| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the fulvestrant-1205 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAK1 | AP2 associated kinase 1 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ADGRE2 | adhesion G protein-coupled receptor E2 |
| AGFG2 | ArfGAP with FG repeats 2 |
| AHI1 | Abelson helper integration site 1 |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| ARRB2 | arrestin, beta 2 |
| ASIC1 | acid sensing (proton gated) ion channel 1 |
| ATG4B | autophagy related 4B, cysteine peptidase |
| BACH1 | BTB and CNC homology 1, basic leucine zipper transcription factor 1 |
| BAX | BCL2-associated X protein |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B |
| C22ORF46 | chromosome 22 open reading frame 46 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CACNG4 | calcium channel, voltage-dependent, gamma subunit 4 |
| CD58 | CD58 molecule |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) |
| CSTF2T | cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like |
| CTSZ | cathepsin Z |
| DGKA | diacylglycerol kinase, alpha 80kDa |
| DMBT1 | deleted in malignant brain tumors 1 |
| EFNB3 | ephrin-B3 |
| EGF | epidermal growth factor |
| EGR2 | early growth response 2 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) |
| ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 |
| ESR1 | estrogen receptor 1 |
| FAM134B | family with sequence similarity 134, member B |
| FGFR1 | fibroblast growth factor receptor 1 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FZD3 | frizzled class receptor 3 |
| GRK6 | G protein-coupled receptor kinase 6 |
| H2AFX | H2A histone family, member X |
| HIRA | histone cell cycle regulator |
| HPS1 | Hermansky-Pudlak syndrome 1 |
| HPS4 | Hermansky-Pudlak syndrome 4 |
| HTR1D | 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled |
| IFI44L | interferon-induced protein 44-like |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| INO80B | INO80 complex subunit B |
| INO80D | INO80 complex subunit D |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KIAA0754 | KIAA0754 |
| LOX | lysyl oxidase |
| LRRK1 | leucine-rich repeat kinase 1 |
| MAP3K7CL | MAP3K7 C-terminal like |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming |
| MVK | mevalonate kinase |
| NCAPH2 | non-SMC condensin II complex, subunit H2 |
| NF1 | neurofibromin 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PARVB | parvin, beta |
| PDGFA | platelet-derived growth factor alpha polypeptide |
| PDSS2 | prenyl (decaprenyl) diphosphate synthase, subunit 2 |
| PEX1 | peroxisomal biogenesis factor 1 |
| PHF3 | PHD finger protein 3 |
| PHLDB1 | pleckstrin homology-like domain, family B, member 1 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| POFUT1 | protein O-fucosyltransferase 1 |
| POM121 | POM121 transmembrane nucleoporin |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PRKAR1B | protein kinase, cAMP-dependent, regulatory, type I, beta |
| PRKCA | protein kinase C, alpha |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide |
| PTAFR | platelet-activating factor receptor |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| RHEB | Ras homolog enriched in brain |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RUNX1 | runt-related transcription factor 1 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B |
| SIVA1 | SIVA1, apoptosis-inducing factor |
| SLC24A1 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 |
| SLC46A3 | solute carrier family 46, member 3 |
| SLC4A3 | solute carrier family 4 (anion exchanger), member 3 |
| SNHG3 | small nucleolar RNA host gene 3 |
| SNX1 | sorting nexin 1 |
| SP1 | Sp1 transcription factor |
| SPHK2 | sphingosine kinase 2 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) |
| THBD | thrombomodulin |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TRIM25 | tripartite motif containing 25 |
| TRIM29 | tripartite motif containing 29 |
| TRIM3 | tripartite motif containing 3 |
| UNC119 | unc-119 homolog (C. elegans) |
| VAV2 | vav 2 guanine nucleotide exchange factor |
| ZFHX2 | zinc finger homeobox 2 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 |
| Symbol | Name |
|---|---|
| AGMAT | agmatine ureohydrolase (agmatinase) |
| AHDC1 | AT hook, DNA binding motif, containing 1 |
| ALPK1 | alpha-kinase 1 |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| APH1B | APH1B gamma secretase subunit |
| ARHGAP10 | Rho GTPase activating protein 10 |
| ARMC6 | armadillo repeat containing 6 |
| ASTE1 | asteroid homolog 1 (Drosophila) |
| BAK1 | BCL2-antagonist/killer 1 |
| BCL9 | B-cell CLL/lymphoma 9 |
| C1QTNF1 | C1q and tumor necrosis factor related protein 1 |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CCBL1 | cysteine conjugate-beta lyase, cytoplasmic |
| CCP110 | centriolar coiled coil protein 110kDa |
| CENPC | centromere protein C |
| CNN2 | calponin 2 |
| CNTNAP3B | contactin associated protein-like 3B |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| DCLRE1A | DNA cross-link repair 1A |
| DEAF1 | DEAF1 transcription factor |
| DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal |
| DHX35 | DEAH (Asp-Glu-Ala-His) box polypeptide 35 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DUSP8 | dual specificity phosphatase 8 |
| EDC4 | enhancer of mRNA decapping 4 |
| EHD3 | EH-domain containing 3 |
| EIF5A2 | eukaryotic translation initiation factor 5A2 |
| ESM1 | endothelial cell-specific molecule 1 |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| GPATCH2L | G patch domain containing 2-like |
| GPATCH3 | G patch domain containing 3 |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GRAMD3 | GRAM domain containing 3 |
| GRWD1 | glutamate-rich WD repeat containing 1 |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| HOXC10 | homeobox C10 |
| HPS6 | Hermansky-Pudlak syndrome 6 |
| HS1BP3 | HCLS1 binding protein 3 |
| HYMAI | hydatidiform mole associated and imprinted (non-protein coding) |
| IFI35 | interferon-induced protein 35 |
| IL17RA | interleukin 17 receptor A |
| IL32 | interleukin 32 |
| KLHL26 | kelch-like family member 26 |
| KRT37 | keratin 37, type I |
| KRT4 | keratin 4, type II |
| L2HGDH | L-2-hydroxyglutarate dehydrogenase |
| LMTK1 | lemur tail kinase 1 |
| LPAR3 | lysophosphatidic acid receptor 3 |
| MAGEA6 | melanoma antigen family A6 |
| MAGEF1 | melanoma antigen family F1 |
| MAP6D1 | MAP6 domain containing 1 |
| MCC | mutated in colorectal cancers |
| MMP13 | matrix metallopeptidase 13 |
| MMP9 | matrix metallopeptidase 9 |
| MRPL44 | mitochondrial ribosomal protein L44 |
| MUM1 | melanoma associated antigen (mutated) 1 |
| NDE1 | nudE neurodevelopment protein 1 |
| NDP | Norrie disease (pseudoglioma) |
| NINJ1 | ninjurin 1 |
| NOL12 | nucleolar protein 12 |
| NYNRIN | NYN domain and retroviral integrase containing |
| OCEL1 | occludin/ELL domain containing 1 |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PIGZ | phosphatidylinositol glycan anchor biosynthesis, class Z |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) |
| PLD2 | phospholipase D2 |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| POLM | polymerase (DNA directed), mu |
| POMT2 | protein-O-mannosyltransferase 2 |
| PPWD1 | peptidylprolyl isomerase domain and WD repeat containing 1 |
| PRKX | protein kinase, X-linked |
| PRPH | peripherin |
| PSKH1 | protein serine kinase H1 |
| PTPN9 | protein tyrosine phosphatase, non-receptor type 9 |
| PVRL2 | poliovirus receptor-related 2 (herpesvirus entry mediator B) |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| RGS17 | regulator of G-protein signaling 17 |
| RPAP2 | RNA polymerase II associated protein 2 |
| RUSC2 | RUN and SH3 domain containing 2 |
| SCAMP5 | secretory carrier membrane protein 5 |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
| SLC22A18 | solute carrier family 22, member 18 |
| SPEG | SPEG complex locus |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa |
| TRAIP | TRAF interacting protein |
| TRIM66 | tripartite motif containing 66 |
| UNKL | unkempt family zinc finger-like |
| USP6 | ubiquitin specific peptidase 6 |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| ZNF16 | zinc finger protein 16 |
| ZNF574 | zinc finger protein 574 |
| ZNF787 | zinc finger protein 787 |
