FBJ murine osteosarcoma viral oncogene homolog B|The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 2354)
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14 genes co-occuring with the biological term fosb in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
