| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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188 genes differentially expressed following the fluvoxamine-3995 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACO2 | aconitase 2, mitochondrial |
| ADRA1D | adrenoceptor alpha 1D |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 |
| APBA1 | amyloid beta (A4) precursor protein-binding, family A, member 1 |
| APOLD1 | apolipoprotein L domain containing 1 |
| APPBP2 | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 |
| ARG1 | arginase 1 |
| BGN | biglycan |
| BMP4 | bone morphogenetic protein 4 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| C16ORF70 | chromosome 16 open reading frame 70 |
| C1ORF54 | chromosome 1 open reading frame 54 |
| C8A | complement component 8, alpha polypeptide |
| CCL2 | chemokine (C-C motif) ligand 2 |
| CCL27 | chemokine (C-C motif) ligand 27 |
| CD4 | CD4 molecule |
| CFAP70 | cilia and flagella associated protein 70 |
| CLCA2 | chloride channel accessory 2 |
| CST1 | cystatin SN |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 |
| DPF3 | D4, zinc and double PHD fingers, family 3 |
| ETV1 | ets variant 1 |
| FCGR2A | Fc fragment of IgG, low affinity IIa, receptor (CD32) |
| FGFR4 | fibroblast growth factor receptor 4 |
| FZD9 | frizzled class receptor 9 |
| GDF5 | growth differentiation factor 5 |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O |
| GRIA3 | glutamate receptor, ionotropic, AMPA 3 |
| HABP4 | hyaluronan binding protein 4 |
| HBB | hemoglobin, beta |
| HCFC1 | host cell factor C1 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HOXA6 | homeobox A6 |
| HOXD11 | homeobox D11 |
| HOXD13 | homeobox D13 |
| HR | hair growth associated |
| HS6ST1 | heparan sulfate 6-O-sulfotransferase 1 |
| IDS | iduronate 2-sulfatase |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
| IL32 | interleukin 32 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 |
| JUND | jun D proto-oncogene |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 |
| KHK | ketohexokinase (fructokinase) |
| KIR2DL3 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 |
| KLK7 | kallikrein-related peptidase 7 |
| LAMB4 | laminin, beta 4 |
| LCP2 | lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) |
| LOXL2 | lysyl oxidase-like 2 |
| LTBP4 | latent transforming growth factor beta binding protein 4 |
| MTMR1 | myotubularin related protein 1 |
| MYCL | v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog |
| MYH11 | myosin, heavy chain 11, smooth muscle |
| NNMT | nicotinamide N-methyltransferase |
| NPPB | natriuretic peptide B |
| NPTX1 | neuronal pentraxin I |
| NRG1 | neuregulin 1 |
| PART1 | prostate androgen-regulated transcript 1 (non-protein coding) |
| PLAC4 | placenta-specific 4 |
| PLCL2 | phospholipase C-like 2 |
| PLXDC1 | plexin domain containing 1 |
| PON1 | paraoxonase 1 |
| POU5F1P3 | POU class 5 homeobox 1 pseudogene 3 |
| PP14571 | uncharacterized LOC100130449 |
| PPP2R2B | protein phosphatase 2, regulatory subunit B, beta |
| RDH8 | retinol dehydrogenase 8 (all-trans) |
| RGS6 | regulator of G-protein signaling 6 |
| RPL35A | ribosomal protein L35a |
| RRAD | Ras-related associated with diabetes |
| RUNX1 | runt-related transcription factor 1 |
| SCAND2P | SCAN domain containing 2 pseudogene |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SIX3 | SIX homeobox 3 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SOX15 | SRY (sex determining region Y)-box 15 |
| SPANXC | SPANX family, member C |
| SPON1 | spondin 1, extracellular matrix protein |
| SRCAP | Snf2-related CREBBP activator protein |
| STRN | striatin, calmodulin binding protein |
| SV2B | synaptic vesicle glycoprotein 2B |
| TADA2A | transcriptional adaptor 2A |
| TAS2R1 | taste receptor, type 2, member 1 |
| THBD | thrombomodulin |
| TJP3 | tight junction protein 3 |
| TLE2 | transducin-like enhancer of split 2 |
| TRIM66 | tripartite motif containing 66 |
| TRPC4 | transient receptor potential cation channel, subfamily C, member 4 |
| VIPR2 | vasoactive intestinal peptide receptor 2 |
| VSNL1 | visinin-like 1 |
| ZNF224 | zinc finger protein 224 |
| ZNF334 | zinc finger protein 334 |
| ZNF75D | zinc finger protein 75D |
| Symbol | Name |
|---|---|
| ABCA11P | ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene |
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| ADGRF1 | adhesion G protein-coupled receptor F1 |
| AGO4 | argonaute RISC catalytic component 4 |
| ARHGAP10 | Rho GTPase activating protein 10 |
| ARHGAP24 | Rho GTPase activating protein 24 |
| ARID3A | AT rich interactive domain 3A (BRIGHT-like) |
| ASTE1 | asteroid homolog 1 (Drosophila) |
| ATAD3A | ATPase family, AAA domain containing 3A |
| ATAD5 | ATPase family, AAA domain containing 5 |
| AXIN1 | axin 1 |
| BATF3 | basic leucine zipper transcription factor, ATF-like 3 |
| BHLHB9 | basic helix-loop-helix domain containing, class B, 9 |
| CA9 | carbonic anhydrase IX |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| CRYBA2 | crystallin, beta A2 |
| CTSF | cathepsin F |
| DBF4B | DBF4 zinc finger B |
| DDN | dendrin |
| DENND4A | DENN/MADD domain containing 4A |
| EFNA3 | ephrin-A3 |
| EN2 | engrailed homeobox 2 |
| ENDOG | endonuclease G |
| EPN3 | epsin 3 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| GHR | growth hormone receptor |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 |
| GPR1 | G protein-coupled receptor 1 |
| GPX2 | glutathione peroxidase 2 |
| GTF2I | general transcription factor IIi |
| HIST1H1E | histone cluster 1, H1e |
| HIST1H2AJ | histone cluster 1, H2aj |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| HSPA1L | heat shock 70kDa protein 1-like |
| IFT54 | intraflagellar transport 54 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KIAA1107 | KIAA1107 |
| KIAA1549L | KIAA1549-like |
| KIRREL | kin of IRRE like (Drosophila) |
| LMTK1 | lemur tail kinase 1 |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LYPD1 | LY6/PLAUR domain containing 1 |
| MAGEA6 | melanoma antigen family A6 |
| MAP4K2 | mitogen-activated protein kinase kinase kinase kinase 2 |
| MAPK12 | mitogen-activated protein kinase 12 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| ME3 | malic enzyme 3, NADP(+)-dependent, mitochondrial |
| MN1 | meningioma (disrupted in balanced translocation) 1 |
| MOCS3 | molybdenum cofactor synthesis 3 |
| MTSS1L | metastasis suppressor 1-like |
| NDP | Norrie disease (pseudoglioma) |
| NME5 | NME/NM23 family member 5 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NXPE3 | neurexophilin and PC-esterase domain family, member 3 |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| PALMD | palmdelphin |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit |
| PAQR6 | progestin and adipoQ receptor family member VI |
| PCOLCE | procollagen C-endopeptidase enhancer |
| PDE8B | phosphodiesterase 8B |
| PLAG1 | pleiomorphic adenoma gene 1 |
| PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) |
| PLD3 | phospholipase D family, member 3 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| PRMT7 | protein arginine methyltransferase 7 |
| PRR14L | proline rich 14-like |
| PWAR5 | Prader Willi/Angelman region RNA 5 |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| S100A3 | S100 calcium binding protein A3 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SETD6 | SET domain containing 6 |
| SH2D4A | SH2 domain containing 4A |
| STARD3 | StAR-related lipid transfer (START) domain containing 3 |
| TARS2 | threonyl-tRNA synthetase 2, mitochondrial (putative) |
| TGS1 | trimethylguanosine synthase 1 |
| THAP10 | THAP domain containing 10 |
| TMEM209 | transmembrane protein 209 |
| TMEM62 | transmembrane protein 62 |
| TRDMT1 | tRNA aspartic acid methyltransferase 1 |
| TRIM9 | tripartite motif containing 9 |
| TXLNG | taxilin gamma |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZNF239 | zinc finger protein 239 |
| ZNF268 | zinc finger protein 268 |
| ZNF528 | zinc finger protein 528 |
| ZNF606 | zinc finger protein 606 |
| ZNF85 | zinc finger protein 85 |
| ZNHIT2 | zinc finger, HIT-type containing 2 |