folic acid-containing compound metabolic process Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description The chemical reactions and pathways involving a folic acid-containing compound, i.e. any of a group of heterocyclic compounds based on the pteroic acid skeleton conjugated with one or more L-glutamic acid or L-glutamate units. (Gene Ontology, GO_0006760)
External Link http://amigo.geneontology.org/amigo/term/GO:0006760
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Genes

16 genes participating in the folic acid-containing compound metabolic process biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
DHFR dihydrofolate reductase
DHFR2 dihydrofolate reductase 2
FPGS folylpolyglutamate synthase
FTCD formimidoyltransferase cyclodeaminase
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial)
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLC25A32 solute carrier family 25 (mitochondrial folate carrier), member 32
SLC46A1 solute carrier family 46 (folate transporter), member 1
ST20-MTHFS ST20-MTHFS readthrough