folic acid metabolic process Gene Set

Dataset	GO Biological Process Annotations 2023
Category	structural or functional annotations
Type	biological process
Description	The chemical reactions and pathways involving folic acid, pteroylglutamic acid. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines. (Gene Ontology, GO_0046655)
External Link	http://amigo.geneontology.org/amigo/term/GO_0046655
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Genes

13 genes participating in the folic acid metabolic process biological process from the curated GO Biological Process Annotations 2023 dataset.

Symbol	Name
DHFR	dihydrofolate reductase
DHFRL1	dihydrofolate reductase-like 1
FPGS	folylpolyglutamate synthase
MTHFD2	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
MTHFD2L	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
MTHFS	5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
MTRR	5-methyltetrahydrofolate-homocysteine methyltransferase reductase
PM20D2	peptidase M20 domain containing 2
SHMT1	serine hydroxymethyltransferase 1 (soluble)
SHMT2	serine hydroxymethyltransferase 2 (mitochondrial)
SLC19A1	solute carrier family 19 (folate transporter), member 1
SLC25A32	solute carrier family 25 (mitochondrial folate carrier), member 32
SLC46A1	solute carrier family 46 (folate transporter), member 1