| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the fulvestrant-1238 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| ABCA11P | ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| ADCK2 | aarF domain containing kinase 2 |
| AGFG1 | ArfGAP with FG repeats 1 |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 |
| ALDOB | aldolase B, fructose-bisphosphate |
| ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha |
| ARSB | arylsulfatase B |
| ATAD5 | ATPase family, AAA domain containing 5 |
| BIN1 | bridging integrator 1 |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C17ORF80 | chromosome 17 open reading frame 80 |
| C19ORF60 | chromosome 19 open reading frame 60 |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 |
| CD6 | CD6 molecule |
| CTSZ | cathepsin Z |
| CYTH3 | cytohesin 3 |
| CYTH4 | cytohesin 4 |
| DHODH | dihydroorotate dehydrogenase (quinone) |
| DIXDC1 | DIX domain containing 1 |
| EFNB3 | ephrin-B3 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa |
| ETV6 | ets variant 6 |
| FASTKD2 | FAST kinase domains 2 |
| FBRS | fibrosin |
| FGF5 | fibroblast growth factor 5 |
| FGGY | FGGY carbohydrate kinase domain containing |
| FMOD | fibromodulin |
| FRS2 | fibroblast growth factor receptor substrate 2 |
| GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 |
| GAS7 | growth arrest-specific 7 |
| GGT1 | gamma-glutamyltransferase 1 |
| GLE1 | GLE1 RNA export mediator |
| GLI2 | GLI family zinc finger 2 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| GRK6 | G protein-coupled receptor kinase 6 |
| HOXD1 | homeobox D1 |
| IGHM | immunoglobulin heavy constant mu |
| IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta |
| ING1 | inhibitor of growth family, member 1 |
| ITGA2B | integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) |
| KCNG1 | potassium channel, voltage gated modifier subfamily G, member 1 |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 |
| KDELR3 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 |
| KLF12 | Kruppel-like factor 12 |
| KLHL36 | kelch-like family member 36 |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 |
| MFN2 | mitofusin 2 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) |
| MSL3 | male-specific lethal 3 homolog (Drosophila) |
| NMT1 | N-myristoyltransferase 1 |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| OAZ3 | ornithine decarboxylase antizyme 3 |
| OPLAH | 5-oxoprolinase (ATP-hydrolysing) |
| PARVB | parvin, beta |
| PATZ1 | POZ (BTB) and AT hook containing zinc finger 1 |
| PDE6C | phosphodiesterase 6C, cGMP-specific, cone, alpha prime |
| PDK2 | pyruvate dehydrogenase kinase, isozyme 2 |
| PHF3 | PHD finger protein 3 |
| PNMA2 | paraneoplastic Ma antigen 2 |
| PRKG2 | protein kinase, cGMP-dependent, type II |
| PSMD13 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 |
| PTPN18 | protein tyrosine phosphatase, non-receptor type 18 (brain-derived) |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RAD23B | RAD23 homolog B (S. cerevisiae) |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 |
| RASAL2 | RAS protein activator like 2 |
| RGS10 | regulator of G-protein signaling 10 |
| RGS4 | regulator of G-protein signaling 4 |
| RPL35A | ribosomal protein L35a |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SEC14L4 | SEC14-like 4 (S. cerevisiae) |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SLC16A7 | solute carrier family 16 (monocarboxylate transporter), member 7 |
| SMEK1 | SMEK homolog 1, suppressor of mek1 (Dictyostelium) |
| SOD3 | superoxide dismutase 3, extracellular |
| SPN | sialophorin |
| STK4 | serine/threonine kinase 4 |
| SUPT20H | suppressor of Ty 20 homolog (S. cerevisiae) |
| SYN2 | synapsin II |
| SYT11 | synaptotagmin XI |
| TBX19 | T-box 19 |
| THRB | thyroid hormone receptor, beta |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TRABD | TraB domain containing |
| TRIM25 | tripartite motif containing 25 |
| TSKU | tsukushi, small leucine rich proteoglycan |
| VAC14 | Vac14 homolog (S. cerevisiae) |
| VGLL3 | vestigial-like family member 3 |
| WIPF1 | WAS/WASL interacting protein family, member 1 |
| XDH | xanthine dehydrogenase |
| ZNF174 | zinc finger protein 174 |
| ZNF225 | zinc finger protein 225 |
| ZNF571 | zinc finger protein 571 |
| ZNF747 | zinc finger protein 747 |
| ZNF862 | zinc finger protein 862 |
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ABHD8 | abhydrolase domain containing 8 |
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| ACD | adrenocortical dysplasia homolog (mouse) |
| ALS2CL | ALS2 C-terminal like |
| APH1B | APH1B gamma secretase subunit |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 |
| ASB6 | ankyrin repeat and SOCS box containing 6 |
| C10ORF2 | chromosome 10 open reading frame 2 |
| C17ORF53 | chromosome 17 open reading frame 53 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| C1ORF115 | chromosome 1 open reading frame 115 |
| CA11 | carbonic anhydrase XI |
| CASZ1 | castor zinc finger 1 |
| CBY1 | chibby homolog 1 (Drosophila) |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CDR2L | cerebellar degeneration-related protein 2-like |
| CENPT | centromere protein T |
| CHPF | chondroitin polymerizing factor |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| CORO1A | coronin, actin binding protein, 1A |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| EFNA3 | ephrin-A3 |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM102A | family with sequence similarity 102, member A |
| FAM120C | family with sequence similarity 120C |
| FAM53B | family with sequence similarity 53, member B |
| FOXC1 | forkhead box C1 |
| GALT | galactose-1-phosphate uridylyltransferase |
| GBF1 | golgi brefeldin A resistant guanine nucleotide exchange factor 1 |
| GDPD3 | glycerophosphodiester phosphodiesterase domain containing 3 |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GPR19 | G protein-coupled receptor 19 |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GRPR | gastrin-releasing peptide receptor |
| HIST2H2AA3 | histone cluster 2, H2aa3 |
| HOXC4 | homeobox C4 |
| IFT54 | intraflagellar transport 54 |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KIAA0355 | KIAA0355 |
| KIAA1107 | KIAA1107 |
| LIN7B | lin-7 homolog B (C. elegans) |
| LRP5L | low density lipoprotein receptor-related protein 5-like |
| LRRC8E | leucine rich repeat containing 8 family, member E |
| MAFG | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MCC | mutated in colorectal cancers |
| ME3 | malic enzyme 3, NADP(+)-dependent, mitochondrial |
| MFSD10 | major facilitator superfamily domain containing 10 |
| MFSD6 | major facilitator superfamily domain containing 6 |
| MMP9 | matrix metallopeptidase 9 |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MRPL44 | mitochondrial ribosomal protein L44 |
| NME5 | NME/NM23 family member 5 |
| NOL12 | nucleolar protein 12 |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| NRAS | neuroblastoma RAS viral (v-ras) oncogene homolog |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| OCLN | occludin |
| OSR2 | odd-skipped related transciption factor 2 |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
| PLA2G15 | phospholipase A2, group XV |
| PLD2 | phospholipase D2 |
| PLEKHG6 | pleckstrin homology domain containing, family G (with RhoGef domain) member 6 |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| POLD4 | polymerase (DNA-directed), delta 4, accessory subunit |
| POMT2 | protein-O-mannosyltransferase 2 |
| PRR15L | proline rich 15-like |
| RGP1 | RGP1 retrograde golgi transport homolog (S. cerevisiae) |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RNF122 | ring finger protein 122 |
| RWDD2A | RWD domain containing 2A |
| SCD5 | stearoyl-CoA desaturase 5 |
| SH2B2 | SH2B adaptor protein 2 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| STRN | striatin, calmodulin binding protein |
| SUN2 | Sad1 and UNC84 domain containing 2 |
| TEX40 | testis expressed 40 |
| TGS1 | trimethylguanosine synthase 1 |
| THBS3 | thrombospondin 3 |
| TLN1 | talin 1 |
| TMEM184B | transmembrane protein 184B |
| TMEM2 | transmembrane protein 2 |
| TPCN1 | two pore segment channel 1 |
| TRMT12 | tRNA methyltransferase 12 homolog (S. cerevisiae) |
| UBQLN4 | ubiquilin 4 |
| USP20 | ubiquitin specific peptidase 20 |
| ZNF324 | zinc finger protein 324 |
| ZNF552 | zinc finger protein 552 |
| ZNF574 | zinc finger protein 574 |
| ZNF667 | zinc finger protein 667 |
