| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
199 genes differentially expressed following the fulvestrant-1663 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 |
| ANKRD26 | ankyrin repeat domain 26 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| ARHGAP35 | Rho GTPase activating protein 35 |
| ARNTL | aryl hydrocarbon receptor nuclear translocator-like |
| ARPC4 | actin related protein 2/3 complex, subunit 4, 20kDa |
| ASF1A | anti-silencing function 1A histone chaperone |
| ATOX1 | antioxidant 1 copper chaperone |
| BEX4 | brain expressed, X-linked 4 |
| BIK | BCL2-interacting killer (apoptosis-inducing) |
| BLVRA | biliverdin reductase A |
| BTG2 | BTG family, member 2 |
| BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CAMK2G | calcium/calmodulin-dependent protein kinase II gamma |
| CAPN9 | calpain 9 |
| CASKIN2 | CASK interacting protein 2 |
| CCDC87 | coiled-coil domain containing 87 |
| CCNG2 | cyclin G2 |
| CEP162 | centrosomal protein 162kDa |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CLMN | calmin (calponin-like, transmembrane) |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DENND1B | DENN/MADD domain containing 1B |
| EFNA1 | ephrin-A1 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) |
| ENTPD4 | ectonucleoside triphosphate diphosphohydrolase 4 |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| FADS2 | fatty acid desaturase 2 |
| FAM63A | family with sequence similarity 63, member A |
| GOLGA2 | golgin A2 |
| GPER1 | G protein-coupled estrogen receptor 1 |
| GPR37 | G protein-coupled receptor 37 (endothelin receptor type B-like) |
| HCRP1 | hepatocellular carcinoma-related HCRP1 |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H3E | histone cluster 1, H3e |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
| IL11 | interleukin 11 |
| IL1R1 | interleukin 1 receptor, type I |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| KIF13B | kinesin family member 13B |
| KLHL24 | kelch-like family member 24 |
| LDB1 | LIM domain binding 1 |
| LGALS8 | lectin, galactoside-binding, soluble, 8 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase |
| LYPD3 | LY6/PLAUR domain containing 3 |
| MARK4 | MAP/microtubule affinity-regulating kinase 4 |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MIR22HG | MIR22 host gene |
| MMP9 | matrix metallopeptidase 9 |
| MR1 | major histocompatibility complex, class I-related |
| MVK | mevalonate kinase |
| NF2 | neurofibromin 2 (merlin) |
| NFRKB | nuclear factor related to kappaB binding protein |
| NIPAL2 | NIPA-like domain containing 2 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PCDH9 | protocadherin 9 |
| PDGFA | platelet-derived growth factor alpha polypeptide |
| PDGFB | platelet-derived growth factor beta polypeptide |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) |
| PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase, type II, beta |
| PMP22 | peripheral myelin protein 22 |
| PPAP2B | phosphatidic acid phosphatase type 2B |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PPP2R3A | protein phosphatase 2, regulatory subunit B'', alpha |
| PRUNE | prune exopolyphosphatase |
| PTBP1 | polypyrimidine tract binding protein 1 |
| RAB27B | RAB27B, member RAS oncogene family |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RNF43 | ring finger protein 43 |
| SAFB2 | scaffold attachment factor B2 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 |
| SIDT1 | SID1 transmembrane family, member 1 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 |
| SMTN | smoothelin |
| SPRY2 | sprouty homolog 2 (Drosophila) |
| STBD1 | starch binding domain 1 |
| STOM | stomatin |
| STON1 | stonin 1 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b |
| TPST2 | tyrosylprotein sulfotransferase 2 |
| TREX1 | three prime repair exonuclease 1 |
| TRIM25 | tripartite motif containing 25 |
| TSC22D2 | TSC22 domain family, member 2 |
| TSPAN9 | tetraspanin 9 |
| TTC9 | tetratricopeptide repeat domain 9 |
| ZCCHC24 | zinc finger, CCHC domain containing 24 |
| ZNF500 | zinc finger protein 500 |
| ZNF592 | zinc finger protein 592 |
| Symbol | Name |
|---|---|
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
| ARMC6 | armadillo repeat containing 6 |
| BCL2L2 | BCL2-like 2 |
| BMP4 | bone morphogenetic protein 4 |
| C10ORF2 | chromosome 10 open reading frame 2 |
| C17ORF70 | chromosome 17 open reading frame 70 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| CBFA2T3 | core-binding factor, runt domain, alpha subunit 2; translocated to, 3 |
| CCND1 | cyclin D1 |
| CCP110 | centriolar coiled coil protein 110kDa |
| CD3EAP | CD3e molecule, epsilon associated protein |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CEP72 | centrosomal protein 72kDa |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHKB | choline kinase beta |
| CISH | cytokine inducible SH2-containing protein |
| CRYBG3 | beta-gamma crystallin domain containing 3 |
| CST6 | cystatin E/M |
| CTNNBIP1 | catenin, beta interacting protein 1 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DNAJC24 | DnaJ (Hsp40) homolog, subfamily C, member 24 |
| DNM1 | dynamin 1 |
| EFCAB2 | EF-hand calcium binding domain 2 |
| EGR3 | early growth response 3 |
| ENO2 | enolase 2 (gamma, neuronal) |
| ERCC5 | excision repair cross-complementation group 5 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM102A | family with sequence similarity 102, member A |
| FBXL15 | F-box and leucine-rich repeat protein 15 |
| FHL2 | four and a half LIM domains 2 |
| FJX1 | four jointed box 1 (Drosophila) |
| FOXC1 | forkhead box C1 |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| HIST1H2AJ | histone cluster 1, H2aj |
| HSPB8 | heat shock 22kDa protein 8 |
| IER3 | immediate early response 3 |
| IGFBP4 | insulin-like growth factor binding protein 4 |
| JMJD4 | jumonji domain containing 4 |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KDM5C | lysine (K)-specific demethylase 5C |
| KIAA0125 | KIAA0125 |
| LAMA3 | laminin, alpha 3 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) |
| LMNB1 | lamin B1 |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| MPPED2 | metallophosphoesterase domain containing 2 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NMRK1 | nicotinamide riboside kinase 1 |
| NPY1R | neuropeptide Y receptor Y1 |
| NPY5R | neuropeptide Y receptor Y5 |
| OPN3 | opsin 3 |
| PARG | poly (ADP-ribose) glycohydrolase |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PDZK1 | PDZ domain containing 1 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PRSS23 | protease, serine, 23 |
| PSTPIP2 | proline-serine-threonine phosphatase interacting protein 2 |
| RAB3A | RAB3A, member RAS oncogene family |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) |
| RBBP8 | retinoblastoma binding protein 8 |
| RBM41 | RNA binding motif protein 41 |
| RECQL4 | RecQ protein-like 4 |
| RHOBTB1 | Rho-related BTB domain containing 1 |
| RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SETD1A | SET domain containing 1A |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SIAH2 | siah E3 ubiquitin protein ligase 2 |
| SLC22A5 | solute carrier family 22 (organic cation/carnitine transporter), member 5 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 |
| SMAD7 | SMAD family member 7 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| STC2 | stanniocalcin 2 |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 |
| TBC1D17 | TBC1 domain family, member 17 |
| TBC1D4 | TBC1 domain family, member 4 |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
| TMPRSS3 | transmembrane protease, serine 3 |
| TPBG | trophoblast glycoprotein |
| TPCN1 | two pore segment channel 1 |
| TSKU | tsukushi, small leucine rich proteoglycan |
| TTC33 | tetratricopeptide repeat domain 33 |
| WDR3 | WD repeat domain 3 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| ZNF205 | zinc finger protein 205 |
| ZNF408 | zinc finger protein 408 |
| ZNF516 | zinc finger protein 516 |
| ZNF778 | zinc finger protein 778 |
