foxp3 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description forkhead box P3|The protein encoded by this gene is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in this gene are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 50943)
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Genes

132 genes co-occuring with the biological term foxp3 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALK anaplastic lymphoma receptor tyrosine kinase
BIRC5 baculoviral IAP repeat containing 5
C3 complement component 3
CASP1 caspase 1, apoptosis-related cysteine peptidase
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CCL17 chemokine (C-C motif) ligand 17
CCL22 chemokine (C-C motif) ligand 22
CCR4 chemokine (C-C motif) receptor 4
CCR6 chemokine (C-C motif) receptor 6
CD2 CD2 molecule
CD200 CD200 molecule
CD274 CD274 molecule
CD28 CD28 molecule
CD4 CD4 molecule
CD52 CD52 molecule
CD58 CD58 molecule
CD8A CD8a molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CREB1 cAMP responsive element binding protein 1
CTAG1B cancer/testis antigen 1B
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR4 chemokine (C-X-C motif) receptor 4
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
EBI3 Epstein-Barr virus induced 3
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
ERBB2 erb-b2 receptor tyrosine kinase 2
FASLG Fas ligand (TNF superfamily, member 6)
FOXD1 forkhead box D1
FOXL2 forkhead box L2
FOXO1 forkhead box O1
FOXP3 forkhead box P3
FOXP4 forkhead box P4
GATA3 GATA binding protein 3
GDF15 growth differentiation factor 15
GJA1 gap junction protein, alpha 1, 43kDa
GPR83 G protein-coupled receptor 83
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HAVCR2 hepatitis A virus cellular receptor 2
HDAC1 histone deacetylase 1
HDAC9 histone deacetylase 9
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIST1H1B histone cluster 1, H1b
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-G major histocompatibility complex, class I, G
HMOX1 heme oxygenase 1
ICOS inducible T-cell co-stimulator
ICOSLG inducible T-cell co-stimulator ligand
IDO1 indoleamine 2,3-dioxygenase 1
IFNB1 interferon, beta 1, fibroblast
IFNG interferon, gamma
IKZF2 IKAROS family zinc finger 2 (Helios)
IL10 interleukin 10
IL17A interleukin 17A
IL1B interleukin 1, beta
IL22 interleukin 22
IL23A interleukin 23, alpha subunit p19
IL2RA interleukin 2 receptor, alpha
IL3RA interleukin 3 receptor, alpha (low affinity)
IL4 interleukin 4
IL6 interleukin 6
IL7R interleukin 7 receptor
IRF1 interferon regulatory factor 1
IRF7 interferon regulatory factor 7
ITCH itchy E3 ubiquitin protein ligase
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
KAT2B K(lysine) acetyltransferase 2B
KAT8 K(lysine) acetyltransferase 8
KDM5B lysine (K)-specific demethylase 5B
KDR kinase insert domain receptor
KLF10 Kruppel-like factor 10
KLRB1 killer cell lectin-like receptor subfamily B, member 1
KRT19 keratin 19, type I
LATS2 large tumor suppressor kinase 2
LCK LCK proto-oncogene, Src family tyrosine kinase
LGALS3 lectin, galactoside-binding, soluble, 3
LGMN legumain
LRRC32 leucine rich repeat containing 32
MIR21 microRNA 21
MIR210 microRNA 210
MIR31 microRNA 31
MKI67 marker of proliferation Ki-67
MMP9 matrix metallopeptidase 9
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NOD2 nucleotide-binding oligomerization domain containing 2
NOTCH1 notch 1
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
PDCD1 programmed cell death 1
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PRF1 perforin 1 (pore forming protein)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPRC protein tyrosine phosphatase, receptor type, C
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RORC RAR-related orphan receptor C
RUNX1 runt-related transcription factor 1
RUNX3 runt-related transcription factor 3
SATB1 SATB homeobox 1
SIRT1 sirtuin 1
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SMAD3 SMAD family member 3
SOCS1 suppressor of cytokine signaling 1
SOCS3 suppressor of cytokine signaling 3
SP3 Sp3 transcription factor
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
TGFB1 transforming growth factor, beta 1
TIA1 TIA1 cytotoxic granule-associated RNA binding protein
TJP1 tight junction protein 1
TLR4 toll-like receptor 4
TLR5 toll-like receptor 5
TLR9 toll-like receptor 9
TNF tumor necrosis factor
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TP53 tumor protein p53
TRIB1 tribbles pseudokinase 1
TSLP thymic stromal lymphopoietin
VAV1 vav 1 guanine nucleotide exchange factor
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
XBP1 X-box binding protein 1
YY1AP1 YY1 associated protein 1