focus Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

203 genes co-occuring with the biological term focus in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCC11 ATP-binding cassette, sub-family C (CFTR/MRP), member 11
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACE2 angiotensin I converting enzyme 2
ACKR3 atypical chemokine receptor 3
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADIPOQ adiponectin, C1Q and collagen domain containing
ADORA2A adenosine A2a receptor
ADORA3 adenosine A3 receptor
AHR aryl hydrocarbon receptor
AHSG alpha-2-HS-glycoprotein
AIP aryl hydrocarbon receptor interacting protein
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALG8 ALG8, alpha-1,3-glucosyltransferase
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
AR androgen receptor
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
ATM ATM serine/threonine kinase
ATMIN ATM interactor
AURKB aurora kinase B
AVPR1A arginine vasopressin receptor 1A
BAK1 BCL2-antagonist/killer 1
BAX BCL2-associated X protein
BCR breakpoint cluster region
BIRC7 baculoviral IAP repeat containing 7
BPIFA4P BPI fold containing family A, member 4, pseudogene
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
CBX4 chromobox homolog 4
CBX8 chromobox homolog 8
CCAR2 cell cycle and apoptosis regulator 2
CCL2 chemokine (C-C motif) ligand 2
CCL5 chemokine (C-C motif) ligand 5
CCNA2 cyclin A2
CCR2 chemokine (C-C motif) receptor 2
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CHD1 chromodomain helicase DNA binding protein 1
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLDN4 claudin 4
CRP C-reactive protein, pentraxin-related
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CTGF connective tissue growth factor
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSB cathepsin B
CTSG cathepsin G
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR2 chemokine (C-X-C motif) receptor 2
CXCR4 chemokine (C-X-C motif) receptor 4
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1)
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
EGFR epidermal growth factor receptor
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
EIF5A2 eukaryotic translation initiation factor 5A2
EPO erythropoietin
ERBB3 erb-b2 receptor tyrosine kinase 3
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
F12 coagulation factor XII (Hageman factor)
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FMN1 formin 1
FMO3 flavin containing monooxygenase 3
FMR1 fragile X mental retardation 1
FN1 fibronectin 1
FOXD1 forkhead box D1
FOXL2 forkhead box L2
FOXM1 forkhead box M1
FOXO1 forkhead box O1
FOXP2 forkhead box P2
FOXP3 forkhead box P3
G6PC3 glucose 6 phosphatase, catalytic, 3
GATA6 GATA binding protein 6
GHRL ghrelin/obestatin prepropeptide
GNA12 guanine nucleotide binding protein (G protein) alpha 12
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GPBAR1 G protein-coupled bile acid receptor 1
GRB14 growth factor receptor-bound protein 14
GRN granulin
H2AFX H2A histone family, member X
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4
HGS hepatocyte growth factor-regulated tyrosine kinase substrate
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-DRB4 major histocompatibility complex, class II, DR beta 4
HLA-G major histocompatibility complex, class I, G
HMOX1 heme oxygenase 1
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HRH1 histamine receptor H1
HRH2 histamine receptor H2
HRH3 histamine receptor H3
HRH4 histamine receptor H4
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
HSPB1 heat shock 27kDa protein 1
IAPP islet amyloid polypeptide
IGFBP6 insulin-like growth factor binding protein 6
IL17A interleukin 17A
IL2RG interleukin 2 receptor, gamma
IL33 interleukin 33
ILK integrin-linked kinase
IPMK inositol polyphosphate multikinase
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
JAK2 Janus kinase 2
KRAS Kirsten rat sarcoma viral oncogene homolog
LEP leptin
LTA lymphotoxin alpha
MAPT microtubule-associated protein tau
MDC1 mediator of DNA-damage checkpoint 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MECOM MDS1 and EVI1 complex locus
MET MET proto-oncogene, receptor tyrosine kinase
MIA melanoma inhibitory activity
MIR206 microRNA 206
MKL1 megakaryoblastic leukemia (translocation) 1
MMP1 matrix metallopeptidase 1
MSH6 mutS homolog 6
MSTN myostatin
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYB v-myb avian myeloblastosis viral oncogene homolog
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
NAMPT nicotinamide phosphoribosyltransferase
NBN nibrin
NEUROD1 neuronal differentiation 1
NF1 neurofibromin 1
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NLRP12 NLR family, pyrin domain containing 12
NLRP6 NLR family, pyrin domain containing 6
NOS1 nitric oxide synthase 1 (neuronal)
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH1 notch 1
NPR2 natriuretic peptide receptor 2
NPY neuropeptide Y
NR0B1 nuclear receptor subfamily 0, group B, member 1
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR5A1 nuclear receptor subfamily 5, group A, member 1
NRG1 neuregulin 1
P2RY12 purinergic receptor P2Y, G-protein coupled, 12
PECAM1 platelet/endothelial cell adhesion molecule 1
PIAS1 protein inhibitor of activated STAT, 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
POLG polymerase (DNA directed), gamma
PPARG peroxisome proliferator-activated receptor gamma
PRC1 protein regulator of cytokinesis 1
PRNP prion protein
PRODH proline dehydrogenase (oxidase) 1
PROS1 protein S (alpha)
PTK2 protein tyrosine kinase 2
PTPN1 protein tyrosine phosphatase, non-receptor type 1
RAD51 RAD51 recombinase
RTN4R reticulon 4 receptor
RUNX1 runt-related transcription factor 1
S100A1 S100 calcium binding protein A1
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SCG5 secretogranin V
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SHH sonic hedgehog
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC45A3 solute carrier family 45, member 3
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOD1 superoxide dismutase 1, soluble
SOD2 superoxide dismutase 2, mitochondrial
SOD3 superoxide dismutase 3, extracellular
TCF7 transcription factor 7 (T-cell specific, HMG-box)
TERC telomerase RNA component
TERT telomerase reverse transcriptase
TGFB1 transforming growth factor, beta 1
TGFBR3 transforming growth factor, beta receptor III
TLR4 toll-like receptor 4
TLR9 toll-like receptor 9
TMPRSS2 transmembrane protease, serine 2
TNF tumor necrosis factor
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TP53 tumor protein p53
TPP2 tripeptidyl peptidase II
TRPM8 transient receptor potential cation channel, subfamily M, member 8
TSC2 tuberous sclerosis 2
TTR transthyretin
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
WWOX WW domain containing oxidoreductase
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta