fulvestrant-1630 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

199 genes differentially expressed following the fulvestrant-1630 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ABCD4 ATP-binding cassette, sub-family D (ALD), member 4
ADCK2 aarF domain containing kinase 2
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
AP2S1 adaptor-related protein complex 2, sigma 1 subunit
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
BTG2 BTG family, member 2
BUD31 BUD31 homolog (S. cerevisiae)
C11ORF30 chromosome 11 open reading frame 30
CAMK1 calcium/calmodulin-dependent protein kinase I
CARD14 caspase recruitment domain family, member 14
CCDC68 coiled-coil domain containing 68
CDK12 cyclin-dependent kinase 12
CHD3 chromodomain helicase DNA binding protein 3
CLIP1 CAP-GLY domain containing linker protein 1
CLMN calmin (calponin-like, transmembrane)
CNPPD1 cyclin Pas1/PHO80 domain containing 1
CORO2A coronin, actin binding protein, 2A
CREM cAMP responsive element modulator
CUL7 cullin 7
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DCAF7 DDB1 and CUL4 associated factor 7
DDIT4 DNA-damage-inducible transcript 4
DMPK dystrophia myotonica-protein kinase
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DPY19L1P1 DPY19L1 pseudogene 1
EGFL7 EGF-like-domain, multiple 7
EXOC7 exocyst complex component 7
EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit
FBXL18 F-box and leucine-rich repeat protein 18
FBXO9 F-box protein 9
FGD1 FYVE, RhoGEF and PH domain containing 1
FRMD4A FERM domain containing 4A
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GPER1 G protein-coupled estrogen receptor 1
GRIK5 glutamate receptor, ionotropic, kainate 5
HCRP1 hepatocellular carcinoma-related HCRP1
HDAC5 histone deacetylase 5
HFE hemochromatosis
HMOX1 heme oxygenase 1
HOMER3 homer scaffolding protein 3
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IL4R interleukin 4 receptor
IQCG IQ motif containing G
KDM7A lysine (K)-specific demethylase 7A
KHNYN KH and NYN domain containing
KYNU kynureninase
LAMP1 lysosomal-associated membrane protein 1
LMO2 LIM domain only 2 (rhombotin-like 1)
LYN LYN proto-oncogene, Src family tyrosine kinase
LYPD1 LY6/PLAUR domain containing 1
MAP3K12 mitogen-activated protein kinase kinase kinase 12
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MTAP methylthioadenosine phosphorylase
MTMR3 myotubularin related protein 3
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
MYLIP myosin regulatory light chain interacting protein
MYO1B myosin IB
NDE1 nudE neurodevelopment protein 1
NLRX1 NLR family member X1
NUAK1 NUAK family, SNF1-like kinase, 1
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
PBX2 pre-B-cell leukemia homeobox 2
PDPK1 3-phosphoinositide dependent protein kinase 1
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta
PITX1 paired-like homeodomain 1
PLEKHA6 pleckstrin homology domain containing, family A member 6
POMT2 protein-O-mannosyltransferase 2
PRR4 proline rich 4 (lacrimal)
PTK6 protein tyrosine kinase 6
RECQL5 RecQ protein-like 5
RNF43 ring finger protein 43
RXRA retinoid X receptor, alpha
SAFB2 scaffold attachment factor B2
SASH1 SAM and SH3 domain containing 1
SFXN3 sideroflexin 3
SIRT5 sirtuin 5
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SMG6 SMG6 nonsense mediated mRNA decay factor
SOX4 SRY (sex determining region Y)-box 4
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STARD3 StAR-related lipid transfer (START) domain containing 3
STON1 stonin 1
SUN2 Sad1 and UNC84 domain containing 2
TBL1X transducin (beta)-like 1X-linked
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TMEM63A transmembrane protein 63A
TMEM80 transmembrane protein 80
TRIM21 tripartite motif containing 21
UNC93B1 unc-93 homolog B1 (C. elegans)
WBP2 WW domain binding protein 2
ZDHHC7 zinc finger, DHHC-type containing 7
ZER1 zyg-11 related, cell cycle regulator
ZFP36L1 ZFP36 ring finger protein-like 1
ZNF226 zinc finger protein 226
ZNF500 zinc finger protein 500
ZNF821 zinc finger protein 821

decreased expression

Symbol Name
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADAM15 ADAM metallopeptidase domain 15
AMD1 adenosylmethionine decarboxylase 1
ANKRD40 ankyrin repeat domain 40
ATAD3A ATPase family, AAA domain containing 3A
BAGE B melanoma antigen
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BRIP1 BRCA1 interacting protein C-terminal helicase 1
BYSL bystin-like
C17ORF70 chromosome 17 open reading frame 70
C1ORF56 chromosome 1 open reading frame 56
C21ORF91 chromosome 21 open reading frame 91
C4ORF19 chromosome 4 open reading frame 19
CA2 carbonic anhydrase II
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CBX4 chromobox homolog 4
CDKN2AIP CDKN2A interacting protein
CEP85 centrosomal protein 85kDa
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CISH cytokine inducible SH2-containing protein
CUEDC1 CUE domain containing 1
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CXCL12 chemokine (C-X-C motif) ligand 12
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DDA1 DET1 and DDB1 associated 1
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
E2F6 E2F transcription factor 6
EFNA3 ephrin-A3
EGR3 early growth response 3
EXOC5 exocyst complex component 5
FBXL6 F-box and leucine-rich repeat protein 6
FHL2 four and a half LIM domains 2
FOXC1 forkhead box C1
FSTL3 follistatin-like 3 (secreted glycoprotein)
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GALK1 galactokinase 1
GJA1 gap junction protein, alpha 1, 43kDa
GMEB1 glucocorticoid modulatory element binding protein 1
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GTF2I general transcription factor IIi
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8
HSPB8 heat shock 22kDa protein 8
IER3 immediate early response 3
INCENP inner centromere protein antigens 135/155kDa
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KIAA0125 KIAA0125
LOC257152 uncharacterized LOC257152
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MBTPS2 membrane-bound transcription factor peptidase, site 2
METTL1 methyltransferase like 1
METTL8 methyltransferase like 8
MPDU1 mannose-P-dolichol utilization defect 1
MPPED2 metallophosphoesterase domain containing 2
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MVD mevalonate (diphospho) decarboxylase
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
NIP7 NIP7, nucleolar pre-rRNA processing protein
NPY1R neuropeptide Y receptor Y1
NPY5R neuropeptide Y receptor Y5
PDZK1 PDZ domain containing 1
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E
PRSS23 protease, serine, 23
PTPRE protein tyrosine phosphatase, receptor type, E
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RHOBTB1 Rho-related BTB domain containing 1
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SAMHD1 SAM domain and HD domain 1
SCYL2 SCY1-like 2 (S. cerevisiae)
SETD8 SET domain containing (lysine methyltransferase) 8
SGK1 serum/glucocorticoid regulated kinase 1
SGPP1 sphingosine-1-phosphate phosphatase 1
SIAH2 siah E3 ubiquitin protein ligase 2
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma)
STC2 stanniocalcin 2
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TMEM104 transmembrane protein 104
TMEM164 transmembrane protein 164
TMEM230 transmembrane protein 230
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast)
TSKU tsukushi, small leucine rich proteoglycan
TXLNG taxilin gamma
UBQLN4 ubiquilin 4
WWC2 WW and C2 domain containing 2
XBP1 X-box binding protein 1
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
YIPF5 Yip1 domain family, member 5
ZNF205 zinc finger protein 205
ZNF211 zinc finger protein 211
ZNF562 zinc finger protein 562
ZSCAN31 zinc finger and SCAN domain containing 31