fulvestrant-1179 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the fulvestrant-1179 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGRE1 adhesion G protein-coupled receptor E1
ADGRL1 adhesion G protein-coupled receptor L1
AKAP9 A kinase (PRKA) anchor protein 9
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
ANKFY1 ankyrin repeat and FYVE domain containing 1
APAF1 apoptotic peptidase activating factor 1
APOL6 apolipoprotein L, 6
ARMC8 armadillo repeat containing 8
ARNT aryl hydrocarbon receptor nuclear translocator
ATG3 autophagy related 3
ATP2A3 ATPase, Ca++ transporting, ubiquitous
B3GALNT1 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
BCL7A B-cell CLL/lymphoma 7A
C16ORF59 chromosome 16 open reading frame 59
CASP2 caspase 2, apoptosis-related cysteine peptidase
CCT8 chaperonin containing TCP1, subunit 8 (theta)
CES3 carboxylesterase 3
COMT catechol-O-methyltransferase
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DEPTOR DEP domain containing MTOR-interacting protein
EGR1 early growth response 1
EMD emerin
EMILIN2 elastin microfibril interfacer 2
EPS8L1 EPS8-like 1
FAM105A family with sequence similarity 105, member A
FAM188A family with sequence similarity 188, member A
FCF1 FCF1 rRNA-processing protein
FHL1 four and a half LIM domains 1
FNTB farnesyltransferase, CAAX box, beta
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
FZD7 frizzled class receptor 7
GLIPR1 GLI pathogenesis-related 1
HDGFRP3 hepatoma-derived growth factor, related protein 3
HEMK1 HemK methyltransferase family member 1
HIST1H2BO histone cluster 1, H2bo
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
IFI30 interferon, gamma-inducible protein 30
IL27RA interleukin 27 receptor, alpha
IL6ST interleukin 6 signal transducer
ING1 inhibitor of growth family, member 1
IPP intracisternal A particle-promoted polypeptide
IRX5 iroquois homeobox 5
JRK Jrk homolog (mouse)
KLF6 Kruppel-like factor 6
LPAR4 lysophosphatidic acid receptor 4
MAP7 microtubule-associated protein 7
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2
MARK2 MAP/microtubule affinity-regulating kinase 2
MAST2 microtubule associated serine/threonine kinase 2
MAX MYC associated factor X
MDFIC MyoD family inhibitor domain containing
MMP25 matrix metallopeptidase 25
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
NF1 neurofibromin 1
NR4A1 nuclear receptor subfamily 4, group A, member 1
PCYT1A phosphate cytidylyltransferase 1, choline, alpha
PER3 period circadian clock 3
PHACTR2 phosphatase and actin regulator 2
PIGO phosphatidylinositol glycan anchor biosynthesis, class O
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLCD1 phospholipase C, delta 1
POLR2D polymerase (RNA) II (DNA directed) polypeptide D
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRUNE prune exopolyphosphatase
PTGER4 prostaglandin E receptor 4 (subtype EP4)
RGS5 regulator of G-protein signaling 5
RPL10 ribosomal protein L10
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SELPLG selectin P ligand
SH3PXD2A SH3 and PX domains 2A
SIRT5 sirtuin 5
SKI SKI proto-oncogene
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1
SLC35A2 solute carrier family 35 (UDP-galactose transporter), member A2
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOAT1 sterol O-acyltransferase 1
SOS2 son of sevenless homolog 2 (Drosophila)
STX7 syntaxin 7
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
SYNJ2 synaptojanin 2
TEP1 telomerase-associated protein 1
TEX261 testis expressed 261
TMOD1 tropomodulin 1
TOX4 TOX high mobility group box family member 4
TPMT thiopurine S-methyltransferase
TTC26 tetratricopeptide repeat domain 26
UBE2I ubiquitin-conjugating enzyme E2I
ZCCHC11 zinc finger, CCHC domain containing 11
ZMYND11 zinc finger, MYND-type containing 11
ZNF224 zinc finger protein 224
ZNF75D zinc finger protein 75D

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ADAM23 ADAM metallopeptidase domain 23
ADRB2 adrenoceptor beta 2, surface
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
ARSB arylsulfatase B
B3GNT1
C1QTNF3 C1q and tumor necrosis factor related protein 3
CALCOCO1 calcium binding and coiled-coil domain 1
CAPN1 calpain 1, (mu/I) large subunit
CCDC25 coiled-coil domain containing 25
CCRL2 chemokine (C-C motif) receptor-like 2
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CFAP44 cilia and flagella associated protein 44
CIDEB cell death-inducing DFFA-like effector b
CLSPN claspin
CSF1R colony stimulating factor 1 receptor
CTNNBIP1 catenin, beta interacting protein 1
CUL9 cullin 9
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DOLPP1 dolichyldiphosphatase 1
DTX4 deltex 4, E3 ubiquitin ligase
DVL1 dishevelled segment polarity protein 1
ENO2 enolase 2 (gamma, neuronal)
ERCC4 excision repair cross-complementation group 4
FAM127A family with sequence similarity 127, member A
FAM50A family with sequence similarity 50, member A
FOXN2 forkhead box N2
GAB2 GRB2-associated binding protein 2
GLTSCR1 glioma tumor suppressor candidate region gene 1
GNA12 guanine nucleotide binding protein (G protein) alpha 12
GRAMD1B GRAM domain containing 1B
HIST1H2BJ histone cluster 1, H2bj
HLA-J major histocompatibility complex, class I, J (pseudogene)
IPO8 importin 8
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
KIAA0355 KIAA0355
KPTN kaptin (actin binding protein)
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MICALL2 MICAL-like 2
MIR22HG MIR22 host gene
MITF microphthalmia-associated transcription factor
MOCS3 molybdenum cofactor synthesis 3
MPZ myelin protein zero
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NPIPB15 nuclear pore complex interacting protein family, member B15
NT5DC3 5'-nucleotidase domain containing 3
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PELI2 pellino E3 ubiquitin protein ligase family member 2
PGPEP1 pyroglutamyl-peptidase I
PIDD1 p53-induced death domain protein 1
PIEZO1 piezo-type mechanosensitive ion channel component 1
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PLTP phospholipid transfer protein
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRKCZ protein kinase C, zeta
PYCR1 pyrroline-5-carboxylate reductase 1
RAB33A RAB33A, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RECQL4 RecQ protein-like 4
RHBDF1 rhomboid 5 homolog 1 (Drosophila)
RNF122 ring finger protein 122
RPAP1 RNA polymerase II associated protein 1
SERTAD3 SERTA domain containing 3
SNORA21 small nucleolar RNA, H/ACA box 21
SPATA7 spermatogenesis associated 7
STIM1 stromal interaction molecule 1
STK25 serine/threonine kinase 25
SURF2 surfeit 2
TBX19 T-box 19
TGM5 transglutaminase 5
TM7SF2 transmembrane 7 superfamily member 2
TMEM110 transmembrane protein 110
TMEM209 transmembrane protein 209
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TSPAN13 tetraspanin 13
TUBA3C tubulin, alpha 3c
ULK1 unc-51 like autophagy activating kinase 1
VANGL1 VANGL planar cell polarity protein 1
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WBP2 WW domain binding protein 2
WNT10B wingless-type MMTV integration site family, member 10B
WWC2 WW and C2 domain containing 2
ZBED1 zinc finger, BED-type containing 1
ZBED8 zinc finger, BED-type containing 8
ZC2HC1A zinc finger, C2HC-type containing 1A
ZFYVE16 zinc finger, FYVE domain containing 16
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF212 zinc finger protein 212
ZNF215 zinc finger protein 215
ZNF408 zinc finger protein 408
ZNF574 zinc finger protein 574
ZNF623 zinc finger protein 623
ZNF74 zinc finger protein 74
ZNF767P zinc finger family member 767, pseudogene
ZNF816 zinc finger protein 816
ZNF85 zinc finger protein 85