family with sequence similarity 169, member A |
| FAM86C1 | family with sequence similarity 86, member C1 |
| FKBPL | FK506 binding protein like |
| GLI3 | GLI family zinc finger 3 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HIRA | histone cell cycle regulator |
| HIST1H1D | histone cluster 1, H1d |
| HMGB3P1 | high mobility group box 3 pseudogene 1 |
| HMOX1 | heme oxygenase 1 |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| KIAA0232 | KIAA0232 |
| KIFC1 | kinesin family member C1 |
| LAMB2 | laminin, beta 2 (laminin S) |
| LMNB1 | lamin B1 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 |
| MBTD1 | mbt domain containing 1 |
| MEIS2 | Meis homeobox 2 |
| MUM1 | melanoma associated antigen (mutated) 1 |
| MYO19 | myosin XIX |
| NAT9 | N-acetyltransferase 9 (GCN5-related, putative) |
| NDST2 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| NT5C | 5', 3'-nucleotidase, cytosolic |
| NUPL2 | nucleoporin like 2 |
| OLFML3 | olfactomedin-like 3 |
| PGP | phosphoglycolate phosphatase |
| PIBF1 | progesterone immunomodulatory binding factor 1 |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 |
| PMCH | pro-melanin-concentrating hormone |
| PP14571 | uncharacterized LOC100130449 |
| PRAF2 | PRA1 domain family, member 2 |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PROS1 | protein S (alpha) |
| PSTPIP2 | proline-serine-threonine phosphatase interacting protein 2 |
| RABL6 | RAB, member RAS oncogene family-like 6 |
| RBL1 | retinoblastoma-like 1 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 |
| RSF1 | remodeling and spacing factor 1 |
| SCAI | suppressor of cancer cell invasion |
| SCD5 | stearoyl-CoA desaturase 5 |
| SDF2 | stromal cell-derived factor 2 |
| SHARPIN | SHANK-associated RH domain interactor |
| SIK1 | salt-inducible kinase 1 |
| SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SND1-IT1 | SND1 intronic transcript 1 |
| STAG3 | stromal antigen 3 |
| SYTL2 | synaptotagmin-like 2 |
| TAF5L | TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TLN1 | talin 1 |
| TMC5 | transmembrane channel-like 5 |
| TNK1 | tyrosine kinase, non-receptor, 1 |
| TRIM5 | tripartite motif containing 5 |
| TUBA3C | tubulin, alpha 3c |
| UBE2O | ubiquitin-conjugating enzyme E2O |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZBTB25 | zinc finger and BTB domain containing 25 |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZDHHC11 | zinc finger, DHHC-type containing 11 |
| ZNF141 | zinc finger protein 141 |
| ZNF268 | zinc finger protein 268 |
| ZNF451 | zinc finger protein 451 |
| ZNF586 | zinc finger protein 586 |
| ZNF639 | zinc finger protein 639 |
| ZNF652 | zinc finger protein 652 |
| ZNF668 | zinc finger protein 668 |
