foxo4 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description forkhead box O4|This gene encodes a member of the O class of winged helix/forkhead transcription factor family. Proteins encoded by this class are regulated by factors involved in growth and differentiation indicating they play a role in these processes. A translocation involving this gene on chromosome X and the homolog of the Drosophila trithorax gene, encoding a DNA binding protein, located on chromosome 11 is associated with leukemia. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010] (NCBI Entrez Gene Database, 4303)
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Genes

25 genes co-occuring with the biological term foxo4 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
CREB1 cAMP responsive element binding protein 1
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
EPAS1 endothelial PAS domain protein 1
ERBB2 erb-b2 receptor tyrosine kinase 2
FOXO1 forkhead box O1
FOXO3 forkhead box O3
FOXO4 forkhead box O4
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
MAPK8 mitogen-activated protein kinase 8
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MIR421 microRNA 421
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae)
MTOR mechanistic target of rapamycin (serine/threonine kinase)
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PRKG1 protein kinase, cGMP-dependent, type I
RALA v-ral simian leukemia viral oncogene homolog A (ras related)
RPTOR regulatory associated protein of MTOR, complex 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SREBF2 sterol regulatory element binding transcription factor 2
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TNPO1 transportin 1
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta