| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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197 genes differentially expressed following the fluvoxamine-2913 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC6 | ATP-binding cassette, sub-family C (CFTR/MRP), member 6 |
| ADTRP | androgen-dependent TFPI-regulating protein |
| ANO2 | anoctamin 2, calcium activated chloride channel |
| AP3S2 | adaptor-related protein complex 3, sigma 2 subunit |
| ARHGAP44 | Rho GTPase activating protein 44 |
| ASIC4 | acid sensing (proton gated) ion channel family member 4 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 |
| ATP6V0A2 | ATPase, H+ transporting, lysosomal V0 subunit a2 |
| BCL2L10 | BCL2-like 10 (apoptosis facilitator) |
| BLZF1 | basic leucine zipper nuclear factor 1 |
| C5AR2 | complement component 5a receptor 2 |
| C7ORF69 | chromosome 7 open reading frame 69 |
| CC2D1A | coiled-coil and C2 domain containing 1A |
| CD59 | CD59 molecule, complement regulatory protein |
| CECR1 | cat eye syndrome chromosome region, candidate 1 |
| CEP41 | centrosomal protein 41kDa |
| CHI3L2 | chitinase 3-like 2 |
| CLGN | calmegin |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 |
| COL8A2 | collagen, type VIII, alpha 2 |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CRAT | carnitine O-acetyltransferase |
| CREBBP | CREB binding protein |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 |
| CXCR3 | chemokine (C-X-C motif) receptor 3 |
| DMWD | dystrophia myotonica, WD repeat containing |
| DRD2 | dopamine receptor D2 |
| EMILIN2 | elastin microfibril interfacer 2 |
| ETV7 | ets variant 7 |
| EXO5 | exonuclease 5 |
| F2R | coagulation factor II (thrombin) receptor |
| FAM3A | family with sequence similarity 3, member A |
| FAM86C1 | family with sequence similarity 86, member C1 |
| FOSL2 | FOS-like antigen 2 |
| FSTL1 | follistatin-like 1 |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| GTDC1 | glycosyltransferase-like domain containing 1 |
| HRASLS2 | HRAS-like suppressor 2 |
| IFNW1 | interferon, omega 1 |
| IGLL3P | immunoglobulin lambda-like polypeptide 3, pseudogene |
| IL5 | interleukin 5 |
| INA | internexin neuronal intermediate filament protein, alpha |
| ITPK1 | inositol-tetrakisphosphate 1-kinase |
| JAK3 | Janus kinase 3 |
| JUND | jun D proto-oncogene |
| KCNMB4 | potassium channel subfamily M regulatory beta subunit 4 |
| KHSRP | KH-type splicing regulatory protein |
| KIR2DL1 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 |
| KLF5 | Kruppel-like factor 5 (intestinal) |
| LAMC2 | laminin, gamma 2 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LMNA | lamin A/C |
| MAPT | microtubule-associated protein tau |
| MASP2 | mannan-binding lectin serine peptidase 2 |
| MLLT4 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 |
| MLXIP | MLX interacting protein |
| MTL5 | metallothionein-like 5, testis-specific (tesmin) |
| MTOR | mechanistic target of rapamycin (serine/threonine kinase) |
| MYL10 | myosin, light chain 10, regulatory |
| NOS1 | nitric oxide synthase 1 (neuronal) |
| NPFFR1 | neuropeptide FF receptor 1 |
| NUP88 | nucleoporin 88kDa |
| NXPH3 | neurexophilin 3 |
| OPTN | optineurin |
| OTUB1 | OTU deubiquitinase, ubiquitin aldehyde binding 1 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 |
| PCDHGA8 | protocadherin gamma subfamily A, 8 |
| PDE2A | phosphodiesterase 2A, cGMP-stimulated |
| PEG10 | paternally expressed 10 |
| PEX3 | peroxisomal biogenesis factor 3 |
| PIAS2 | protein inhibitor of activated STAT, 2 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) |
| POU5F1P4 | POU class 5 homeobox 1 pseudogene 4 |
| POU6F1 | POU class 6 homeobox 1 |
| PRO2964 | uncharacterized protein PRO2964 |
| RAB6A | RAB6A, member RAS oncogene family |
| SAMD4A | sterile alpha motif domain containing 4A |
| SDHB | succinate dehydrogenase complex, subunit B, iron sulfur (Ip) |
| SEC61A2 | Sec61 alpha 2 subunit (S. cerevisiae) |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) |
| SFTPC | surfactant protein C |
| SIGLEC7 | sialic acid binding Ig-like lectin 7 |
| SLC6A13 | solute carrier family 6 (neurotransmitter transporter), member 13 |
| SORBS3 | sorbin and SH3 domain containing 3 |
| SRCAP | Snf2-related CREBBP activator protein |
| SSX1 | synovial sarcoma, X breakpoint 1 |
| ST7L | suppression of tumorigenicity 7 like |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 |
| TBX5 | T-box 5 |
| THAP3 | THAP domain containing, apoptosis associated protein 3 |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
| TYMP | thymidine phosphorylase |
| UBTF | upstream binding transcription factor, RNA polymerase I |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) |
| WDTC1 | WD and tetratricopeptide repeats 1 |
| ZNF177 | zinc finger protein 177 |
| ZNF862 | zinc finger protein 862 |
| Symbol | Name |
|---|---|
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| APOBR | apolipoprotein B receptor |
| ARAP3 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 |
| ARHGAP12 | Rho GTPase activating protein 12 |
| ASGR2 | asialoglycoprotein receptor 2 |
| ATP6V0E2 | ATPase, H+ transporting V0 subunit e2 |
| BATF | basic leucine zipper transcription factor, ATF-like |
| BBS7 | Bardet-Biedl syndrome 7 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase |
| BSCL2 | Berardinelli-Seip congenital lipodystrophy 2 (seipin) |
| CBX4 | chromobox homolog 4 |
| CCNT1 | cyclin T1 |
| CD300C | CD300c molecule |
| CHM | choroideremia (Rab escort protein 1) |
| CPSF7 | cleavage and polyadenylation specific factor 7, 59kDa |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CYP20A1 | cytochrome P450, family 20, subfamily A, polypeptide 1 |
| CYP2R1 | cytochrome P450, family 2, subfamily R, polypeptide 1 |
| DCAF17 | DDB1 and CUL4 associated factor 17 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DGKZ | diacylglycerol kinase, zeta |
| DNAAF2 | dynein, axonemal, assembly factor 2 |
| DOLK | dolichol kinase |
| ECM1 | extracellular matrix protein 1 |
| ECSIT | ECSIT signalling integrator |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| FAM86B1 | family with sequence similarity 86, member B1 |
| FBRS | fibrosin |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| GK3P | glycerol kinase 3 pseudogene |
| GRAMD1B | GRAM domain containing 1B |
| GRINA | glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) |
| HIRA | histone cell cycle regulator |
| HIST1H2BC | histone cluster 1, H2bc |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 |
| KIF24 | kinesin family member 24 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 |
| LRRC37A2 | leucine rich repeat containing 37, member A2 |
| LTB4R | leukotriene B4 receptor |
| MANSC1 | MANSC domain containing 1 |
| MAP4K2 | mitogen-activated protein kinase kinase kinase kinase 2 |
| MATK | megakaryocyte-associated tyrosine kinase |
| MED15 | mediator complex subunit 15 |
| METTL16 | methyltransferase like 16 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs |
| MLYCD | malonyl-CoA decarboxylase |
| MRGBP | MRG/MORF4L binding protein |
| MTERF4 | mitochondrial transcription termination factor 4 |
| MXD3 | MAX dimerization protein 3 |
| N4BP2L2-IT2 | N4BPL2 intronic transcript 2 |
| NDUFAF7 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 |
| NEIL3 | nei endonuclease VIII-like 3 (E. coli) |
| NME6 | NME/NM23 nucleoside diphosphate kinase 6 |
| NUBPL | nucleotide binding protein-like |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PARPBP | PARP1 binding protein |
| PBLD | phenazine biosynthesis-like protein domain containing |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
| PTH2R | parathyroid hormone 2 receptor |
| RBM41 | RNA binding motif protein 41 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RHOH | ras homolog family member H |
| RPA4 | replication protein A4, 30kDa |
| SARS2 | seryl-tRNA synthetase 2, mitochondrial |
| SEC31B | SEC31 homolog B (S. cerevisiae) |
| SEMA3G | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G |
| SERGEF | secretion regulating guanine nucleotide exchange factor |
| SHPK | sedoheptulokinase |
| SKI | SKI proto-oncogene |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC15A3 | solute carrier family 15 (oligopeptide transporter), member 3 |
| SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 |
| SLFN12 | schlafen family member 12 |
| SLITRK5 | SLIT and NTRK-like family, member 5 |
| SMA4 | glucuronidase, beta pseudogene |
| SNHG20 | small nucleolar RNA host gene 20 |
| SPAG4 | sperm associated antigen 4 |
| SPRYD7 | SPRY domain containing 7 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) |
| TGM5 | transglutaminase 5 |
| THAP10 | THAP domain containing 10 |
| TIMM10B | translocase of inner mitochondrial membrane 10 homolog B (yeast) |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) |
| TLN1 | talin 1 |
| TMEM134 | transmembrane protein 134 |
| TMEM254 | transmembrane protein 254 |
| TRABD | TraB domain containing |
| TRDMT1 | tRNA aspartic acid methyltransferase 1 |
| TRPV2 | transient receptor potential cation channel, subfamily V, member 2 |
| UPP1 | uridine phosphorylase 1 |
| URM1 | ubiquitin related modifier 1 |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZMAT3 | zinc finger, matrin-type 3 |
| ZNF12 | zinc finger protein 12 |
| ZNF225 | zinc finger protein 225 |
| ZNF493 | zinc finger protein 493 |