focal hepatic necrosis Gene Set

Dataset	MPO Gene-Phenotype Associations
Category	disease or phenotype associations
Type	phenotype
Description	morphological changes resulting from one or more localized areas of pathological death of some or all liver tissue; usually due to irreversible damage (Mammalian Phenotype Ontology, MP_0001656)
External Link	http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0001656
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Genes

11 gene mutations causing the focal hepatic necrosis phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol	Name
C3	complement component 3
C5AR2	complement component 5a receptor 2
FAS	Fas cell surface death receptor
FASLG	Fas ligand (TNF superfamily, member 6)
FGA	fibrinogen alpha chain
IGFBP1	insulin-like growth factor binding protein 1
NF1	neurofibromin 1
NR1H4	nuclear receptor subfamily 1, group H, member 4
PROC	protein C (inactivator of coagulation factors Va and VIIIa)
SPTA1	spectrin, alpha, erythrocytic 1
TLR4	toll-like receptor 4