foxo3 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description forkhead box O3|This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 2309)
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Genes

37 genes co-occuring with the biological term foxo3 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
ATM ATM serine/threonine kinase
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
CD34 CD34 molecule
CDT1 chromatin licensing and DNA replication factor 1
CFH complement factor H
CXCL12 chemokine (C-X-C motif) ligand 12
E2F1 E2F transcription factor 1
EPO erythropoietin
FOXO1 forkhead box O1
FOXO3 forkhead box O3
FOXO4 forkhead box O4
IFNB1 interferon, beta 1, fibroblast
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
MIR10B microRNA 10b
MIR182 microRNA 182
MITF microphthalmia-associated transcription factor
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYC v-myc avian myelocytomatosis viral oncogene homolog
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
PRDM1 PR domain containing 1, with ZNF domain
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
SETD7 SET domain containing (lysine methyltransferase) 7
SIRT1 sirtuin 1
SIRT3 sirtuin 3
SMAD3 SMAD family member 3
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SP1 Sp1 transcription factor
STK11 serine/threonine kinase 11
STK4 serine/threonine kinase 4
TGFB1 transforming growth factor, beta 1
TP53 tumor protein p53
TRIM63 tripartite motif containing 63, E3 ubiquitin protein ligase
TSC22D3 TSC22 domain family, member 3
XPO1 exportin 1
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta