folic acid-5844 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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199 genes differentially expressed following the folic acid-5844 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD3 abhydrolase domain containing 3
ADAP2 ArfGAP with dual PH domains 2
AKAP7 A kinase (PRKA) anchor protein 7
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
AMT aminomethyltransferase
ARHGAP35 Rho GTPase activating protein 35
ASTN2 astrotactin 2
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
BTG2 BTG family, member 2
C17ORF53 chromosome 17 open reading frame 53
CD6 CD6 molecule
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CES2 carboxylesterase 2
CHAT choline O-acetyltransferase
CHEK2 checkpoint kinase 2
CNOT8 CCR4-NOT transcription complex, subunit 8
COL4A1 collagen, type IV, alpha 1
CPT1A carnitine palmitoyltransferase 1A (liver)
CRLF1 cytokine receptor-like factor 1
DHRS7 dehydrogenase/reductase (SDR family) member 7
DUS4L dihydrouridine synthase 4-like (S. cerevisiae)
EGFR epidermal growth factor receptor
EHD1 EH-domain containing 1
EML3 echinoderm microtubule associated protein like 3
ERAP1 endoplasmic reticulum aminopeptidase 1
FDPS farnesyl diphosphate synthase
FXYD2 FXYD domain containing ion transport regulator 2
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GADD45B growth arrest and DNA-damage-inducible, beta
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GJA9 gap junction protein, alpha 9, 59kDa
GLG1 golgi glycoprotein 1
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
GPALPP1 GPALPP motifs containing 1
GTPBP4 GTP binding protein 4
HAP1 huntingtin-associated protein 1
HDAC5 histone deacetylase 5
HRG histidine-rich glycoprotein
HSDL2 hydroxysteroid dehydrogenase like 2
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
INF2 inverted formin, FH2 and WH2 domain containing
INO80D INO80 complex subunit D
ISG20 interferon stimulated exonuclease gene 20kDa
KDM4C lysine (K)-specific demethylase 4C
KIAA0753 KIAA0753
KLHL20 kelch-like family member 20
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
KRT86 keratin 86, type II
LAMA4 laminin, alpha 4
LYPD3 LY6/PLAUR domain containing 3
MED25 mediator complex subunit 25
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
MRPS11 mitochondrial ribosomal protein S11
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
MTAP methylthioadenosine phosphorylase
MTM1 myotubularin 1
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
MTUS1 microtubule associated tumor suppressor 1
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle
NID2 nidogen 2 (osteonidogen)
NPY6R neuropeptide Y receptor Y6 (pseudogene)
NR4A2 nuclear receptor subfamily 4, group A, member 2
NUCB1 nucleobindin 1
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6
OSMR oncostatin M receptor
OSR2 odd-skipped related transciption factor 2
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
PCDH11Y protocadherin 11 Y-linked
PDGFB platelet-derived growth factor beta polypeptide
PHF20L1 PHD finger protein 20-like 1
PIP prolactin-induced protein
PKP3 plakophilin 3
PLXNA2 plexin A2
RAB11B RAB11B, member RAS oncogene family
RGS14 regulator of G-protein signaling 14
RHOT2 ras homolog family member T2
RNF122 ring finger protein 122
SCARB2 scavenger receptor class B, member 2
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae)
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SOS2 son of sevenless homolog 2 (Drosophila)
SPTLC1 serine palmitoyltransferase, long chain base subunit 1
SRSF7 serine/arginine-rich splicing factor 7
SYT11 synaptotagmin XI
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TBL2 transducin (beta)-like 2
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast)
TMCC1 transmembrane and coiled-coil domain family 1
TMEM63A transmembrane protein 63A
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TRIM25 tripartite motif containing 25
TSKU tsukushi, small leucine rich proteoglycan
TSSK2 testis-specific serine kinase 2
UBTF upstream binding transcription factor, RNA polymerase I
ULBP2 UL16 binding protein 2
ZBTB20 zinc finger and BTB domain containing 20
ZBTB43 zinc finger and BTB domain containing 43
ZNF408 zinc finger protein 408

decreased expression

Symbol Name
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3
ACIN1 apoptotic chromatin condensation inducer 1
ALG12 ALG12, alpha-1,6-mannosyltransferase
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
B3GAT3 beta-1,3-glucuronyltransferase 3
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BATF3 basic leucine zipper transcription factor, ATF-like 3
BRAF B-Raf proto-oncogene, serine/threonine kinase
C1ORF159 chromosome 1 open reading frame 159
C6ORF47 chromosome 6 open reading frame 47
CAMTA2 calmodulin binding transcription activator 2
CCDC68 coiled-coil domain containing 68
CCDC94 coiled-coil domain containing 94
CCS copper chaperone for superoxide dismutase
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CISH cytokine inducible SH2-containing protein
CLCN5 chloride channel, voltage-sensitive 5
CLDN8 claudin 8
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
COBL cordon-bleu WH2 repeat protein
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
DDN dendrin
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
DNMBP dynamin binding protein
ERF Ets2 repressor factor
ERN2 endoplasmic reticulum to nucleus signaling 2
FAF1 Fas (TNFRSF6) associated factor 1
FBRS fibrosin
FGF13 fibroblast growth factor 13
FPGS folylpolyglutamate synthase
GPN2 GPN-loop GTPase 2
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIST1H2AM histone cluster 1, H2am
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HYAL3 hyaluronoglucosaminidase 3
IL7 interleukin 7
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
MAST3 microtubule associated serine/threonine kinase 3
MCMBP minichromosome maintenance complex binding protein
MXRA8 matrix-remodelling associated 8
MYO1D myosin ID
MYOZ3 myozenin 3
NOTCH1 notch 1
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
P3H2 prolyl 3-hydroxylase 2
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
PAQR6 progestin and adipoQ receptor family member VI
PDE12 phosphodiesterase 12
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PECR peroxisomal trans-2-enoyl-CoA reductase
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLCD1 phospholipase C, delta 1
PLEKHA6 pleckstrin homology domain containing, family A member 6
POR P450 (cytochrome) oxidoreductase
PORCN porcupine homolog (Drosophila)
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRPH peripherin
PTCD2 pentatricopeptide repeat domain 2
PTGES2 prostaglandin E synthase 2
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RBM38 RNA binding motif protein 38
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RNF167 ring finger protein 167
RPL10L ribosomal protein L10-like
RUFY2 RUN and FYVE domain containing 2
SARS2 seryl-tRNA synthetase 2, mitochondrial
SCARA3 scavenger receptor class A, member 3
SCIN scinderin
SDC3 syndecan 3
SETD8 SET domain containing (lysine methyltransferase) 8
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SLC35G2 solute carrier family 35, member G2
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1
SPAG4 sperm associated antigen 4
SPATA1 spermatogenesis associated 1
STX17 syntaxin 17
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box)
TCTN1 tectonic family member 1
TESK1 testis-specific kinase 1
TMEM51 transmembrane protein 51
TMEM62 transmembrane protein 62
TMEM8B transmembrane protein 8B
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TPCN1 two pore segment channel 1
TTC31 tetratricopeptide repeat domain 31
USP27X ubiquitin specific peptidase 27, X-linked
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
ZMYM1 zinc finger, MYM-type 1
ZNF37BP zinc finger protein 37B, pseudogene
ZNF385D zinc finger protein 385D
ZSCAN31 zinc finger and SCAN domain containing 31