fulvestrant-1146 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the fulvestrant-1146 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD2 abhydrolase domain containing 2
AEN apoptosis enhancing nuclease
AREG amphiregulin
ARFRP1 ADP-ribosylation factor related protein 1
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BAX BCL2-associated X protein
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide
C1ORF105 chromosome 1 open reading frame 105
C7ORF43 chromosome 7 open reading frame 43
CCDC22 coiled-coil domain containing 22
CCL20 chemokine (C-C motif) ligand 20
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CRYL1 crystallin, lambda 1
CSNK1G2 casein kinase 1, gamma 2
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
CUL3 cullin 3
CYB561 cytochrome b561
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16
DTNA dystrobrevin, alpha
FAM127A family with sequence similarity 127, member A
FKBP8 FK506 binding protein 8, 38kDa
FLRT2 fibronectin leucine rich transmembrane protein 2
FRY furry homolog (Drosophila)
FSHB follicle stimulating hormone, beta polypeptide
G0S2 G0/G1 switch 2
GANAB glucosidase, alpha; neutral AB
GIF gastric intrinsic factor (vitamin B synthesis)
GLP1R glucagon-like peptide 1 receptor
GRSF1 G-rich RNA sequence binding factor 1
GTSE1 G-2 and S-phase expressed 1
HFE hemochromatosis
HIRA histone cell cycle regulator
HNRNPM heterogeneous nuclear ribonucleoprotein M
HOMER3 homer scaffolding protein 3
HOXA11 homeobox A11
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma
IDS iduronate 2-sulfatase
IFI30 interferon, gamma-inducible protein 30
IL24 interleukin 24
KIAA0753 KIAA0753
KLF6 Kruppel-like factor 6
KRT81 keratin 81, type II
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LINC00472 long intergenic non-protein coding RNA 472
MARK2 MAP/microtubule affinity-regulating kinase 2
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MFSD11 major facilitator superfamily domain containing 11
MLH3 mutL homolog 3
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MMP19 matrix metallopeptidase 19
MRPS12 mitochondrial ribosomal protein S12
MYO1B myosin IB
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NCOA2 nuclear receptor coactivator 2
NDRG2 NDRG family member 2
NINJ2 ninjurin 2
NMT1 N-myristoyltransferase 1
NOD2 nucleotide-binding oligomerization domain containing 2
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR4A3 nuclear receptor subfamily 4, group A, member 3
PARD3 par-3 family cell polarity regulator
PBX2 pre-B-cell leukemia homeobox 2
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLCD1 phospholipase C, delta 1
PLK3 polo-like kinase 3
PPAP2B phosphatidic acid phosphatase type 2B
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
RABEP2 rabaptin, RAB GTPase binding effector protein 2
RAP1GAP RAP1 GTPase activating protein
RCAN3 RCAN family member 3
RUNX1 runt-related transcription factor 1
RXRA retinoid X receptor, alpha
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SIGLEC9 sialic acid binding Ig-like lectin 9
SIPA1L1 signal-induced proliferation-associated 1 like 1
SLAMF7 SLAM family member 7
SSBP3 single stranded DNA binding protein 3
STAT5B signal transducer and activator of transcription 5B
STX7 syntaxin 7
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
TEX261 testis expressed 261
THBS1 thrombospondin 1
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast)
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TNS1 tensin 1
TOP3A topoisomerase (DNA) III alpha
TRAIP TRAF interacting protein
TTLL1 tubulin tyrosine ligase-like family member 1
TTLL5 tubulin tyrosine ligase-like family member 5
TULP3 tubby like protein 3
UPB1 ureidopropionase, beta
VAC14 Vac14 homolog (S. cerevisiae)
WDR62 WD repeat domain 62
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF250 zinc finger protein 250
ZNF552 zinc finger protein 552
ZNF696 zinc finger protein 696

decreased expression

Symbol Name
ADAM23 ADAM metallopeptidase domain 23
ADM adrenomedullin
APH1B APH1B gamma secretase subunit
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARL2 ADP-ribosylation factor-like 2
ARMC6 armadillo repeat containing 6
BAHD1 bromo adjacent homology domain containing 1
BAMBI BMP and activin membrane-bound inhibitor
C1QTNF3 C1q and tumor necrosis factor related protein 3
C5ORF30 chromosome 5 open reading frame 30
CAMTA2 calmodulin binding transcription activator 2
CCDC69 coiled-coil domain containing 69
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEP70 centrosomal protein 70kDa
CFAP44 cilia and flagella associated protein 44
CINP cyclin-dependent kinase 2 interacting protein
CLDN15 claudin 15
CORO7 coronin 7
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae)
CPPED1 calcineurin-like phosphoesterase domain containing 1
CRBN cereblon
CRIP1 cysteine-rich protein 1 (intestinal)
CSF1R colony stimulating factor 1 receptor
DENND2D DENN/MADD domain containing 2D
DTX4 deltex 4, E3 ubiquitin ligase
DYM dymeclin
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EML4 echinoderm microtubule associated protein like 4
ERCC4 excision repair cross-complementation group 4
ETAA1 Ewing tumor-associated antigen 1
ETV4 ets variant 4
FAM50B family with sequence similarity 50, member B
FANCC Fanconi anemia, complementation group C
FEM1C fem-1 homolog c (C. elegans)
FKBP5 FK506 binding protein 5
FPGS folylpolyglutamate synthase
GCH1 GTP cyclohydrolase 1
GPNMB glycoprotein (transmembrane) nmb
GPRC5C G protein-coupled receptor, class C, group 5, member C
HIST3H2A histone cluster 3, H2a
HRAS Harvey rat sarcoma viral oncogene homolog
IFI35 interferon-induced protein 35
KIF3B kinesin family member 3B
MAPKBP1 mitogen-activated protein kinase binding protein 1
MBIP MAP3K12 binding inhibitory protein 1
MBTPS2 membrane-bound transcription factor peptidase, site 2
MNAT1 MNAT CDK-activating kinase assembly factor 1
MORC3 MORC family CW-type zinc finger 3
MUM1 melanoma associated antigen (mutated) 1
NIPSNAP3B nipsnap homolog 3B (C. elegans)
NR1D2 nuclear receptor subfamily 1, group D, member 2
NT5DC3 5'-nucleotidase domain containing 3
NTHL1 nth endonuclease III-like 1 (E. coli)
PBLD phenazine biosynthesis-like protein domain containing
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PPDPF pancreatic progenitor cell differentiation and proliferation factor
PPP6R3 protein phosphatase 6, regulatory subunit 3
PTP4A3 protein tyrosine phosphatase type IVA, member 3
REEP4 receptor accessory protein 4
RHOBTB1 Rho-related BTB domain containing 1
RHOF ras homolog family member F (in filopodia)
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF122 ring finger protein 122
RNF167 ring finger protein 167
RNF219 ring finger protein 219
RNF31 ring finger protein 31
RPL13P5 ribosomal protein L13 pseudogene 5
SAMD9 sterile alpha motif domain containing 9
SEC31B SEC31 homolog B (S. cerevisiae)
SNX15 sorting nexin 15
SPATA2L spermatogenesis associated 2-like
STBD1 starch binding domain 1
TBXAS1 thromboxane A synthase 1 (platelet)
THBS4 thrombospondin 4
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TM6SF1 transmembrane 6 superfamily member 1
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM134 transmembrane protein 134
TMEM184B transmembrane protein 184B
TMEM209 transmembrane protein 209
TMEM254 transmembrane protein 254
TRDMT1 tRNA aspartic acid methyltransferase 1
TRIM21 tripartite motif containing 21
TWISTNB TWIST neighbor
UBQLN4 ubiquilin 4
URM1 ubiquitin related modifier 1
WDR60 WD repeat domain 60
XYLT2 xylosyltransferase II
ZMAT5 zinc finger, matrin-type 5
ZNF175 zinc finger protein 175
ZNF32 zinc finger protein 32
ZNF426 zinc finger protein 426
ZNF480 zinc finger protein 480
ZNF528 zinc finger protein 528
ZNF623 zinc finger protein 623
ZNF747 zinc finger protein 747