| Dataset | GeneRIF Biological Term Annotations |
| Category | structural or functional annotations |
| Type | biological term |
| Description | FRAS1 related extracellular matrix protein 2|This gene encodes an integral membrane protein containing numerous CSPG (chondroitin sulfate proteoglycan element) repeats and Calx-beta domains. The encoded protein localizes to the basement membrane, forming a ternary complex that plays a role in epidermal-dermal interactions. This protein is important for the integrity of skin and renal epithelia. Mutations in this gene are associated with Fraser syndrome. [provided by RefSeq, Apr 2014] (NCBI Entrez Gene Database, 341640) |
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6 genes co-occuring with the biological term frem2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
