fluvoxamine-4114 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the fluvoxamine-4114 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACPP acid phosphatase, prostate
ADGB androglobin
ADRA1A adrenoceptor alpha 1A
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALDOB aldolase B, fructose-bisphosphate
ANG angiogenin, ribonuclease, RNase A family, 5
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATN1 atrophin 1
ATXN2L ataxin 2-like
BAIAP3 BAI1-associated protein 3
BIRC3 baculoviral IAP repeat containing 3
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CCDC181 coiled-coil domain containing 181
CCNG2 cyclin G2
CD52 CD52 molecule
CD58 CD58 molecule
CDK13 cyclin-dependent kinase 13
CDKN2A cyclin-dependent kinase inhibitor 2A
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLCN6 chloride channel, voltage-sensitive 6
COL5A2 collagen, type V, alpha 2
CPQ carboxypeptidase Q
CRISP2 cysteine-rich secretory protein 2
CTIF CBP80/20-dependent translation initiation factor
CTSE cathepsin E
CYP4F8 cytochrome P450, family 4, subfamily F, polypeptide 8
DAO D-amino-acid oxidase
DFNB31 deafness, autosomal recessive 31
DIAPH2-AS1 DIAPH2 antisense RNA 1
DMP1 dentin matrix acidic phosphoprotein 1
DTX2 deltex 2, E3 ubiquitin ligase
DUSP6 dual specificity phosphatase 6
EGR1 early growth response 1
ELAVL2 ELAV like neuron-specific RNA binding protein 2
ELL2 elongation factor, RNA polymerase II, 2
EPHB2 EPH receptor B2
FCAR Fc fragment of IgA receptor
FLOT1 flotillin 1
FSCN3 fascin actin-bundling protein 3, testicular
GAB1 GRB2-associated binding protein 1
GDPD2 glycerophosphodiester phosphodiesterase domain containing 2
GPR183 G protein-coupled receptor 183
HDAC5 histone deacetylase 5
HNF1B HNF1 homeobox B
HOXA10 homeobox A10
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
ICA1 islet cell autoantigen 1, 69kDa
INSIG1 insulin induced gene 1
IRS2 insulin receptor substrate 2
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
LAPTM5 lysosomal protein transmembrane 5
LOC399491
LPIN1 lipin 1
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MALL mal, T-cell differentiation protein-like
MAPK14 mitogen-activated protein kinase 14
MEF2D myocyte enhancer factor 2D
MEFV Mediterranean fever
MID1 midline 1
MOB3B MOB kinase activator 3B
MOBP myelin-associated oligodendrocyte basic protein
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MXD4 MAX dimerization protein 4
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NF2 neurofibromin 2 (merlin)
NPTXR neuronal pentraxin receptor
NR6A1 nuclear receptor subfamily 6, group A, member 1
NRP1 neuropilin 1
OPCML opioid binding protein/cell adhesion molecule-like
PALM paralemmin
PLAG1 pleiomorphic adenoma gene 1
PLK3 polo-like kinase 3
PML promyelocytic leukemia
RAB2A RAB2A, member RAS oncogene family
SATB2 SATB homeobox 2
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
SIX3 SIX homeobox 3
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC25A30 solute carrier family 25, member 30
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC6A16 solute carrier family 6, member 16
SLCO4C1 solute carrier organic anion transporter family, member 4C1
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SPINK1 serine peptidase inhibitor, Kazal type 1
STS steroid sulfatase (microsomal), isozyme S
SUGP1 SURP and G patch domain containing 1
SULT4A1 sulfotransferase family 4A, member 1
TEX14 testis expressed 14
TFEB transcription factor EB
THRB thyroid hormone receptor, beta
TIMP3 TIMP metallopeptidase inhibitor 3
TNC tenascin C
TSC22D4 TSC22 domain family, member 4
UHRF1BP1L UHRF1 binding protein 1-like
ZIC3 Zic family member 3
ZNF415 zinc finger protein 415

decreased expression

Symbol Name
ACTL8 actin-like 8
ALS2CL ALS2 C-terminal like
AP1AR adaptor-related protein complex 1 associated regulatory protein
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BMP15 bone morphogenetic protein 15
C17ORF70 chromosome 17 open reading frame 70
C19ORF40 chromosome 19 open reading frame 40
C19ORF73 chromosome 19 open reading frame 73
C22ORF29 chromosome 22 open reading frame 29
C7ORF43 chromosome 7 open reading frame 43
C9ORF9 chromosome 9 open reading frame 9
CA5BP1 carbonic anhydrase VB pseudogene 1
CCDC15 coiled-coil domain containing 15
CD3D CD3d molecule, delta (CD3-TCR complex)
CD82 CD82 molecule
CEL carboxyl ester lipase
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
DCAF13 DDB1 and CUL4 associated factor 13
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
ELP6 elongator acetyltransferase complex subunit 6
EN2 engrailed homeobox 2
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM169A family with sequence similarity 169, member A
FSTL3 follistatin-like 3 (secreted glycoprotein)
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GAMT guanidinoacetate N-methyltransferase
GATA4 GATA binding protein 4
GDAP1 ganglioside induced differentiation associated protein 1
GNG13 guanine nucleotide binding protein (G protein), gamma 13
GPC4 glypican 4
GPR19 G protein-coupled receptor 19
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H1E histone cluster 1, H1e
HIST1H2AJ histone cluster 1, H2aj
HIST1H2AK histone cluster 1, H2ak
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HOXC5 homeobox C5
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IFI6 interferon, alpha-inducible protein 6
IL22 interleukin 22
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIAA0020 KIAA0020
LAX1 lymphocyte transmembrane adaptor 1
LRRC49 leucine rich repeat containing 49
MAGEH1 melanoma antigen family H1
MED15 mediator complex subunit 15
MFAP2 microfibrillar-associated protein 2
MMP3 matrix metallopeptidase 3
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NPFFR1 neuropeptide FF receptor 1
PARP12 poly (ADP-ribose) polymerase family, member 12
PCDHGB5 protocadherin gamma subfamily B, 5
PDLIM2 PDZ and LIM domain 2 (mystique)
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PLEKHA6 pleckstrin homology domain containing, family A member 6
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PRR14L proline rich 14-like
PTCD2 pentatricopeptide repeat domain 2
PTPN14 protein tyrosine phosphatase, non-receptor type 14
RAB30 RAB30, member RAS oncogene family
RNF122 ring finger protein 122
RPL13P5 ribosomal protein L13 pseudogene 5
RSRC1 arginine/serine-rich coiled-coil 1
S100A9 S100 calcium binding protein A9
SAMD9 sterile alpha motif domain containing 9
SCRN3 secernin 3
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SMAD5 SMAD family member 5
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SPIN1 spindlin 1
STAG3L4 stromal antigen 3-like 4 (pseudogene)
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
TADA2A transcriptional adaptor 2A
TDRD1 tudor domain containing 1
TESC tescalcin
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TIPRL TOR signaling pathway regulator
TMEM209 transmembrane protein 209
TRAIP TRAF interacting protein
TRIM25 tripartite motif containing 25
TSGA10 testis specific, 10
UBE2W ubiquitin-conjugating enzyme E2W (putative)
UPK2 uroplakin 2
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
URM1 ubiquitin related modifier 1
USP27X ubiquitin specific peptidase 27, X-linked
VWA1 von Willebrand factor A domain containing 1
XAB2 XPA binding protein 2
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF675 zinc finger protein 675
ZNF747 zinc finger protein 747